β2-Integrin blockade driven by E-selectin promoter prevents neutrophil sequestration and lung injury in mice

Circulation Research

Volumn 87, Issue 3, 2000, Pages 254-260

  Xu, Ning ^a   Rahman, Arshad ^a   Minshall, Richard D ^a   Tiruppathi, Chinnaswamy ^a   Malik, Asrar B ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

CD11 antigen; CD18 antigen; E selectin; Endothelial cell; Neutrophil

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; LIPOPOLYSACCHARIDE; LIPOSOME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG INJURY; LUNG SEQUESTRATION; MALE; MOUSE; NEUTROPHIL; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION;

EID: 0033900406     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.87.3.254     Document Type: Article

References (36)

1. Neutrophil kinetics and lung injury
2. Effects of a neutrophil elastase inhibitor (ONO-5046) on acute pulmonary injury induced by tumor necrosis factor (TNFα) and activated neutrophils in isolated perfused rabbit lungs
3. Endotoxin-induced pulmonary vascular injury is mainly mediated by activated neutrophils in rat
4. Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia
5. Acute lung injury: The role of cytokines in the elicitation of neutrophil
6. Contribution of LFA-1 and Mac-1 m CD18-dependent neutrophil emigration in a neonatal rabbit model
7. Functional mapping of CD11b/CD18 epitopes important in neutrophil-epithelial interactions: A central role of the I domain
8. A hookworm glycoprotein that inhibits neutrophil function is a ligand of the integrin CD11b/CD18
9. 2 for a specific and high affinity ligand, NIF
10. Functional interaction between the integrin antagonist neutrophil inhibitory factor and I domain of CD11b/CD18
11. 2 integrins
12. 2 integrin-dependent mechanism
13. Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory protein and lectins
14. An NF-κB-like factor is essential but not sufficient for cytokine induction of endothelial leukocyte adhesion molecule-1 (ELAM-1) gene transcription
15. Three NF-κB binding sites in the human E-selectin gene required for maximal tumor necrosis factor α-induced expression
16. Overlapping pattern of activation of human endothelial cells by interleukin-1, tumor necrosis factor, and immune cells interferon
17. Labile protein plays a dual role in the control of endothelial leukocyte adhesion molecule-1 (ELAM-1) gene regulation
18. Identification of an endothelial leukocyte adhesion molecule
19. A T-cell enhancer cooperates with NF-κB to yield cytokine induction of E-selectin gene transcription in endothelial cells
20. Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene trhnscription
21. Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells
22. Cationic liposome-mediated gene transfer
23. Cationic liposome-mediated intravenous gene delivery
24. Hydrogen peroxide-induced increase in endothelial adhesiveness is dependent on ICAM-1 activation
25. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster model
26. Transvascular flux and tissue accrual of Evans blue: Effects of endotoxin and histamine
27. Effect of granulocytopenia on extravascular lung water content after microembolization
28. Cyclic AMP-independent ATF family members interact with NF-κB and function in the activation of the E-selectin promoter in response to cytokines
29. Cytokines and endothelial cell biology
30. Leukocyte adhesion to endothelium in inflammation
31. Neutrophil and neutrophil-endothelial cell adhesion in adult respiratopy distress syndrome
32. Regulation of neutrophil activation in acute lung injury
33. Endothelial activation in ARDS
34. Inhibition of neutrophil migration at the site of infection increases remote organ neutrophil sequestration and injury
35. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human intestinal microvascular endothelial cells
36. E-selectin expression in experimental models of inflammation in mice