'Light' reading: Targeting tryptophans in cyclic nucleotide-gated channels

Journal of General Physiology

Volumn 116, Issue 2, 2000, Pages 223-225

  Gordon, S E ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC NUCLEOTIDE; POTASSIUM CHANNEL; POTASSIUM ION; TRYPTOPHAN;

ALLOSTERISM; AMINO ACID SEQUENCE; BINDING SITE; CHANNEL GATING; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; EXPERIMENTAL MODEL; LIGAND BINDING; MUTAGENESIS; NOTE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MODIFICATION; TECHNIQUE; ULTRAVIOLET RADIATION;

ANIMALS; CATTLE; ION CHANNEL GATING; ION CHANNELS; PHOTOCHEMISTRY; TRYPTOPHAN; ULTRAVIOLET RAYS;

EID: 0033872714     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.116.2.223     Document Type: Note

References (35)

1. Cyclic nucleotide-gated channels. Pore topology studied through the accessibility of reporter cysteines
2. Irreversible activation of cyclic nucleotide-gated ion channels by sulfhydryl-reactive derivatives of cyclic GMP
3. Movement of gating machinery during the activation of rod cyclic nucleotide-gated channels
4. Direct modulation by Ca(2+)-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons
5. + conduction and selectivity
6. 2- blockage, and ionic selectivity
7. Mechanism of tetracaine block of cyclic nucleotide-gated channels
8. Mechanisms of modulation by internal protons of cyclic nucleotide-gated channels cloned from sensory receptor cells
9. Altered ligand specificity by protonation in the ligand binding domain of cyclic nucleotide-gated channels
10. Direct interaction between amino- and carboxyl-terminal domains of cyclic nucleotide-gated channels
11. A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors
12. Localization of regions affecting an allosteric transition in cyclic nucleotide-activated channels
13. 2+ in cyclic nucleotide-gated channels
14. Molecular mechanism of cyclic-nucleotide-gated channel activation
15. Photochemical inactivation of enzymes
16. A quantitative description of membrane current and its application to conduction and excitation in nerve
17. Ultra-violet light-induced changes in membrane properties in secretory cells
18. Constraining ligand-binding site stoichiometry suggests that a cyclic nucleotide-gated channel is composed of two functional dimers
19. Cysteine-scanning mutagenesis of the cyclic nucleotide-gated channel ligand binding domain
20. Near-visible ultraviolet light induces a novel ubiquitous calcium-permeable cation current in mammalian cell lines
21. Effects of ultraviolet modification on the gating energetics of cyclic nucleotide-gated channels
22. Modification of cyclic nucleotide-gated ion channels by ultraviolet light
23. On the nature of allosteric transitions: A plausible model
24. C-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating
25. Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel
26. Stoichiometry and arrangement of subunits in rod cyclic nucleotide-gated channels
27. Regulatory subunit of protein kinase A: Structure of deletion mutant with cAMP binding domains
28. Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating
29. Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channels
30. Interdomain interactions underlying activation of cyclic nucleotide-gated channels
31. Photochemical reactions in amino acid residues and inactivation of enzymes during U.V.-irradiation. A review
32. + channel mediates apoptosis of myeloblastic leukemia cells
33. Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution
34. Three amino acids in the C-linker are major determinants of gating in cyclic nucleotide-gated channels