Complex formation between potyvirus VPg and translation eukaryotic initiation factor 4E correlates with virus infectivity

Journal of Virology

Volumn 74, Issue 17, 2000, Pages 7730-7737

  Leonard, S ^a   Plante, D ^a   Wittmann, S ^a   Daigneault, N ^a   Fortin, M G ^a   Laliberte, J F ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 4E;

AMINO ACID SUBSTITUTION; ARABIDOPSIS; ARTICLE; COMPLEX FORMATION; GENE MAPPING; MOSAIC VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RNA CAPPING; TRANSLATION INITIATION; VIROGENESIS; VIRUS INFECTIVITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARABIDOPSIS; ASPARTIC ACID; BINDING, COMPETITIVE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EUKARYOTIC INITIATION FACTOR-4E; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE INITIATION FACTORS; POTYVIRUS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA CAPS; SEQUENCE ANALYSIS, PROTEIN; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL CORE PROTEINS; VIRULENCE;

EID: 0033886549     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.17.7730-7737.2000     Document Type: Article

References (66)

1. Control of mRNA stability in higher plants
2. Altered cap recognition activity of initiation factor 4E in the yeast cell cycle division mutant cdc33
3. A novel inhibitor of cap-dependent translation initiation in yeast: p20 Competes with eIF4G for binding to eIF4E
4. Virus-induced host gene shutoff in animals and plants
5. Induction of HSP70 and polyubiquitin expression associated with plant virus replication
6. The plant translational apparatus
7. Identification of two messenger RNA cap binding proteins in wheat germ. Evidence that the 28-kDa subunit of eIF-4B and the 26-kDa subunit of eIF-4F are antigenically distinct polypeptides
8. Identification of an isozyme form of protein synthesis initiation factor 4F in plants
9. Cap-independent enhancement of translation by a plant potyvirus 5' nontranslated region
10. Bipartite signal sequence mediates nuclear translocation of the plant potyviral NIa protein
11. Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology
12. Expression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F
13. Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F
14. Modification of eukaryotic initiation factor 4F during infection by influenza virus
15. In vitro interactions between a potyvirus-encoded, genome-linked protein and RNA-dependent RNA polymerase
16. The role of eIF4 in cell proliferation
17. Translational control of cellular and viral mRNAs
18. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus
19. Interaction trap/two-hybrid system to identify interacting proteins
20. eIF4G dramatically enhances the binding of eIF4E to the mRNA 5'-cap structure
21. Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E
22. The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase
23. NIa and NIb of peanut stripe potyvirus are present in the nucleus of infected cells, but do not form inclusions
24. Site-directed mutagenesis by overlap extension using the polymerase chain reaction
25. A potyvirus polymerase interacts with the viral coat protein and VPg in yeast cells
26. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
27. Potyvirus genome-linked protein (VPg) determines pea seed-borne mosaic virus pathotype virulence in Pisum sativum
28. The proto-oncogene/translation factor eIF4E: A survey of its expression in breast carcinomas
29. Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme
30. Release of a 22-kDa protein derived from the amino-terminal domain of the 49-kDa NIa of turnip mosaic potyvirus in Escherichia coli
31. PHAS/4E-BPs as regulators of mRNA translation and cell proliferation
32. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap
33. Function of the tobacco etch virus RNA polymerase (NIb): Subcellular transport and protein-protein interaction with VPg/proteinase (NIa)
34. The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
35. A single amino acid change in viral genome-associated protein of potato virus Y correlates with resistance breaking in 'virgin A mutant' tobacco
36. Translation initiation factor 4E
37. Purification of turnip mosaic potyvirus viral protein genome-linked proteinase expressed in Escherichia coli and development of a quantitative assay for proteolytic activity
38. Mechanisms and regulation of eukaryotic protein synthesis
39. Replacement of the tyrosine residue that links a potyviral VPg to the viral RNA is lethal
40. A tyrosine residue in the small nuclear inclusion protein of tobacco vein mottling virus links the VPg to the viral RNA
41. Variations in the VPg protein allow a potyvirus to overcome va gene resistance in tobacco
42. Construction and analysis of infectious transcripts from a resistance-breaking strain of tobacco vein mottling potyvirus
43. Initiation of protein synthesis in eukaryotic cells
44. 4E-BP3, A new member of the eukaryotic initiation factor 4E-binding protein family
45. A reevaluation of the cap-binding protein, eIF4E, as a rate-limiting factor for the initiation of translation in reticulocyte lysate
46. Nuclear transport of plant potyviral proteins
47. Highlights and prospects of potyvirus molecular biology
48. The Arabidopsis thaliana cDNAs coding for eIF4E and eIF(iso)4E are not functionally equivalent for yeast complementation and differentially expressed during plant development
49. Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E
50. Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
51. Identification and characterization of a novel cap-binding protein from Arabidopsis thaliania
52. Infectivity of turnip mosaic potyvirus cDNA clones and transcripts on the systemic host Arabidopsis thaliana and local lesion hosts
53. Analysis of the VPg-proteinase (NIa) encoded by tobacco etch potyvirus: Effects of mutations on subcellular transport, proteolytic processing, and genome amplification
54. VPg of tobacco etch potyvirus is a host genotype-specific determinant for long-distance movement
55. 7GTP and mRNA analogues
56. The mRNA 5' cap-binding protein eIF4E and control of cell growth
57. Eukaryotic initiation factor 4GII (eIF4GII), but not eIF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection
58. Cap recap: The involvement of eIF-4F in regulating gene expression
59. Inhibition of host gene expression associated with plant virus replication
60. The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways
61. Wheat germ poly(A) binding protein enhances the binding affinity of eukaryotic initiation factor 4F and (iso)4F for cap analogues
62. Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressors, 4E-binding proteins
63. Interaction of the viral protein genome linked of turnip mosaic potyvirus with the translational eukaryotic initiation factor (iso)4E of Arabidopsis thaliana using the yeast two-hybrid system
64. A late adenovirus factor induces eIF-4E dephosphorylation and inhibition of cell protein synthesis