Interleukin-6 in the central nervous system;L'interleukine-6 dans le systeme nerveux central

Medecine/Sciences

Volumn 16, Issue 8-9, 2000, Pages 936-944

  Vallieres, L ^a   Rivest, S ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 6;

BRAIN INJURY; CENTRAL NERVOUS SYSTEM; HOMEOSTASIS; HOST RESISTANCE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNE RESPONSE; IMMUNOREACTIVITY; MAMMAL; REVIEW; SEPSIS; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; TISSUE REPAIR;

EID: 0033857562     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.4267/10608/1761     Document Type: Review

References (29)

1. How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli
2. Interleukin-6 is a needed proinflammatory cytokine in the prolonged neural activity and transcriptional activation of corticotropin-releasing factor during endotoxemia
3. Characterization of a recombinant murine interleukin-6: Assignment of disulfide bonds
4. Hematopoietin subfamily classification based on size, gene organisation and sequence homology
5. Influence of interleukin-6 on neural activity and transcription of the gene encoding corticotrophin-releasing factor in the rat brain: An effect depending upon the route of administration
6. Regulation of the genes encoding interleukin-6, its receptor, and gp130 in the rat brain in response to the immune activator lipopolysaccharide and the proinflammatory cytokine interleukin-1beta
7. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6
8. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain
9. An essential role of interleukin-1β in mediating NF-κB activity and COX-2 transcription in cells of the blood-brain barrier in response to systemic and localized inflammation, but not during endotoxemia
10. Regulation of the gene encoding tumor necrosis factor alpha (TNF-α) in the rat brain and pituitary in response to different models of systemic immune challenge
11. The bacterial endotoxin lipopolysaccharide has the ability to target tile brain in upregulating its membrane CD14 receptor within specific cellular populations
12. Neuronal activity and transcription of proinflammatory cytokines, IkappaBalpha, and iNOS in the mouse brain during acute endotoxemia and chronic infection with Trypanosoma brucei brucei
13. Induction and regulation of interleukin-6 gene expression in rat astrocytes
14. Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene
15. Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor
16. Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta
17. Involvement of CCAAT/enhancer-binding protein and nuclear factor-kappa B binding sites in interleukin-6 promote inhibition by estrogens
18. Isolation and characterization of the human gp130 promoter. Regulation by STATS
19. Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines
20. Activation of interleukin-6 gene expression through the NF-kappa B transcription factor
21. Interleukin-6 induction by tumor necrosis factor and interleukin-1 in human fibroblasts involves activation of a nuclear factor binding to a kappa B-like sequence
22. The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein
23. Ionizing radiation induces expression of interleukin 6 by human fibroblasts involving activation of nuclear factor-kappa B
24. Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF kappa B, and Sp1 transcription factors
25. Cross-talk between steroids and NF-kB: What language?
26. Cytokine signaling: Inhibitors keep cytokines in check
27. Effect of acute systemic inflammatory response and cytokines on the transcription of the genes encoding cyclooxygenase enzymes (COX-1 and COX-2) in the rat brain
28. Characterization of early cytokine responses and an interleukin (IL)-6- dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection
29. Pituitary cytokine and growth factor expression and action