Melatonin inhibits testosterone secretion by acting at hypothalamo-pituitary-gonadal axis in the rat

Neuroendocrinology Letters

Volumn 21, Issue 4, 2000, Pages 301-306

  Yilmaz, B ^a   Kutlu, S ^a   Mogulkoc, R ^a   Canpolat, S ^a   Sandal, S ^a   Tarakci, B ^a   Kelestimur, H ^a  

^a FIRAT UNIVERSITY   (Turkey)

Author keywords

FSH; HCG; LH; Melatonin; Pinealectomy; Testosterone

Indexed keywords

CHORIONIC GONADOTROPIN; FOLLITROPIN; LUTEINIZING HORMONE; MELATONIN; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FEEDBACK SYSTEM; FOLLITROPIN BLOOD LEVEL; HISTOLOGY; HYPOPHYSIS ADRENAL SYSTEM; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NONHUMAN; PINEALECTOMY; RAT; TESTIS; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE RELEASE;

EID: 0033876087     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Mechanisms of control of reproductive physiology by the pineal gland and its hormones
2. Brief report: Melatonin-related hypogonadotropic hypogonadism
3. Immunohistochemical localization of gonadotropin and gonadal steroid receptors in human pineal glands
4. Increased nocturnal melatonin secretion in male patients with hypogonadotropic hypogonadism and delayed puberty
5. Circadian variations in plasma melatonin, FSH, LH, and prolactin and testosterone levels in infertile men
6. Short-term and long-term effects of melatonin on GnRH-stimulated gonadotropin secretion in pituitaries of sexually maturing rats
7. Melatonin inhibits luteinising hormone releasing hormone (LHRH) induction of LH release from fetal rat pituitary cells
8. Melatonin inhibited release of luteinising hormone (LH) via decrease of [Ca2+]i and cyclic AMP
9. Hypothalamic melatonin receptor sites revealed by autoradiography
10. Inhibitory effect of melatonin on GnRH-induced LH release
11. Direct regulation of mammalian reproductive organs by serotonin and melatonin
12. Melatonin receptors are present in adult rat Leydig cells and are coupled through a pertussis toxin-sensitive G-protein
13. Melatonin inhibits forskolin stimulated testosterone secretion by hamster Leydig cells in primary culture
14. Molecular and cellular analyses of melatonin receptor-mediated cAMP signalling in rat corpus epididymis
15. Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals
16. Nuclear localisation of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence
17. Melatonin receptors on human granulosa cell membranes
18. Effect of exogenous melatonin on neuroendocrine-reproductive function of middle-aged female rats
19. Melatonin enhances the luteinising hormone and follicle stimulating hormone responses to gonadotropin-releasing hormone in the follicular, but not in the luteal menstrual cycle phase
20. In vitro acute and prolonged effects of melatonin on purified rat Leydig cell steroidogenesis and adenosine 3',5'-monophosphate production
21. Melatonin inhibits naloxone-induced luteinizing hormone release in ovariectomised estrogen-primed rats
22. Hypothalamic control of gonadotrophin secretion by LHRH, FSHRH, NO, cytokines, and leptin
23. Effects of melatonin on the ultrastructure of Leydig cells in the pinealectomised rat
24. Daytime plasma melatonin levels in male hypogonadism