Adenovirus infections following haematopoietic cell transplantation: Is there a role for adoptive immunotherapy?

Bone Marrow Transplantation

Volumn 26, Issue 3, 2000, Pages 305-307

  Chakrabarti, S ^a   Collingham, K E ^a   Fegan, C D ^a   Pillay, D ^a   Milligan, D W ^a  

^a BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

Author keywords

Adenovirus; Donor lymphocyte infusion; Immunosuppression

Indexed keywords

CYCLOSPORIN A; METRONIDAZOLE;

ADENOVIRUS; ADOPTIVE IMMUNOTHERAPY; ADULT; ALLOTRANSPLANTATION; ARTICLE; CASE REPORT; DRUG WITHDRAWAL; FEMALE; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; LYMPHOCYTE; MALE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INFECTION;

EID: 0033860892     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1702508     Document Type: Article

References (11)

1. Shields AF, Hackman RC, Fife KH et al. Adenovirus infections in patients undergoing bone marrow transplantation. New Engl J Med 1985; 312: 529-533.
2. Flomenberg P, Babbitt J, Drobyski WR et al. Increased incidence of adenovirus disease in bone marrow transplant recipients. J Infect Dis 1994; 169: 775-781.
3. Blanke C, Clark C, Broun R et al. Evolving pathogens in allogeneic bone marrow transplantation: increased fatal adenoviral infections. Am J Med 1995; 99: 326-328.
4. Chakrabarti S, Collingham KE, Fegan C, Milligan DW. Fulminant adenovirus hepatitis following unrelated hone marrow transplantation: failure of intravenous ribavirin therapy. Bone Marrow Transplant 1999; 23: 1209-1211.
5. Rooney CM, Smith CA, Ng CYC et al. Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients. Blood 1998; 92: 1549-1555.
6. Hromas R, Cornetta K, Srour E et al. Donor leukocyte infusion as therapy of life-threatening adenoviral infections after T-cell-depleted hone marrow transplantation. Blood 1994; 84: 1689-1690.
7. Miyamoto T, Gondo H, Miyoshi Y et al. Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma. Br J Haematol 1998; 100: 348-350.
8. Childs R, Sanchez C, Engler H et al. High incidence of adenoand polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine. Bone Marrow Transplant 1998; 22: 889-893.
9. Flomenberg P, Piaskowski V, Truitt RL, Casper JT. Characterisation of human T cell responses to adenovirus. J Infect Dis 1995; 171: 1090-1096.
10. Flomenberg P, Piaskowski V, Truitt RL, Casper JT. Human adenovirus specific CD8+ T-cell responses are not inhibited by E3-19K in the presence of gamma Interferon. J Virol 1996; 70: 6314-6322.
11. Smith CA, Woodruff LS, Kitchingman GR, Rooney CM. Adenovirus-pulsed dendritic cells stimulate human virus-specitic T-cell responses in vitro. J Virol 1996; 70: 6733-6740.