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Volumn 6, Issue 8, 2000, Pages 1166-1173

Alterations in the peptidyltransferase and decoding domains of ribosomal RNA suppress mutations in the elongation factor G gene

Author keywords

EF G mutants; Ribosomes; rRNA mutants; Translocation

Indexed keywords

ELONGATION FACTOR G; PEPTIDYLTRANSFERASE; RIBOSOME RNA;

EID: 0033866474     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200000534     Document Type: Article
Times cited : (4)

References (50)
  • 2
    • 0032568584 scopus 로고    scopus 로고
    • Visualization of elongation factor G on the Escherichia coli 70S ribosome: The mechanism of translocation
    • Agrawal R, Penczek P, Grassucci R, Frank J. 1998. Visualization of Elongation Factor G on the Escherichia coli 70S ribosome: The mechanism of translocation. Proc Natl Acad Sci USA 95:6134-6138.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6134-6138
    • Agrawal, R.1    Penczek, P.2    Grassucci, R.3    Frank, J.4
  • 3
    • 0033607003 scopus 로고    scopus 로고
    • Placement of protein and RNA structures into a 5 å-resolution map of the 50S ribosomal subunit
    • Ban N, Nissen P, Hansen J, Capel M, Moore P, Steitz T. 1999. Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit. Nature 400:841-847.
    • (1999) Nature , vol.400 , pp. 841-847
    • Ban, N.1    Nissen, P.2    Hansen, J.3    Capel, M.4    Moore, P.5    Steitz, T.6
  • 5
    • 0029654105 scopus 로고
    • GTPases: A family of molecular switches and clocks
    • Bourne H. 1995. GTPases: A family of molecular switches and clocks. Philos Trans R Soc Lond B Biol Sci 349:283-289.
    • (1995) Philos Trans R Soc Lond B Biol Sci , vol.349 , pp. 283-289
    • Bourne, H.1
  • 6
    • 0025010979 scopus 로고
    • The GTPase superfamily: A conserved switch for diverse cell functions
    • Bourne H, Sanders D, McCormick F. 1990. The GTPase superfamily: A conserved switch for diverse cell functions. Nature 348:125-131.
    • (1990) Nature , vol.348 , pp. 125-131
    • Bourne, H.1    Sanders, D.2    McCormick, F.3
  • 7
    • 0019358924 scopus 로고
    • Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli
    • Brosius J, Ullrich A, Raker M, Gray A, Dull T, Guttel R, Noller H. 1981. Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli. Plasmid 6:112-118.
    • (1981) Plasmid , vol.6 , pp. 112-118
    • Brosius, J.1    Ullrich, A.2    Raker, M.3    Gray, A.4    Dull, T.5    Guttel, R.6    Noller, H.7
  • 8
    • 0032881809 scopus 로고    scopus 로고
    • X-ray crystal structures of 70S ribosome functional complexes
    • Gate J, Yusupov M, Yusupova G, Earnest T, Noller H. 1999. X-ray crystal structures of 70S ribosome functional complexes. Science 235:2095-2104.
    • (1999) Science , vol.235 , pp. 2095-2104
    • Gate, J.1    Yusupov, M.2    Yusupova, G.3    Earnest, T.4    Noller, H.5
  • 10
    • 0030850032 scopus 로고    scopus 로고
    • The conformational properties of elongation factor G and the mechanism of translocation
    • Czworkowski J, Moore P. 1997. The conformational properties of elongation factor G and the mechanism of translocation, Biochemistry 36:10327-10334.
    • (1997) Biochemistry , vol.36 , pp. 10327-10334
    • Czworkowski, J.1    Moore, P.2
  • 11
    • 0027980558 scopus 로고
    • The crystal structure of elongation factor G complexed with GDP, at 2.7 angstroms resolution
    • Czworkowski J, Wang J, Steitz T, Moore P. 1994. The crystal structure of elongation factor G complexed with GDP, at 2.7 angstroms resolution. EMBO J 13:3661-3668.
    • (1994) EMBO J , vol.13 , pp. 3661-3668
    • Czworkowski, J.1    Wang, J.2    Steitz, T.3    Moore, P.4
  • 12
    • 0024375425 scopus 로고
    • The functional role of ribosomal RNA in protein synthesis
    • Dahlberg A. 1989. The functional role of ribosomal RNA in protein synthesis. Cell 57:525-529.
    • (1989) Cell , vol.57 , pp. 525-529
    • Dahlberg, A.1
  • 13
    • 0025305692 scopus 로고
    • Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16S ribosomal RNA
    • De Stasio E, Dahlberg A. 1990. Effects of mutagenesis of a conserved base-paired site near the decoding region of Escherichia coli 16S ribosomal RNA. J Mol Biol 272:127-133.
    • (1990) J Mol Biol , vol.272 , pp. 127-133
    • De Stasio, E.1    Dahlberg, A.2
  • 14
    • 0024424033 scopus 로고
    • Mutations in 16S ribosomal RNA disrupt antibiotic-RNA interactions
    • De Stasio E, Moazed D, Noller H, Dahlberg A. 1989. Mutations in 16S ribosomal RNA disrupt antibiotic-RNA interactions. EMBO J 8:1213-1216.
    • (1989) EMBO J , vol.8 , pp. 1213-1216
    • De Stasio, E.1    Moazed, D.2    Noller, H.3    Dahlberg, A.4
  • 15
    • 0026681280 scopus 로고
    • Three widely separated positions in the 16S RNA lie in or close to the ribosomal decoding region: A site-directed cross-linking study with mRNA analogues
    • Dontsova O, Dokudovskaya S, Kopylov A, Bogdanov A, Rinke-Appel J, Junke N, Brimacombe R. 1992. Three widely separated positions in the 16S RNA lie in or close to the ribosomal decoding region: A site-directed cross-linking study with mRNA analogues. EMBO J 11:3105-3116.
    • (1992) EMBO J , vol.11 , pp. 3105-3116
    • Dontsova, O.1    Dokudovskaya, S.2    Kopylov, A.3    Bogdanov, A.4    Rinke-Appel, J.5    Junke, N.6    Brimacombe, R.7
  • 16
    • 0026601409 scopus 로고
    • Functional interactions within 23S rRNA involving the peptidyltransferase center
    • Douthwaite S. 1992. Functional interactions within 23S rRNA involving the peptidyltransferase center. J Bacteriol 174:1333-1338.
    • (1992) J Bacteriol , vol.174 , pp. 1333-1338
    • Douthwaite, S.1
  • 17
    • 0001420054 scopus 로고
    • Stimulation of "non-enzymic" translocation in ribosomes by p-chloromercuribenzoate
    • Gavrilova L, Spirin A. 1971. Stimulation of "non-enzymic" translocation in ribosomes by p-chloromercuribenzoate. FEBS Lett 17: 324-326.
    • (1971) FEBS Lett , vol.17 , pp. 324-326
    • Gavrilova, L.1    Spirin, A.2
  • 18
    • 0014211237 scopus 로고
    • Lysis of Escherichia coli with a neutral detergent
    • Godson G, Sinsheimer R. 1967. Lysis of Escherichia coli with a neutral detergent. Biochim Biophys Acta 749:476-488.
    • (1967) Biochim Biophys Acta , vol.749 , pp. 476-488
    • Godson, G.1    Sinsheimer, R.2
  • 19
    • 0019946582 scopus 로고
    • Site-directed mutagenesis of ribosomal RNA. Construction and characterization of deletion mutants
    • Gourse R, Stark M, Dahlberg A. 1982. Site-directed mutagenesis of ribosomal RNA. Construction and characterization of deletion mutants. J Mol Biol 759:397-416.
    • (1982) J Mol Biol , vol.759 , pp. 397-416
    • Gourse, R.1    Stark, M.2    Dahlberg, A.3
  • 20
    • 0020959710 scopus 로고
    • Studies on transformation of Escherichia coli with plasmids
    • Hanahan D. 1983. Studies on transformation of Escherichia coli with plasmids. J Mol Biol 766:557-580.
    • (1983) J Mol Biol , vol.766 , pp. 557-580
    • Hanahan, D.1
  • 21
    • 0028037409 scopus 로고
    • Carboxy-terminal amino acid residues in elongation factor G essential for ribosome association and translocation
    • Hou Y, Yaskowiak E, March P. 1994a. Carboxy-terminal amino acid residues in elongation factor G essential for ribosome association and translocation. J Bacteriol 176:7038-7044.
    • (1994) J Bacteriol , vol.176 , pp. 7038-7044
    • Hou, Y.1    Yaskowiak, E.2    March, P.3
  • 22
    • 0028040002 scopus 로고
    • In vivo selection of conditional-lethal mutations in the gene encoding elongation factor G of Escherichia coli
    • Hou Y, Yi-Ping Lin J, Sharer D, March P. 1994b. In vivo selection of conditional-lethal mutations in the gene encoding elongation factor G of Escherichia coli. J Bacteriol 176:123-129.
    • (1994) J Bacteriol , vol.176 , pp. 123-129
    • Hou, Y.1    Yi-Ping Lin, J.2    Sharer, D.3    March, P.4
  • 23
    • 0017135816 scopus 로고
    • Mutagenesis of plasmid DNA with hydroxylamine: Isolation of mutants of multicopy plasmids
    • Humphreys G, Willshaw G, Smith H, Anderson E. 1976. Mutagenesis of plasmid DNA with hydroxylamine: Isolation of mutants of multicopy plasmids. Mol Gen Genet 145:101-108.
    • (1976) Mol Gen Genet , vol.145 , pp. 101-108
    • Humphreys, G.1    Willshaw, G.2    Smith, H.3    Anderson, E.4
  • 24
    • 0016220086 scopus 로고
    • The role of guanosine triphosphate in translocation reaction catalyzed by elongation factor G
    • Inoue-Yokosawa N, Ishikawa C, Kaziro Y. 1974. The role of guanosine triphosphate in translocation reaction catalyzed by elongation factor G. J Biol Chem 249:4321-4323.
    • (1974) J Biol Chem , vol.249 , pp. 4321-4323
    • Inoue-Yokosawa, N.1    Ishikawa, C.2    Kaziro, Y.3
  • 25
    • 0028214276 scopus 로고
    • Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium
    • Johanson U, Hughes D. 1994. Fusidic acid-resistant mutants define three regions in elongation factor G of Salmonella typhimurium. Gene 143:55-59.
    • (1994) Gene , vol.143 , pp. 55-59
    • Johanson, U.1    Hughes, D.2
  • 26
    • 0023035207 scopus 로고
    • Ribosomal genes in Escherichia coli
    • Lindahl L, Zengel J. 1986. Ribosomal genes in Escherichia coli. Annu Rev Genet 20:297-326.
    • (1986) Annu Rev Genet , vol.20 , pp. 297-326
    • Lindahl, L.1    Zengel, J.2
  • 27
    • 0023604801 scopus 로고
    • Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: An analysis of three mutants
    • Makosky P, Dahlberg A. 1987. Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: An analysis of three mutants. Biochimie 69:885-889.
    • (1987) Biochimie , vol.69 , pp. 885-889
    • Makosky, P.1    Dahlberg, A.2
  • 28
    • 0021873344 scopus 로고
    • Characterization of the lep operon of Escherichia coli: Identification of the promoter and the gene upstream of the signal peptidase I gene
    • March PE, Inouye M. 1985. Characterization of the lep operon of Escherichia coli: Identification of the promoter and the gene upstream of the signal peptidase I gene. J Biol Chem 260:7206-7213.
    • (1985) J Biol Chem , vol.260 , pp. 7206-7213
    • March, P.E.1    Inouye, M.2
  • 29
    • 0024458904 scopus 로고
    • Intermediate states in the movement of transfer RNA in the ribosome
    • Moazed D, Noller H. 1989. Intermediate states in the movement of transfer RNA in the ribosome. Nature 342:142-148.
    • (1989) Nature , vol.342 , pp. 142-148
    • Moazed, D.1    Noller, H.2
  • 30
    • 0023722010 scopus 로고
    • Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA
    • Moazed D, Robertson J, Noller H. 1988. Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA. Nature 334:362-364.
    • (1988) Nature , vol.334 , pp. 362-364
    • Moazed, D.1    Robertson, J.2    Noller, H.3
  • 31
    • 0027988206 scopus 로고
    • Mutations in helix 34 of Escherichia coli 16 S ribosomal RNA have multiple effects on ribosome function and synthesis
    • Moine H, Dahlberg A. 1994. Mutations in helix 34 of Escherichia coli 16 S ribosomal RNA have multiple effects on ribosome function and synthesis. J Mol Biol 243:402-412.
    • (1994) J Mol Biol , vol.243 , pp. 402-412
    • Moine, H.1    Dahlberg, A.2
  • 32
    • 0030774277 scopus 로고    scopus 로고
    • The ribosome-in-pieces: Binding of elongation factor EF-G to oligoribonucleotides that mimic the sarcin/ricin and thiostrepton domains of 23S ribosomal RNA
    • Munishkin A, Wool I. 1997. The ribosome-in-pieces: Binding of elongation factor EF-G to oligoribonucleotides that mimic the sarcin/ricin and thiostrepton domains of 23S ribosomal RNA. Proc Natl Acad Sci USA 94:12280-12284.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12280-12284
    • Munishkin, A.1    Wool, I.2
  • 34
    • 0021155247 scopus 로고
    • Regulation of the synthesis of ribosomes and ribosomal components
    • Nomura M, Gourse R, Baughman G. 1984. Regulation of the synthesis of ribosomes and ribosomal components. Annu Rev Biochem 53:75-117.
    • (1984) Annu Rev Biochem , vol.53 , pp. 75-117
    • Nomura, M.1    Gourse, R.2    Baughman, G.3
  • 35
    • 0032560490 scopus 로고    scopus 로고
    • Protein biosynthesis: Structural studies of the elongation cycle
    • Nyborg J, Liljas A. 1998. Protein biosynthesis: Structural studies of the elongation cycle. FEBS Lett 430:95-99.
    • (1998) FEBS Lett , vol.430 , pp. 95-99
    • Nyborg, J.1    Liljas, A.2
  • 37
    • 0027375408 scopus 로고
    • Mutations at U2555, a tRNA-protected base in 23S rRNA, affect translational fidelity
    • O'Connor M, Dahlberg A. 1993. Mutations at U2555, a tRNA-protected base in 23S rRNA, affect translational fidelity. Proc Natl Acad Sci USA 90:9214-9218.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9214-9218
    • O'Connor, M.1    Dahlberg, A.2
  • 38
    • 0026322432 scopus 로고
    • Interaction between 16S ribosomal RNA and ribosomal protein S12: Differential effects of paromomycin and streptomycin
    • O'Connor M, De Stasio E, Dahlberg A. 1991. Interaction between 16S ribosomal RNA and ribosomal protein S12: Differential effects of paromomycin and streptomycin. Biochimie 73:1493-1500.
    • (1991) Biochimie , vol.73 , pp. 1493-1500
    • O'Connor, M.1    De Stasio, E.2    Dahlberg, A.3
  • 39
    • 0014690239 scopus 로고
    • Studies on the formation of transfer ribonucleic acid-ribosome complexes
    • Pestka S. 1969. Studies on the formation of transfer ribonucleic acid-ribosome complexes. J Biol Chem 244:1533-1539.
    • (1969) J Biol Chem , vol.244 , pp. 1533-1539
    • Pestka, S.1
  • 40
    • 0020364218 scopus 로고
    • Covalent crosslinking of tRNA1Val to 16S RNA at the ribosomal P site: Identification of cross-linked residues
    • Prince JB, Taylor BH, Thurlow DL, Ofengand J, Zimmerman RA. 1982. Covalent crosslinking of tRNA1Val to 16S RNA at the ribosomal P site: Identification of cross-linked residues. Proc Natl Acad Sci USA 79:5450-5454.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 5450-5454
    • Prince, J.B.1    Taylor, B.H.2    Thurlow, D.L.3    Ofengand, J.4    Zimmerman, R.A.5
  • 41
    • 0015305465 scopus 로고
    • Ribosomes cannot interact simultaneously with elongation factors EF Tu and EF G
    • Richman N, Bodley J. 1972. Ribosomes cannot interact simultaneously with elongation factors EF Tu and EF G. Proc Natl Acad Sci USA 69:686-689.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 686-689
    • Richman, N.1    Bodley, J.2
  • 42
    • 0031028688 scopus 로고    scopus 로고
    • Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome
    • Rodnina M, Savelsbergh A, Katunin V, Wintermeyer W. 1997. Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature 305:37-41.
    • (1997) Nature , vol.305 , pp. 37-41
    • Rodnina, M.1    Savelsbergh, A.2    Katunin, V.3    Wintermeyer, W.4
  • 43
    • 0024271795 scopus 로고
    • Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli
    • Sigmund CD, Ettayebi M, Borden A, Morgan EA. 1988. Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli. Methods Enzymol 164:673-690.
    • (1988) Methods Enzymol , vol.164 , pp. 673-690
    • Sigmund, C.D.1    Ettayebi, M.2    Borden, A.3    Morgan, E.A.4
  • 45
    • 0025370161 scopus 로고
    • A single base mutation at position 2661 in E. coli ribosomal RNA affects the binding of ternary complex to the ribosome
    • Tapprich W, Dahlberg A. 1990. A single base mutation at position 2661 in E. coli ribosomal RNA affects the binding of ternary complex to the ribosome. EMBO J 9:2649-2665.
    • (1990) EMBO J , vol.9 , pp. 2649-2665
    • Tapprich, W.1    Dahlberg, A.2
  • 46
    • 0024297116 scopus 로고
    • Mutations within the decoding site of Escherichia coli 16S rRNA: Growth rate, impairment, lethality and intragenic suppression
    • Thomas C, Gregory R, Winslow G, Muto A, Zimmerman R. 1988. Mutations within the decoding site of Escherichia coli 16S rRNA: Growth rate, impairment, lethality and intragenic suppression. Nucleic Acids Res 76:8129-8146.
    • (1988) Nucleic Acids Res , vol.76 , pp. 8129-8146
    • Thomas, C.1    Gregory, R.2    Winslow, G.3    Muto, A.4    Zimmerman, R.5
  • 47
    • 0023689001 scopus 로고
    • Site-directed mutagenesis of Escherichia coli 23S ribosomal RNA at position 1067 within the GTP hydrolysis center
    • Thompson J, Cundliffe E, Dahlberg A. 1988. Site-directed mutagenesis of Escherichia coli 23S ribosomal RNA at position 1067 within the GTP hydrolysis center. J Mol Biol 203:457-465.
    • (1988) J Mol Biol , vol.203 , pp. 457-465
    • Thompson, J.1    Cundliffe, E.2    Dahlberg, A.3
  • 49
    • 0032498266 scopus 로고    scopus 로고
    • Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probing
    • Wilson K, Noller H. 1998a. Mapping the position of translational elongation factor EF-G in the ribosome by directed hydroxyl radical probing. Cell 92:131-139.
    • (1998) Cell , vol.92 , pp. 131-139
    • Wilson, K.1    Noller, H.2
  • 50
    • 0032488946 scopus 로고    scopus 로고
    • Molecular movement inside the translational engine
    • Wilson K, Noller H. 1998b. Molecular movement inside the translational engine. Cell 92:337-349.
    • (1998) Cell , vol.92 , pp. 337-349
    • Wilson, K.1    Noller, H.2


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