Decreased expression of p57(KIP2) mRNA in human bladder cancer

British Journal of Cancer

Volumn 83, Issue 5, 2000, Pages 626-631

  Oya, M ^a   Schulz, W A ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Chromosome 11p15.5; H19; IGF II; LOH analysis; Quantitative RT PCR

Indexed keywords

MESSENGER RNA;

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER CELL CULTURE; CANCER GENETICS; CHROMOSOME 11P; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033869670     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1298     Document Type: Article

References (42)

1. An HX, Niederacher D, Picard F, van Roeyen C, Bender HG and Beckmann MW (1996) Frequent allele loss on 9p21 -22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer. Genes, Chromosomes Cancer 17: 14-20
2. Clasen S, Schulz WA, Gerharz CD, Grimm MO, Christoph F and Schmitz-Dräger BJ (1998) Frequent and heterogeneous expression of cyclin-dependent kinase inhibitor WAFI/p21 protein and mRNA in urothelial carcinoma. Br J Cancer 77:515-521
3. Cooper MJ, Fischer M, Komitowski D, Shevelev A, Schulze E, Ariel I, Tykocinski ML, Miron S, Ilan J, de Groot N and Hochberg A (1996) Developmentally imprinted genes as markers for bladder tumor progression. J Urol 155: 120-127
4. Dao D, Walsh CP, Yuan L, Gorelov D, Feng L, Hensle T, Nisen P, Yamashiro DJ, Bestor TH and Tycko B (1999) Multipoint analysis of human chromosome 11pI5/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting. Hum Mol Genet 8: 1337-1352
5. Elkin M, Shevelev A, Schulze E, Tykocinsky M, Cooper M, Ariel I, Pode D, Kopf E, de Groot N and Hochberg A (1995) The expression of the imprinted H19 and IGF-2 genes in human bladder carcinoma. FEBS Lett 374: 57-61
6. Gibas Z and Gibas L (1997) Cytogenetics of bladder cancer. Cancer Genet. Cytogenet 95: 108-115
7. Grimm MO, Jürgens B, Schulz WA, Decken K, Makri D and Schmitz-Dräger BJ (1995) Inactivation of tumor suppressor genes and deregulation of the c-myc gene in urothelial cancer cell lines. Urol Rev 23: 293-300
8. Habuchi T, Ogawa O, Kaekehi Y, Ogura K, Koshiba M, Hamazaki S, Takahashi R, Sugiyama S and Yoshida O (1993) Accumulated allelic losses in the development of invasive urothelial cancer. Int J Cancer 53: 579-584
9. KIP2 and its reduced expression Wilms' tumors. Human Mol Genet 5: 783-788
10. Jürgens B, Schmitz-Dräger BJ and Schulz WA (1996) Hypomethylation of L1 LINE sequences prevailing in human urothelial carcinoma. Cancer Res 56: 5698-5703
11. Karnik P, Chen P, Paris M, Yeger H and Williams BRG (1998) Loss of heterozygosity at chromosome 11pI5 in Wilms tumors: identification of two independent regions. Oncogene 17: 237-240
12. KIP2 gene at 11pI5.5. Oncogene 12: 1365-1368
13. KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9: 639-649
14. KIP2 mutations in Beckwith-Wiedemann syndrome. Am J Hum Genet 61: 304-309
15. Lee MP, DeBaun M, Mitsuya K, Galonek HL, Brandenburg S, Oshimura M and Feinberg AP (1999) Loss of imprinting of a paternally expressed transcript, with antisense orientation to K QLTI, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting. Proc Natl Acad Sci USA 96: 5203-5208
16. Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A and Tilghman SM (1995) Disruption of imprinting caused by deletion of the H19 gene in mice. Nature 375: 34-39
17. KIP2, insulin-like growth faelor II, and H19, in adrenal tumors and cultured adrenal cells. J. Clin Endocrinol Metab 82: 1766-1771
18. CIPI CDK inhibitor family, is a candidate tumor suppressor gene. Genes Dev 9: 650-662
19. Matsuoka S, Thompson JS, Edwards MC, Barletta JM, Grundy P, Kalikin LM, Harper JW, Elledge SJ and Feinberg AP (1996) Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, on chromosome 11pI5. Proc Natl Acad Sci USA 93: 3026-3030
20. McCann AH, Miller N, O'Meara A, Pedersen I, Keogh K, Gorey T and Dervan PA (1996) Biallelic expression of the IGF2 gene in human breast disease. Hum Mol Genet 5: 1123-1127
21. Mori M, Inoue H, Shiraishi T, Mimori K, Shibuta K, Nakashima H, Mafune K, Tanaka Y, Ueo H, Barnard GF, Sugimachi K and Akiyoshi T (1996) Relaxation of insulin-like growth factor 2 gene imprinting in esophageal cancer. Int J Cancer 68:441-446
22. Moulton T, Crenshaw T, Hao Y, Moosikasuwan J, Lin N, Dembitzer F, Hensle T, Weiss L, McMorrow L, Loew T, Kraus W, Gerad W and Tycko B (1994) Epigenetic lesions at the H19 locus in Wilms' tumour patients. Nat Genet 7: 440-447
23. Nonomura N, Nishimura K, Miki T, Kanno N, Kojima Y, Yokoyama M and Okuyama A (1997) Loss of imprinting of the insulin-like growth factor II gene in renal cell carcinoma. Cancer Res 57: 2575-2577
24. Oda H, Kume H, Shimizu Y, Inoue T and Ishikawa T (1998) Loss of imprinting of IGF2 in renal cell carcinomas. Int J Cancer 75: 343-346
25. Ogawa O, Eccles MR, Szeto J, McNoe LA, Yun K, Maw MA, Smith PJ and Reeve AE (1993) Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature 362: 749-752
26. Okamoto K, Morrison IM, Taniguchi T and Reeve AE (1997) Epigenetic changes at the insulin-like growth factor II/H19 locus in developing kidney is an early event in Wilms tumorigenesis. Proc Natl Acad Sci USA 94: 5367-5371
27. KIP2 are present in some cases of Beckwith-Wiedmann syndrome but are rare or absent in Wilms tumors. Am J Hum Genet 61: 295-303
28. Oya M, Schmidt B, Schmitz-Dräger BJ and Schulz WA (1998) Expression of G1 →S transition regulatory molecules in human urothelial cancer. Jap J Cancer Res 89: 719-726
29. Rainier S, Johnson LA, Dobry CJ, Ping AJ, Grundy PE and Feinberg AP (1993) Relaxation of imprinted genes in human cancer. Nature 362: 747-755
30. KIP2 gene and its analysis in the G40I Wilms' tumor assay. Cancer Res 56: 1214-1218
31. Reik W, Brown KW, Schneid H, Le Boue Y, Bickmore W and Maher ER (1995) Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by an altered imprinting pattern in the IGF2-H19 domain. Hum Mol Genet 4: 2379-2385
32. Schulz WA, Krummeck A, Rösinger I, Eickelmann P, Neuhaus C, Ebert T, Schmitz-Dräger BJ and Sies H (1997) Increased frequency of a null-allele for NAD(P)H:quinone oxidoreductase in patients with urological malignancies. Pharmacoginetics 7: 235-239
33. Shaw ME and Knowles MA (1995) Deletion mapping of chromosome 11 in carcinoma of the bladder. Genes Chromosomes Cancer 13: 1-8
34. Smilinich NJ, Day CD, Filzpatrick GV, Caldwell GM, Lossie AC, Cooper PR, Smallwood AC, Joyce JA, Schofield PN, Reik W, Nicholls RD, Weksberg R, Driscoll DS, Maher ES, Shows TB and Higgins MJ (1999) A maternally methylated CpG island in KrLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedmann Syndrome. Proc Natl Acad Sci USA 96: 8664-8069
35. Steenman MJ, Rainier S, Dobry CJ, Grundy P, Horon IL and Feinberg AP (1994) Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumor. Nat Genet 7: 433-439
36. Tadokoro K, Fujii H, Inoue T and Yamada M (1991) Polymerase chain reaction (PCR) for detection of ApaI polymorphism at the insulin like growth factor II gene (IGF2). Nucleic Acids Res 19: 6967
37. Taniguchi T, Sullivan MJ, Ogawa O and Reeve AE (1995) Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms' tumor. Proc Natl Acad Sci USA 92: 2159-2163
38. KIP2 gene: alternative splicing, insertion/deletion polymorphisms in VNTR sequences in the coding region, and mutational analysis. Hum Gen 97: 625-631
39. Uyeno S, Aoki Y, Nata M, Sagisaka K, Kayama T, Yoshimoto T and Ono T (1996) IGF2 but not H19 shows loss of imprinting in human glioma. Cancer Res 56: 5356-5359
40. Voorter CEM, Ummelen MIJ, Ramaekers FSC and Hopman AHN (1996) Loss of chromosome 11 and 11 p/q imbalances in bladder cancer detected by fluorescence in situ hybridization. Int J Cancer 65: 301-307
41. Weksberg R, Shen DR, Fei YL, Song QL and Squire J (1993) Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome. Nat Genet 5: 143-150
42. KIP2 in the control of tissue growth and development. Genes & Dev 12: 3162-3167