Interaction of plakophilins with desmoplakin and intermediate filament proteins: An in vitro analysis

Journal of Cell Science

Volumn 113, Issue 13, 2000, Pages 2471-2483

  Hofmann, I ^a   Mertens, C ^a   Brettel, M ^a   Nimmrich, V ^a   Schnolzer, M ^a   Herrmann, H ^a  

^a Divisions of Immunology and Cell Biology   (Germany)

Author keywords

Cytokeratin; Desmoplakin; Desmosome; Intermediate filament; Junction; Plakophilin

Indexed keywords

CELL EXTRACT; CELL PROTEIN; CYTOKERATIN; DESMIN; DESMOPLAKIN; INTERMEDIATE FILAMENT PROTEIN; PLAKOPHILIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIMENTIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL STRAIN; CENTRIFUGATION; CONTROLLED STUDY; DESMOSOME; FRACTIONATION; HUMAN; IMMUNOPRECIPITATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; REGULATORY MECHANISM;

CELL EXTRACTS; CENTRIFUGATION; CYTOSKELETAL PROTEINS; DESMOPLAKINS; DESMOSOMES; INTERMEDIATE FILAMENT PROTEINS; MICROSCOPY, ELECTRON; PLAKOPHILINS; PROTEINS; RADIOLIGAND ASSAY; SURFACE PLASMON RESONANCE;

VERTEBRATA;

EID: 0033868312     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (85)

1. Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis
2. Intermediate filaments formed de novo from tail-less cytokeratins in the cytoplasm and in the nucleus
3. Plakophilin-3, a novel Armadillo-like protein present in nuclei and desmosomes of epithelial cells
4. Breaking the connection: Displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly
5. Normal keratinization in a spontaenously immortalized human keratinoyte cell line
6. The binding of plakoglobin to desmosomal cadherins: Patterns of binding sites and topogenic potential
7. Elucidating the early stages of keratin filament assembly
8. The complement of desmosomal plaque proteins in different cell types
9. Plakoglobin: A protein common to different kinds of intercellular adhering junctions
10. Assembly of stratum corneum basic protein and keratin filaments in macrofibrils
11. Transient expression of epidermal filaggrin culturd cells causes collapse of intermediate filament networks with alteration of cell shape and nuclear integrity
12. Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: A coordinated Sisyphus cycle
13. Organization of desmosomal plaque proteins in cells growing at low calcium concentrations
14. Identification of plakoglobin in oocytes and early embryos of Xenopus laevis: Maternal expression of a gene encoding a junctional plaque protein
15. Desmoplakins of epithelial and myocardial desmosomes are immunologically and biochemically related
16. Significance of two desmosome plaque-associated polypeptides of molecular weights 75,000 and 83,000
17. Immunolocalization of plakoglobin in endothelial junctions: Identification as a special type of zonulae adhaerentes
18. Plakoglobin is a component of the filamentous subplasmalemmal coat of lens cells
19. Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein
20. Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage
21. Structure of the human desmoplakins. Implications for function in the desmosomal plaque
22. The armadillo family of structural proteins
23. Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: Evidence for a subfamily of closely related proteins
24. Band 6 protein, a major constituent of desmosomes from stratified epithelia, is a novel member of the armadillo multigene family
25. Cell type-specific desmosomal plaque proteins of the plakoglobin family: Plakophilin 1 (band 6 protein)
26. The rod domain of NF-L determines neurofilament architecture, whereas the end domains specify filament assembly and network formation
27. Intermediate filament assembly: Temperature sensitivity and polymorphism
28. Intermediate filaments and integration of cytoplasm
29. Temperature-sensitive intermediate filament assembly: Alternative structures of Xenopus laevis vimentin in vitro and in vivo
30. Structure and assembly properties of the intermediate filament protein vimentin: The role of its head, rod and tail domains
31. Measuring the assembly kinetics and binding properties of intermediate filament proteins
32. Heterotypic interactions and filament assembly of type I and type II cytokeratins in vitro: Viscometry and determinations of relative affinities
33. Assembly and structure of calcium-induced thick vimentin filaments
34. Filaggrin expression in epidermolytic ichthyosis (epidermolytic hyperkeratosis)
35. Identification of a basic protein of M(r) 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia
36. Subplasmalemmal plaques of intercellular junctions: Common and distinguishing proteins
37. Plakophilin armadillo repeats, and nuclear localization
38. Making a connection: Direct binding between keratin intermediate filaments and desmosomal proteins
39. Desmosomes: Intercellular adhesive junctions specialized for attachment of intermediate filaments
40. The head domain of plakophilin-1 binds to desmoplakin and enhances its recruitment to desmosomes
41. Molecular characterization of the body site-specific human epidermal cytokeratin 9: CDNA cloning, amino acid sequence, and tissue specificity of gene expression
42. Inhibition of desmin expression blocks myoblast fusion and intereferes with the myogenic regulators MyoD and myogenin
43. The mechanism of interaction of filaggrin with intermediate filaments. The ionic zipper hypothesis
44. Interactions of the cytoplasmic domain of the desmosomal cadherin Dsg1 with plakoglobin
45. A homolog of the armadillo protein in Drosophila (plakoglobin) associated with e-cadherin
46. Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome
47. Skin fragility and hypohidrotic ectodermal dysplasia resulting from ablation of plakophilin 1
48. Two-hybrid analysis reveals fundamental differences in direct interactions between desmoplakin and cell type-specific intermediate filaments
49. Filensin: A new vimentin-binding, polymerization-competent, and membrane-associated protein of the lens fiber cell
50. Plakophilins 2a and 2b: Constitutive proteins of dual location in the karyoplasm and the desmosomal plaque
51. Desmosomal plakophilin 2 as a differentiation marker in normal and malignant tissues
52. The distribution of the desmosomal protein, plakophilin 1, in human skin and skin tumors
53. Biochemical and immunological characterization of desmoplakins I and II, the major polypeptides of the desmosomal plaque
54. Molecular map of the desmosomal plaque
55. Desmoplakin II. Purification and characterization
56. Intermediate Filament Structure, R.G. Landes Company, Austin
57. Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: Temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. I. Biochemical analysis
58. Regulation of desmosome assembly in MDCK epithelial cells: Coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane
59. The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin
60. A repeating amino acid motif shared by proteins with diverse cellular roles
61. Truncation mutagenesis of the non-α-helical carboxyterminal tail domain of vimentin reveals contributions to cellular loalization but not to filament assembly
62. The plakin family: Versatile organizers of cytoskeletal architecture
63. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
64. Cytoskeletal architecture and epithelial differentiation: Molecular determinants of cell interaction and cytoskeletal filament anchorage
65. A novel type of adhering junction in an epithelioid tumorigenic rat cell culture line
66. Desmosomes and cytoskeletal architecture in epithelial differentiation: Cell type-specific plaque components and intermediate filament anchorage
67. Plakophilins 1a and 1b: Widespread nuclear proteins recruited in specific epithelial cells as desmosomal plaque components
68. Plakophilin 3 - a novel cell-type-specific desmosomal plaque protein
69. Desmosomes and hemidesmosomes: Constitutive molecular components
70. Defining the interactions between intermediate filaments and desmosomes
71. The desmoplakin carboxyl terminus coaligns with and specifically disrupts intermediate filament networks when expressed in cultured cells
72. Functional analysis of desmoplakin domains: Specification of the interaction with keratin vesus vimentin intermediate filament networks
73. Phosphorylation of the desmoplakin COOH terminus negatively regulates its interaction with keratin intermediate filament networks
74. Characterization of a class of cationic proteins that specifically interact with intermediate filaments
75. cDNA-cloning of the developmentally regulated lamin LIII of Xenopus laevis
76. Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage
77. Identification of the plakoglobin-binding domain in desmoglein and its role in plaque assembly and intermediate filament anchorage
78. Identification of amino acid sequence motifs in desmocollin, a desmosomal glycoprotein, that are required for plakoglobin binding and plaque formation
79. Desmocalmin: A calmodulin-binding high molecular weight protein isolated form desmosomes
80. Molecular structure of the human desmoplakin I and II amino terminus
81. Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins: Identification of unique and shared domains
82. Is filaggrin really a filament-aggregating protein in vivo?
83. Desmosomal cadherin binding domains of plakoglobin