Recent developments from the Leishmania genome project

Current Opinion in Microbiology

Volumn 3, Issue 4, 2000, Pages 412-416

  Myler, Peter J ^a   Stuart, Kenneth D ^b  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTIG; PROTOZOAL DNA; TRANSFER RNA;

CHROMOSOME 1; CHROMOSOME 3; CHROMOSOME 4; CHROMOSOME STRUCTURE; COSMID; DNA REPLICATION ORIGIN; GENE CLUSTER; GENE MAPPING; GENE SEQUENCE; GENETIC ORGANIZATION; GENOME; LEISHMANIA; MICROBIAL GENETICS; NONHUMAN; REVIEW; RNA GENE;

EID: 0033902976     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(00)00113-2     Document Type: Review

References (31)

1. Ecology and epidemiology: New World
2. RNA editing in trypanosomatid mitochondria
3. mRNA processing in the Trypanosomatidae
4. Identification of a glycolipid precursor of the Trypanosoma brucei variant surface glycoprotein
5. Antigenic variation in African trypanosomes
6. Structure and function of telomeres
7. The Leishmania genome comprises 36 chromosomes conserved across widely divergent human pathogenic species
8. The complete chromosomal organization of the reference strain of the Leishmania genome project, L major 'Friedlin'
9. Conserved linkage groups associated with large-scale chromosomal rearrangements between Old World and New World Leishmania genomes
10. High conservation of the fine-scale organisation of chromosome 5 between two pathogenic Leishmania species
11. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd
12. Shuttle cosmid vectors for the trypanosomatid parasite Leishmania
13. Parasite genome analysis. A global map of the Leishmania major genome: Prelude to genomic sequencing
14. A physical map of the Leishmania major Friedlin genome
15. The Leishmania genome comes of age
16. Leishmania major Friedlin chromosome has an unusual distribution of protein-coding genes
17. Temporal order of RNA-processing reactions in trypanosomes: Rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts
18. A common pyrimidine-rich motif governs trans-splicing and poiyadenyiation of tubulin poiycistronic pre-mRNA in trypanosomes
19. Exonic sequences in the 5' untranslated region of alpha-tubulin mRNA modulate trans splicing in Trypanosoma brucei
20. A new twist in trypanosome RNA metabolism: Cis-splicing of pre-mRNA
21. The LD1 amplified element from Leishmania infantum encodes a homolog of ribosomal protein L37
22. An amplified DNA element in Leishmania encodes potential integral membrane and nucleotide binding proteins
23. A frequently amplified region in Leishmania contains a gene that is conserved in prokaryotes and eukaryotes
24. Conserved organization of genes in trypanosomatids
25. Physical and transcriptional analysis of the Trypanosoma brucei genome reveals a typical eukaryotic arrangement with close interspersion of RNA polymerase II- and Ill-transcribed genes
26. The size difference between Leishmania major Friedlin chromosome one homologues is localized to sub-telomeric repeats at one chromosomal end
27. The unusual gene organization of Leishmania major chromosome 1 may reflect novel transcription processes
28. Unravelling the Leishmania genome
29. Use of a cDNA microarray to analyse gene expression patterns in human cancer
30. Proteome research: Complementarity and limitations with respect to the RNA and DNA worlds
31. Reports from the cutting edge of parasitic genome analysis