Kynapcin-12, a new p-terphenyl derivative from Polyozellus multiplex, inhibits prolyl endopeptidase

Journal of Antibiotics

Volumn 53, Issue 7, 2000, Pages 714-719

  Lee, H J ^a   Rhee, I K ^a   Lee, K B ^a   Yoo, I D ^a   Song, K S ^a  

^a Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; CHYMOTRYPSIN; ELASTASE; KYNAPCIN 12; POLYOZELLIN; PROLYL ENDOPEPTIDASE; PROLYL ENDOPEPTIDASE INHIBITOR; TERPHENYL DERIVATIVE; THELEPHORIC ACID; TRYPSIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ENZYME ACTIVITY; EXTRACTION; MUSHROOM; NEUROTOXICITY; NONHUMAN; NOTE; PRIORITY JOURNAL;

POLYOZELLUS MULTIPLEX;

EID: 0033853405     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.714     Document Type: Note

References (28)

1. Role of the β-amyloid protein in Alzheimer's disease
2. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
3. 2+ homeostasis in Alzheimer's disease
4. Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease
5. Identification of a putative amyloid A4-generating enzyme as a prolyl endopeptidase
6. Proline-dependent structural and biological properties of peptides and proteins
7. cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue
8. Post-proline cleaving enzyme (prolyl endopeptidase) from bovine brain
9. Deficiency of kallikrein-like enzyme activities in cerebral tissue of patients with Alzheimer's disease
10. New prolyl endopeptidase inhibitors: In vitro and in vivo activities of azabicyclo[2.2.2]octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives
11. Specific inhibitors for prolyl endopeptidase and their anti-amnesic effect
12. Thelephoric acid and kynapcin-9 from mushroom Polyozellus multiflex inhibit prolyl endopeptidase in vitro
13. Polyozellin, a new inhibitor of prolyl endopeptidase from Polyozellus multiflex
14. Fungus pigments IX. Some further constituents of Hydnum aurantiacum Batsch
15. Previously unreported p-terphenyl derivatives with antibiotic properties from the fruiting bodies of Sarcodon leucopus (Basidiomycetes). A two-dimensional nuclear magnetic resonance study
16. Colorimetric methods for the direct determination of p-aminosalicylic acid in the presence of isoniazid
17. Synthesis of prolyl endopeptidase inhibitors and evaluation of their structure-activity relationships: In vitro inhibition of prolyl endopeptidase from canine brain
18. Staurosporin, a prolyl endopeptidase inhibitor
19. Poststatin, a new inhibitor of prolyl endopeptidase produced by Streptomyces viridochromogenes MH534-30F3. I. Taxonomy, production, isolation, physico-chemical properties and biological activities
20. Eurystatins A and B. New prolyl endopeptidase inhibitors. I. Taxonomy, production, isolation and biological activities
21. Lipohexin, a new inhibitor of prolyl endopeptidase from Moeszia lindtneri (HKI-0054) and Paecilomyces sp. (HKI-0055; HKI-0096). I. Screening, isolation and structure elucidation
22. Propeptin, a new inhibitor of prolyl endopeptidase produced by Microbispora. I. Fermentation, isolation and biological properties
23. SNA-8073-B, a new isotetracenone antibiotic inhibits prolyl endopeptidase. I. Fermentation, isolation and biological properties
24. Prolyl endopeptidase inhibitors from Caryophylli Flos
25. Prolyl endopeptidase inhibitors from the underground part of Rhodiola sacra S. H. Fu
26. Slow tight-binding of prolyl endopeptidase by benzyloxy-carbonyl-prolyl-prolinal
27. Proline-specific endopeptidase from Flavobacterium. Purification and properties
28. Lipid peroxidation inhibitors from Polyozellus multiflex