Pumpkin-seed oil modulates the effect of felodipine and captopril in spontaneously hypertensive rats

Pharmacological Research

Volumn 41, Issue 5, 2000, Pages 555-563

  Zuhair, Hana Al ^a   Abd El Fattah, Amal A ^a   El Sayed, Moushira Ibrahim ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Captopril; Felodipine; Pumpkin seed oil; Spontaneously hypertensive rat

Indexed keywords

CAPTOPRIL; FELODIPINE; NATURAL PRODUCT; PEPON; PUMPKIN SEED OIL; UNCLASSIFIED DRUG; VEGETABLE OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; HYPERTENSION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

EID: 0033848162     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.1999.0622     Document Type: Article

References (42)

1. Free radicals, exercise and antioxidant supplementation
2. The effect of ryanodine on oxygen free radical-induced dysfunction of cardiac sarcoplasmic reticulum
3. Oxidative stress in the Dahl hypertensive rat
4. Role of oxygen-derived free radicals in acute angiotensin II-induced hypertensive vascular disease in the rat
5. Membrane Fluidity as a genetic marker of hypertension
6. Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats
7. Vitamin C and blood pressure
8. Antioxidants show an anti-hypertensive effect in diabetic and hypertensive subjects
9. Evaluation of the ability of the angiotensin-converting enzyme inhibitor captopril to scavenge reactive oxygen species
10. Angiotensin-converting enzyme inhibition alters nitric oxide and superoxide release in normotensive and hypertensive rats
11. The evolving role of calcium channel blocker in the treatment of angina pectoris: Focus on felodipine
12. Another possibility in treatment of hyperlipidemia with peponen of natural active substance
13. Analytical standardization of peponen
14. Felodipine-another calcium channel blocker for hypertension
15. Converting-enzyme inhibitors in the treatment of hypertension
16. Efficacy of simvastatin and pumpkin-seed oil in the management of dietary-induced hypercholesterolemia
17. Intracellular and extracellular sulph-hydryl levels in rheumatoid arthritis
18. Improved method for the determination of blood glutathione
19. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test
20. The estimation of red cell superoxide dismutase activity
21. The quantitative and qualitative characterization of erythrocyte glutathione peroxidase
22. Comparative study of superoxide dismutase, catalase and glutathione peroxidase levels in erythrocyte of different animals
23. Protein measurement with the folin phenol reagent
24. The cardiovascular actions of the volatile oil of the black seed (Nigella sativa) in rats: Elucidation of the mechanism of action
25. Does superoxide underlie the pathogenesis of hypertension?
26. Direct in situ measurement of nitric oxide in mesenteric resistance arteries. Increased decomposition by superoxide in hypertension
27. Endothelial dysfunction and hypertension
28. Role of oxygen in the cellular damage induced by reoxygenation of hypoxic heart
29. Glutathione peroxidase, superoxide dismutase and catalase inactivation by peroxides and oxygen derived free radicals
30. Nitric oxide and superoxide anions in vascular reactivity of renovascular hypertensive rats
31. Decreased superoxide dismutase activity and increased superoxide anion production in cardiac hypertrophy of spontaneously hypertensive rats
32. Aortic glutathione-related antioxidant defences in rabbits subjected to suprarenal aortic coarctation hypertension
33. Reduction of insulin resistance attenuates the development of hypertension in sucrose-fed SHR
34. Enhanced inhibition by melatonin of α-adrenoceptor-induced aortic contraction and inositol phosphate production in vascular smooth muscle cells from spontaneously hypertensive rats
35. Lipid peroxide, phospholipids, glutathione levels and superoxide dismutase activity in rat brain after ischemia: Effect of ginkgo biloba extract
36. Antihypertensive agents and the drug therapy of hypertension
37. Captopril induced increase in coronary flow an SH-dependent effect on arachidonic acid metabolism?
38. Captopril prevents the oxidative damage to proteins after renal ischemia reperfusion injury: Role of endothelin-1
39. Reversal of cardiac hypertrophy in humans
40. Host biochemical defense mechanisms against prooxidants
41. Epidemiological and intervention studies on the effect of marine polyunsaturated fatty acids on blood pressure
42. Carotenoids as cellular antioxidants