Hepatic microsomal desulfuration and dearylation of chlorpyrifos and parathion in fingerling channel catfish: Lack of effect from Aroclor 1254

Aquatic Toxicology

Volumn 50, Issue 1-2, 2000, Pages 141-151

  Straus, David L ^a   Schlenk, Daniel ^b   Chambers, Janice E ^a  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b Environ Toxicol Prog Res I   (United States)

Author keywords

Channel catfish; Chlorpyrifos; Dearylation; Desulfuration; P450s; Parathion

Indexed keywords

AROCLOR 1254; CHLORPYRIFOS; CYTOCHROME P450 1A; CYTOCHROME P450 2K1; CYTOCHROME P450 2M1; CYTOCHROME P450 3A27; CYTOCHROME P450 ISOENZYME; ETHOXYRESORUFIN DEETHYLASE; PARATHION; PHOSPHOROTHIOIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CATFISH; CONTROLLED STUDY; DESULFURIZATION; DETOXIFICATION; ENZYME INDUCTION; LIVER LEVEL; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; TOXICOKINETICS;

EID: 0033877122     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(99)00088-0     Document Type: Article

References (31)

1. Addison R.F., Zinck M.E., Willis D.E. Induction of hepatic mixed-function oxidase (MFO) enzymes in trout (Salvelinus fontinalis) by feeding Aroclor 1254 or 3-methylcholanthrene. Comp. Biochem. Physiol. C Pharmacol. Toxicol. 61C:1978;323-325.
2. Ankley G.T., Blazer V.S. Effect of diet on PCB-induced changes in xenobiotic metabolism in channel catfish (Ictalurus punctatus). Can. J. Fish. Aquat. Sci. 45:1988;132-137.
3. Ankley G.T., Blazer V.S., Reinert R.E., Agosin M. Effects of Aroclor 1254 on cytochrome P-450-dependent monooxygenase, glutathione S-transferase, and UDP-glucuronosyltransferase activities in channel catfish liver. Aquat. Toxicol. 9:1986;91-103.
4. Ankley G.T., Blazer V.S., Plakas S.M., Reinert R.E. Dietary lipid as a factor modulating xenobiotic metabolism in channel catfish (Ictalurus punctatus). Can. J. Fish. Aquat. Sci. 46:1989;1141-1146.
5. Benke G.M., Cheever K.L., Mirrer F.E., Murphy S.D. Comparative toxicity, anticholinesterase action and metabolism of methyl parathion and parathion in sunfish and mice. Toxicol. Appl. Pharmacol. 28:1974;97-109.
6. Binder R.L., Melancon M.J., Lech J.J. Factors influencing the persistence and metabolism of chemicals in fish. Drug Metab. Rev. 15(4):1984;697-724.
7. Boone J.S., Chambers J.E. Time course of inhibition of cholinesterase and aliesterase activities, and nonprotein sulfhydryl levels following exposure to organophosphorus insecticides in mosquitofish (Gambusia affinis). Fundam. Appl. Toxicol. 29:1996;202-207.
8. Boone J.S., Chambers J.E. Biochemical factors contributing to toxicity differences among chlorpyrifos, parathion, and methyl parathion in mosquitofish (Gambusia affinis). Aquat. Toxicol. 39:1997;333-343.
9. Chambers J.E., Yarbrough J.D. Xenobiotic biotransformation in fishes. Comp. Biochem. Physiol. C Pharmacol. Toxicol. 55C:1976;77-84.
10. Chambers J.E., Ma T., Boone J.S., Chambers H.W. Role of detoxication pathways in acute toxicity levels of phosphorothionate insecticides in the rat. Life Sci. 54(18):1994;1357-1364.
11. Elcombe C.R., Lech J.J. Induction and characterization of hemoprotein(s) P-450 and monooxygenation in rainbow trout (Salmo gairdneri). Toxicol. Appl. Pharmacol. 49:1979;437-450.
12. Forsyth C.S., Chambers J.E. Activation and degradation of the phosphorothionate insecticides parathion and EPN by rat brain. Biochem. Pharmacol. 38(10):1989;1597-1603.
13. Goksøyr A., Förlin L. The cytochrome P-450 system in fish, aquatic toxicology and environmental monitoring. Aquat. Toxicol. 22:1992;287-312.
14. Lake B.G., Paine A.J. Induction of hepatic cytochrome P-450 and drug metabolism by metyrapone in the rat: relevance to its effects in rat-liver cell culture. Xenobiotica. 13:1983;725-730.
15. Levi P.E., Hollingworth R.M., Hodgson E. Differences in oxidative dearylation and desulfuration of fenitrothion by cytochrome P-450 isozymes and in subsequent inhibition of monooxygenase activity. Pestic. Biochem. Physiol. 32:1988;224-231.
16. Lidman U., Förlin L., Molander O., Axelson G. Induction of the drug metabolizing system in rainbow trout (Salmo gairdneri) liver by polychlorinated biphenyls (PCBs). Acta Pharmacol. Toxicol. 39:1976;262-272.
17. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
18. Ma T., Chambers J.E. A kinetic analysis of hepatic microsomal activation of parathion and chlorpyrifos in control and phenobarbital-treated rats. J. Biochem. Toxicol. 10(2):1995;63-68.
19. Matsubara T., Koike M., Touchi A., Tochino Y., Sugeno K. Quantitative determination of cytochrome P-450 in rat liver homogenate. Anal. Biochem. 75:1976;596-603.
20. Mayer, F.L., Jr., Ellersieck, M.R., 1986. Manual of Acute Toxicity: Interpretation and Data Base for 410 Chemicals and 6 Species of Freshwater Animals. US Fish Wildlife Service, Resource Publication 160, 579 pp.
21. Melancon M.J., Lech J.J. Dose-effect relationship for induction of hepatic monooxygenase activity in rainbow trout and carp by Aroclor 1254. Aquat. Toxicol. 4:1983;51-61.
22. Murphy S.D. Liver metabolism and toxicity of thiophosphate insecticides in mammalian, avian, and piscine species. Proc. Soc. Exp. Biol. Med. 123:1966;392-398.
23. Neal R.A., Halpert J. Toxicology of thiono-sulfur compounds. Annu. Rev. Pharmacol. Toxicol. 22:1982;321-339.
24. Perkins E.J., Schlenk D. Immunochemical characterization of hepatic cytochrome P450 isozymes in the channel catfish: assessment of sexual, developmental and treatment-related effects. Comp. Biochem. Physiol. C Pharmacol. Toxicol. 121C:1998;305-310.
25. Potter J.L., O'Brien R.D. Parathion activation by livers of aquatic and terrestrial vertebrates. Science. 144:1964;55-57.
26. Ronis M.J.J., Celander M., Förlin L., Badger T.M. The use of polyclonal antibodies raised against rat and trout cytochrome P450 CYP1A1 orthologues to monitor environmental induction in the channel catfish (Ictalurus punctatus). Mar. Environ. Res. 34:1992;181-188.
27. Schlenk D., Ronis M.J.J., Miranda C.L., Buhler D.R. Channel catfish liver monooxygenases: immunological characterization of constitutive cytochromes P450 and the absence of active flavin-containing monooxygenases. Biochem. Pharmacol. 45(1):1993;217-221.
28. Stegeman J.J. The cytochromes P450 in fish. Hochachka P.W., Mommsen T.P. Biochemistry and Molecular Biology of Fishes, Vol. 2. 1993;137-158 Elsevier, New York.
29. Stegeman J.J., Hahn M.E. Biochemistry and molecular biology of monooxygenases: current perspectives on forms, functions and regulation of cytochrome P450 in aquatic species. Malins D.C., Ostrander G.K. Aquatic Toxicology: Molecular, Biochemical and Cellular Perspectives. 1994;87-206 Lewis Publishers, Boca Raton, FL.
30. Straus D.L., Chambers J.E. Inhibition of acetylcholinesterase and aliesterases of fingerling channel catfish by chlorpyrifos, parathion, and S,S,S-tributyl phosphorotrithioate (DEF). Aquat. Toxicol. 33:1995;311-324.
31. Wallace K.B., Dargan J.E. Intrinsic metabolic clearance of parathion and paraoxon by livers from fish and rodents. Toxicol. Appl. Pharmacol. 90:1987;235-242.