Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3- hydroxylation in humans

Drug Metabolism and Disposition

Volumn 28, Issue 8, 2000, Pages 959-965

  Wang, J S ^a   Backman, J T ^a   Taavitsainen, P ^a   Neuvonen, P J ^a   Kivisto, K T ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 3A4; FURAFYLLINE; LIDOCAINE; MEPHENYTOIN; PYRIDINE; QUINIDINE; SULFAPHENAZOLE; TROLEANDOMYCIN;

ADULT; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG INHIBITION; DRUG LIVER LEVEL; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME KINETICS; FEMALE; HUMAN; HUMAN TISSUE; LIVER MICROSOME; MALE; PRIORITY JOURNAL;

ANTI-ARRHYTHMIA AGENTS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; HYDROXYLATION; ISOENZYMES; KINETICS; LIDOCAINE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; RECOMBINANT PROTEINS;

EID: 0033860013     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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