Up-regulation of epidermal growth factor-receptors (EGF-R) by nicotine in cervical cancer cell lines: This effect may be mediated by EGF

American Journal of Reproductive Immunology

Volumn 44, Issue 2, 2000, Pages 114-120

  Mathu, Rajesh S ^a   Mathur, Subbi P ^a   Young, Roger C ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cell proliferation; Cervical cancer; Epidermal growth factor; Epidermal growth factor receptor

Indexed keywords

ANTIBODY; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; NICOTINE;

CANCER CELL CULTURE; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; PRIORITY JOURNAL; RECEPTOR UPREGULATION; UTERINE CERVIX CANCER; WART VIRUS;

CELL DIVISION; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; NICOTINE; RECEPTOR, EPIDERMAL GROWTH FACTOR; TUMOR CELLS, CULTURED; UP-REGULATION; UTERINE CERVICAL NEOPLASMS;

EID: 0033890327     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (24)

1. Chang JL, Tsao YP, Liu DW, Han CP, Lee WH, Chen SL: The expression of type-I growth factor receptors in the squamous neoplastic changes of the uterine cervix. Gynecol Oncol 1999; 73:62-71.
2. Kim JW, Kim YT, Kim DK, Song CH, Lee JW: Expression of epidermal growth factor receptor in carcinoma of the cervix. Gynecol Oncol 1996; 60:283-287.
3. Pfeiffer D, Stellwag B, Pfeiffer A, Borlinghaus P, Meier W, Scheidel P: Clinical implications of the epidermal growth factor receptor in the squamous cell carcinoma of the uterine cervix. Gynecol Oncol 1989; 33:146-150.
4. Biesterfeld S, Schuh S, Muys L, Rath W, Mittermayer C, Schroder W: Absence of epidermal growth factor receptor expression in squamous cell carcinoma of the uterine cervix is an indicator of limited tumor disease. Oncol Rep 1999; 6:205-209.
5. Kristensen GB, Holm R, Abeler VM, Trope CG: Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erb-2 in early cervical squamous cell carcinoma. An immunohistochemical study. Cancer 1996; 78:433-440.
6. Kersemaekers AM, Fleuren GJ, Kenter GG, Van der Broek LJ, Uljee SM, Hermans J, Van de Vijver MJ: Oncogene alterations in carcinomas of the uterine cervix: Overexpression of the epidermal growth factor receptor is associated with poor prognosis. Clin Cancer Res 1999; 5:577-586.
7. Kitagawa Y, Ueda M, Ando N, Ozawa S, Shimizu N, Kitajima M: Further evidence for prognostic significance of epidermal growth factor receptor gene amplification in patients with esophageal squamous cell carcinoma. Clin Cancer Res 1996; 2:909-914.
8. Hu G, Liu W, Mendelsohn J, Ellis LM, Radinsky R, Andreef M, Deisseroth AB: Expression of epidermal growth factor and human papillomavirus E6/E7 proteins in cervical carcinoma cells. J Can Res Inst 1997; 89:1271-1276.
9. Daling JL, Madeleine MM, Mcknight B, Carter JJ, Wipf GC, Ashley R, Schwartz SM, Beckman AM, Hagensee ME, Mandelson MT, Galloway DA: The relationship of human papillomavirus-related cervical tumors to cigarette smoking, oral contraceptive use, and prior herpes simplex virus type-2 infection. Cancer Epidemiol Biomark Prev 1996; 5:541-548.
10. Waggoner SE, Wang Xu: Nicotine increased proliferation of normal, malignant and HPV transformed human cervical cells. Gynecol Oncol 1994; 55:91-95.
11. Slattery ML, Robinson LM, Schuman KL, French TK, Abbott TM, Overall JC, Gardner JW: Cigarette smoking and exposure to passive smoke are risk factors for cervical cancer. JAMA 1989; 261:1593-1598.
12. Brinton LA, Schairer C, Henszel W, Stolley P, Lehman HF, Levine R, Savitz D: Cigarette smoking and invasive cervical cancer. JAMA 1986; 255:3265-3269.
13. Licciarolone JC, Brownson RC, Chang JC, Wilkins JR: Uterine cervical cancer risk in cigarette smokers: A meter-analytic study. Am J Prev Med 1990; 6:274-276.
14. Winkelstein W: Smoking and cancer of the uterine cervix: A hypothesis. Am J Epidemiol 1977; 106:257-259.
15. Rakowicz-Szulczynska EM, McIntosh DG, Perry M, Smith ML: PDGF-AA as mediator in nicotine dependent carcinogenesis. Carcinogenesis 1996; 17:1813-1818.
16. Sasson IM, Haley HJ, Hoffman D, Wynder EL, Hellberg D, Nilsson S: Cigarette smoking and neoplasia of the uterine cervix. N Engl J Med 1985; 312:315-316.
17. Hellberg D, Niisson S, Haley NJ, Hoffman D, Wynder E: Smoking and cervical intraepithelial neoplasia: nicotine and cotinine in serum and cervical mucus in smokers and non-smokers. Am J Obstet Gynecol 1988; 158:910-913.
18. Jones CJ, Schiffman MH, Kurman R, Jacob P, Benowitz NL: Elevated nicotine levels in cervical levages from passive smokers. Am J Public Health 1991; 81:378-379.
19. Cattaneo MG, D'atri F, Vicentini LM: Mechanism of mitogen-activated protein kinase activation by nicotine in small-cell lung carcinoma cells. Biochemical J 1997; 328:499-503.
20. Heusch WL, Maneckjee R: Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. Carcinogenesis 1998; 19:551-556.
21. Wennstrom S, Downward J: Role of phosphoinositide-3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor. Mol Cell Biol 1999; 19:4279-4288.
22. McClellan M, Kievit P, Auersperg N, Roadland K: Regulation of proliferation and apoptosis by epidermal growth factor and protein kinase C in human ovarian surface epithelial cells. Expt Cell Res 1999; 246:471-479.
23. Wang SL, Feng J, Correa A, Bringham M, Wu-Wang CY: Effects of in vivo treatments of nicotine and benzo(alpha)pyrene on the epidermal growth factor receptor in hamster buccal pouch. Toxicology 1996; 107:31-38.
24. Vogelstein B, Kinzler KW: The multistep nature of cancer. Trends Genet 1993; 9:138-141.