Induction of functional CD154 (CD40 ligand) in neonatal T cells by cAMP-elevating agents

Immunology

Volumn 100, Issue 4, 2000, Pages 432-440

  Suarez A ^b   Mozo, L ^b   Gayo, A ^b   Simo A ^b   Gutierrez C ^a  

^a UNIVERSITY OF OVIEDO   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; CD69 ANTIGEN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 4; IONOMYCIN; MESSENGER RNA;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN INDUCTION; T LYMPHOCYTE; TH2 CELL;

ADULT; AGING; ANTIGENS, CD40; BUCLADESINE; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELL CULTURE TECHNIQUES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOKINES; FETAL BLOOD; HUMANS; IMMUNOPHENOTYPING; INFANT, NEWBORN; IONOMYCIN; LIGANDS; MEMBRANE GLYCOPROTEINS;

EID: 0033854062     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2000.00051.x     Document Type: Article

References (36)

1. 1. Kovarik J. & Siegrist C.A. (1998) Immunity in early life. Immunol Today 19, 150.
2. 2. Paloczi K. (1999) Immunophenotypic and functional characterization of human umbilical cord blood mononuclear cells. Leukemia 13 (Suppl. 1), 87.
3. 3. Chalmers I.M.H., Janossy G., Contreras M. & Navarrete C. (1998) Intracellular cytokine profile of cord and adult blood lymphocytes. Blood 92, 11.
4. 4. Barbey C., Irion O., Helg C. et al. (1998) Characterisation of the cytotoxic alloresponse of cord blood. Bone Marrow Transplantation 22 (Suppl. 1), S26.
5. 5. Borrione P., Peola S., Mariani S. et al. (1999) CD38 stimulation lowers the activation threshold and enhances the alloreactivity of cord blood T cells by activating the phosphatidylinositol 3-kinase pathway and inducing CD73 expression. J Immunol 162, 6238.
6. 6. Sato K., Naygayama H. & Takahashi T.A. (1999) Aberrant CD3-and CD28-mediated signaling events in cord blood T cells are associated with dysfunctional regulation of Fas Ligand-mediated cytotoxicity. J Immunol 162, 4464.
7. 7. Kurtzberg J., Laughlin M., Graham M.L. et al. (1996) Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med 335, 157.
8. 8. Rubinstein P., Carrier C., Scaradavou A. et al. (1998) Outcomes among 562 recipients of placental-blood transplants from unrelated donors. N Engl J Med 339, 1565.
9. 9. Gluckman E., Rocha V., Boyer-Chammard A. et al. (1997) Outcome of cord-blood transplantation from related and unrelated donors. Eurocord Transplant Group and the European Blood and Marrow Transplantion Group. N Engl J Med 337, 373.
10. 10. Hollenbaugh D., Ochs H.D. & Noelle R.J. (1994) The role of CD40 and its ligand in the regulation of the immune response. Immunol Rev 138, 25.
11. 11. Ramesh N., Seki M., Notarangelo L.D. & Geha R.S. (1998) The Hyper-Igm (HIM) Syndrome. Springer Semin Immunopathol 19, 383 .
12. 12. Grewal I.S. & Flavell R.A. (1998) CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 16, 1 11.
13. 13. Van Essen D., Kikutani H. & Gray D. (1995) CD40 ligand-transduced co-stimulation of T cells in the development of helper function. Nature 378, 620.
14. 14. Cella M., Scheidegger D., Palmer-Lehmann K., Lane P., Lanzavecchia A. & Alber G. (1996) Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Immunol 184, 747.
15. 15. Peng X., Kasran A., Warmerdam P.A.M., De Boer M. & Ceuppens J.L. (1996) Accessory signaling by CD40 for T cell activation: induction of Th1 and Th2 cytokines and synergy with interleukin-12 for interferon-γ production. Eur J Immunol 26, 1621.
16. 16. De vita L., Accapezzato D., Mangino G. et al. (1998) Defective Th1 and Th2 cytokine synthesis in the T-T cell presentation model for lack of CD40/CD40 ligand interaction. Eur J Immunol 28, 3552.
17. 17. Yang Y. & Wilson J.M. (1996) CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40. Science 273, 1862.
18. 18. Poudrier J., Van Essen D., Morales-Alcelay S., Leanderson T., Bergthorsdottir S. & Gray D. (1998) CD40 ligand signals optimize T helper cell cytokine production: role in Th2 development and induction of germinal centers. Eur J Immunol 28, 3371.
19. 19. Durandy A., De Saint Basile G., Lisowska-Grospierre B. et al. (1995) Undetectable CD40 ligand expression on T cells and low B cell responses to CD40 binding agonist in human newborns. J Immunol 154, 1560.
20. 20. Nonoyama S., Penix L.A., Edwards C.P. et al. (1995) Diminished expression of CD40 ligand by activated neonatal T cells. J Clin Invest 95, 66.
21. 21. Splawski J.B., Nishioka J., Nishioka Y. & Lipsky P.E. (1996) CD40 ligand is expressed and functional on activated neonatal T cells. J Immunol 156, 119.
22. 22. Suárez A., Mozo L., Gayo A., Zamorano J. & Gutiérrez C. (1997) Requirement of a second signal via protein kinase C or protein kinase A for maximal expression of CD40 ligand. Involvement of transcriptional and posttranscriptional mechanisms. Eur J Immunol 27, 2822.
23. 23. Wingett D.G., Forcier K. & Nielson C.P. (1999) Regulation of CD40L expression by cyclic AMP: contrasting proinflammatory and inhibitory actions. Cellular Immunol 192, 203.
24. 2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 150, 5321.
25. 25. Fedyk E.R., Adawi A., Looney R.J. & Phipps R.P. (1996) Regulation of IgE and cytokine production by cAMP: implications for extrinsic asthma. Clin Immunol Immunopathol 81, 101.
26. 26. Benbernou N., Esnault S., Shin H.C., Fekkar H. & Guenounou M. (1997) Differential regulation of IFN-gamma, IL-10 and inducible nitric oxide synthase in human T cells by cyclic AMP-dependent signal transduction pathway. Immunology 91, 361.
27. 27. Kolenko V., Rayman P., Roy B. et al. (1999) Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway. Blood 93, 2308.
28. 28. Chomczynski P. & Sacchi N. (1987) Single-step method of RNA isolation by cid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162, 156.
29. 29. Sambrook J., Fritsch E.F. & Maniatis T. (1989). Molecular Cloning: a Laboratory Manual, Cold Spring Harbor Laboratory Press. New York.
30. 30. Ford G.S., Barnhart B., Shone S. & Covey L.R. (1999) Regulation of CD154 (CD40 ligand) mRNA stability during T cell activation. J Immunol 162, 4037.
31. 31. Hilkens C.M.U., Kalinski P., De Boer M. & Kapsenberg M.L. (1997) Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype. Blood 90, 1920.
32. 32. Elenkov I.J., Webster E., Papanicolau D.A., Fleisher T.A., Chrousos G.P. & Wilder R.L. (1998) Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors. J Immunol 161, 2586.
33. 33. Sacks G., Sargent I. & Redman C. (1999) An innate view of human pregnancy. Immunol Today 20, 114.
34. 34. Fu X., Backstrom T. & Ulmsten U. (1998) Progesterone increases cAMP release and accumulation in isolated term human myometrium. Gynecol Obstet Invest 45, 242.
35. 2, promote type 2 cytokine production in maturing human naive T helper cells. J Immunol 159, 28.
36. 36. Raghupathy R. (1997) Th1-type immunity is incompatible with successful pregnancy. Immunol Today 18, 479.