Current status and future perspectives of DNA vaccine delivery by attenuated intracellular bacteria

Archivum Immunologiae et Therapiae Experimentalis

Volumn 48, Issue 3, 2000, Pages 177-182

  Dietrich, Guido ^a,b  

^a Chiron Behring GmbH & Co   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Attenuated intracellular bacteria; Delivery; DNA vaccines

Indexed keywords

BETA GALACTOSIDASE; DIAMINOPIMELIC ACID; DNA VACCINE; HEMOLYSIN; HYBRID PROTEIN; LISTERIOLYSIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; PLASMID DNA; VIRUS NUCLEOPROTEIN;

ANTIGEN PRESENTING CELL; DRUG DELIVERY SYSTEM; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IMMUNE RESPONSE; NONHUMAN; REVIEW; VACCINATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; BACTERIA; GENETIC VECTORS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; LISTERIA MONOCYTOGENES; SALMONELLA TYPHIMURIUM; VACCINES, DNA;

EID: 0033852437     PISSN: 0004069X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (28)

1. BANCHERAU J. and STEINMAN R. (1998): Dendritic cells and the control of immunity. Nature, 392, 245-252.
2. CATIC A., D ETRICH G., GENTSCHEV I., GOEBEL W., KAUFMANN S. H. E. and HESS J. (1999): Introduction of protein or DNA delivered via recombinant Salmonella typhimurium into the major histocompatibility complex class I presentation pathway of macrophages. Microbes Infect., 2, 113-121.
3. CONDON C., WATKINS S. C., CELLUZZI C. M., THOMPSON K. and FALO L. D. JR. (1996): DNA-based immunization by in vivo transfection of dendritic cells. Nat. Med., 2, 1122-1128.
4. CORK M., LEE D. J., CARSON D. A. and TIGHE H. (1996): Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J. Exp. Med., 184, 1555-1560.
5. COURVALIN P., GOUSSARD S. and GRILLOT-COURVALIN C. (1995): Gene transfer from bacteria to mammalian cells. CR Acad. Sci., 318, 1202-1207.
6. DARJI A., GUZMAN C. A., GERSTEL B., WACHHOLZ P., TIMMIS K. N., WEHLAND J., CHAKRABORTY T. and WEISS S. (1997): Oral somatic transgene vaccination using attenuated S. typhimurium. Cell, 91, 765-775.
7. DAVIS H. L., BRAZOLOT-MILLAN C. L. and WATKINS S. C. (1997): Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA. Gene Ther., 4, 181-188.
8. DECK R. R., DEWITT C. M., DONNELLY J. J., LIU M. A. and ULMER J. B. (1997): Characterization of humoral immune responses induced by an influenza hemagglutinin DNA vaccine. Vaccine, 15, 71-78.
9. DIETRICH G., BUBERT A., GENTSCHEV I., SOKOLOVIC Z., SIMM A., CATIC A., KAUFMANN S. H. E., HESS J., SZALAY A. A. and GOEBEL W. (1998): Delivery of antigen-encoding plasmid DNA into the cytosol of macrophages by attenuated suicide Listeria monocytogenes. Nat. Biotechnol., 16, 181-185.
10. DOE B., SELBY M., BARNETT S., BAENZIGER J. and WALKER C. M. (1996): Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc. Natl. Acad. Sci. USA, 93, 8578-8583.
11. DONNELLY J. J., ULMER J. B., SHIVER J. W. and LIU M. A. (1997): DNA. Vaccines. Ann. Rev. Immunol., 15, 617-648.
12. FENNELLY G. J., KHAN S. A., ABADI M. A., WILD T. F. and BLOOM B. R. (1999): Mucosal DNA immunization against measles with a highly attenuated S. flexneri vector. J. Immunol., 162, 1603-1610.
13. FYNAN E. F., WEBSTER R. G., FULLER D. H., HAYNES J. R., SANTORO J. C. and ROBINSON H. L. (1993): DNA vaccines: protective immunizations by parenteral, mucosal and gene-gun inoculations. Proc. Natl. Acad. Sci. USA, 90, 1478-1482.
14. GENTSCHEV I., SOKOLOVIC Z., MOLLENKOPF H.-J., DEMUTH A., HESS J., KAUFMANN S. H. E., KROHNE G. F. and GOEBEL W. (1995): Salmonella secreting active listeriolysin changes its intracellular localization. Infect. Immun., 63, 4202-4205.
15. GRILLOT-COURVALIN C., GOUSSARD S., HUETZ F., OJCIUS D. M. and COURVALIN P. (1998): Functional gene transfer from intracellular bacteria to mammalian cells. Nat. Biotechnol., 16, 862-866.
16. HESS J., GENTSCHEV I., MIKO D., WEIZEL M., LADEL C., GOEBEL W. and KAUFMANN S. H. E. (1996): Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis. Proc. Natl. Acad Sci. USA, 93, 1458-1463.
17. HOHLFELD R. and ENGEL A. G. (1994): The immunobiology of muscle. Immunol. Today, 15, 269-273.
18. KAUFMANN S. H. E. (1998): Immunity to intracellular bacteria. In PAUL W. E.: Fundamental immunology. Lippincott-Raven Ltd., New York, 1335-1371.
19. KOVACSOVICS-BANKOWSKY M. and ROCK K. L. (1995): A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science, 267, 243-246.
20. PAGLIA P., MEDINA E., ARIOLI I., GUZMAN C. A. and COLOMBO M. P. (1998): Gene transfer in dendritic cells, induced by oral DNA vaccination with Salmonella typhimurium, results in protective immunity against a murine fibrosarcoma. Blood, 92, 3172-3176.
21. PAMER E. G., HARTY T. J. and BEVAN M. J. (1991): Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes. Nature, 353, 852-855.
22. PFEIFER J. D., WICK M. J., ROBERTS R. L., FINDLAY K., NORMARK S. J. and HARDING C. V. (1993): Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature, 361, 359-362.
23. PORTNOY D. A., CHAKRABORTY T., GOEBEL W. and COSSART P. (1992): Molecular determinants of Listeria monocytogenes pathogenesis. Infect. Immun., 60, 1263-1267.
24. POWELL R. J., LEWIS G. K. and HONE D. M. (1996): Introduc-tion of eukaryotic expression cassettes into animal cells using a bacterial vector delivery system. In Vaccines 96: Molecular approaches to the control of infectious disease. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 183-187.
25. SIZEMORE D. R., BRANSTROM A. A. and SADOFF J. C. (1995): Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization. Science, 270, 299-302.
26. SIZEMORE D. R., BRANSTROM A. A. and SADOFF J. C. (1997): Attenuated bacteria as a DNA delivery vehicle for DNA-mediated immunization. Vaccine, 15, 804-807.
27. TORRES C. A. T., IWASAKI A., BARBER B. H. and ROBINSON H. L. (1997): Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations. J. Immunol., 158, 4529-4532.
28. ULMER J. B., DECK R. R., DEWITT C. M., DONNELLY J. J. and LIU M. A. (1996): Generation of MHC class I restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells. Immunology, 89, 56-67.