Paracellular solute transport: More than just a leak?

Current Opinion in Nephrology and Hypertension

Volumn 9, Issue 5, 2000, Pages 513-515

  Yu, Alan S L ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; OCCLUDIN;

CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELL MEMBRANE TRANSPORT; CLINICAL PATHWAY; EDITORIAL; KIDNEY DISEASE; KIDNEY TUBULE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION;

BIOLOGICAL TRANSPORT, ACTIVE; CELL COMMUNICATION; CELL MEMBRANE PERMEABILITY; HUMANS; MEMBRANE PROTEINS; TIGHT JUNCTIONS;

EID: 0033849894     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041552-200009000-00009     Document Type: Editorial

References (29)

1. The molecular basis of solute transport
2. Molecular structure and assembly of the tight junction
3. Transmembrane proteins in the tight junction barrier
4. Fracture faces of zonulae oocludentes from 'tight' and 'leaky' epithelia
5. Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens
6. Occludin: A novel integral membrane protein localizing at tight junctions
7. Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes
8. Occludin confers adhesiveness when expressed in fibroblasts
9. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
10. Occludin is a functional component of the tight junction
11. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos
12. A synthetic peptide corresponding to the extracellular domain of oocludin perturbs the tight junction permeability barrier
13. A dominant mutant of occludin disrupts tight junction structure and function
14. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
15. Claudin-1 and -2 Novel integral membrane proteins localizing at tight junctions with no sequence similarity to oocludin
16. Claudin-1 contributes to the epithelial barrier function in MDCK cells
17. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
18. Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis
19. Occludin and claudins in tight-junction strands: Leading or supporting players?
20. 2+ resorption
21. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits oocludin in fibroblasts
22. Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions
23. Manner of interaction of heterogeneous claudin species within and between tight junction strands
24. CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice
25. Disturbances of magnesium metabolism
26. Control of NaCl transport in the thick ascending limb
27. Hypomagnesemia due to renal disease of unknown etiology
28. Renal magnesium and phosphate wastage in a patient with hypercalciuria and nephrocalcinosis: Effect of oral phosphorus and magnesium supplements
29. Paracellular channels!