Sublytic complement injury does not activate NF-κB, or induce mitogenesis in rat mesangial cells

Experimental Nephrology

Volumn 8, Issue 4-5, 2000, Pages 291-298

  Mudge, S J ^a   McRae, J L ^a   Auwardt, R B ^a   Murphy, B F ^a   Chen, C G ^a   Power, D A ^a   Mudge, Stuart ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

Complement; Mesangial cell; Mitogenesis; NF B; Sublytic

Indexed keywords

ANTIBODY; CHROMIUM; COMPLEMENT; COMPLEMENT MEMBRANE ATTACK COMPLEX; GROWTH FACTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; SUPEROXIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; IMMUNOGLOBULIN A NEPHROPATHY; MESANGIUM CELL; MITOGENESIS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT;

EID: 0033848135     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: 10.1159/000020681     Document Type: Article

References (26)

1. Murphy BF, D'Apice AJF: Identification of the components of glomerular immune deposits using monoclonal antibodies. Pathology 1988; 20:130-136.
2. Murphy BF, Davies DJ, Morrow W, d'Apice AJF: Localization of terminal complement complexes. S-protein and SP-40,40 in renal biopsies. Pathology 1989;21:275-278.
3. Couser WG: Pathogenesis of glomerulonephritis. Kidney Int 1993;44:S19-S26.
4. Brandt J, Pippin J, Schulze M, Hansch GM, Alpers CE, Johnson RJ, Gordon K, Couser WG: Role of the complement membrane attack complex (C5b-9) in mediating experimental mesangioproliferative glomerulonephritis. Kidney Int 1996;49:335-343.
5. Kopp E, Ghosh S: NF-κB and re1 proteins in innate immunity. Adv Immunol 1995;58:1-27.
6. Thanos D, Maniatis T: NF-κB: A lesson in family values. Cell 1995;80:529-532.
7. Baeuerle PA, Baichwal VR: NF-κB as frequent target for immunosuppressive and anti-inflammatory molecules. Adv Immunol 1997;65: 111-137.
8. Yoshioka K, Takemura T, Murakami K, Okada M, Yagi K, Miyazato H, Matushima K, Maki S: In situ expression of cytokines in IgA nephritis. Kidney Int 1993;44:825-833.
9. Rovin BH, Rumancik M, Tan L, Dickerson J: Glomerular expression of monocyte chemoattractant protein-1 in experimental and human glomerulonephritis. Lab Invest 1994;71:536-542.
10. Dal Canton A: Adhesion molecules in renal disease. Kidney Int 1995;48:1687-1696.
11. Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T: Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers. FASEB 1995;9:899-909.
12. Rovin BH, Dickerson JA, Tan LC, Hebert CA: Activation of nuclear factor-κB correlates with MCP-1 expression by human mesangial cells. Kidney Int 1995;48:1263-1271.
13. Wenzel U, Schneider A, Valente AJ, Abboud HE, Thaiss F, Helmchen UM, Stahl RAK: Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis. Kidney Int 1997;51:770-776.
14. Stahl RAK, Thaiss F, Disser M, Helmchen U, Hora K, Schlondorff D: Increased expression of monocyte chemattractant protein-1 in anti-thymocyte antibody-induced glomerulonephritis. Kidney Int 1993;44:1036-1047.
15. Polihronis M, Murphy BF, Pearse MJ, Power DA: Heparin binding epidermal growth factor-like growth factor, an immediate-early gene for mesangial cells, is up-regulated in the Thy1.1 model. Exp Nephrol 1996;4:271-278.
16. Adler S, Baker PJ, Johnson RJ, Ochi RF, Pritzl P, Couser WG: Complement membrane attack complex stimulates production of reactive oxygen metabolites by cultured rat mesangial cells. J Clin Invest 1986;77:762-767.
17. Halperin JA, Taratuska A, Nicholson-Weller A: Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells. J Clin Invest 1993;91:1974-1978.
18. Chen CG, Malliaros J, Katerelos M, d'Apice AJ, Pearse MJ: Inhibition of NF-κB activation by a dominant-negative mutant of IκBα. Mol Immunol 1996;33:57-61.
19. Tewari M, Mohn KL, Yue FE, Taub R: Sequence of rat RL/IF-1 encoding an IκB, and comparison with related proteins containing notch-like repeats [corrected; published errata appear in Nucleic Acids Res 1992;20:2624 and 1992;20:2931]. Nucleic Acids Res 1992;20: 607.
20. Martin T, Cardarelli PM, Parry GCN, Felts KA, Cobb RR: Cytokine induction of monocyte chemoattractant protein-1 gene expression in human endothelial cells depends on the cooperative action of NF-κB and AP-1. Eur J Immunol 1997;27:1091-1097.
21. Ueda A, Okuda K, Ohno S, Shirai A, Igarashi T, Matsunaga K, Fukushima J, Kawamoto S, Ishigatsubo Y, Okubo T: NF-κB and Sp1 regulate transcription of the human monocytc chemoattractant protein-1 gene. J Immunol 1994; 153:2052-2063.
22. Kilgore KS, Schmid E, Shanley TP, Flory CM, Maheswari V, Tramontini NL, Cohen H, Ward PA, Friedl HP, Warren JS: Sublytic concentrations of the membrane attack complex of complement induce endothelial interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-κB activation. Am J Pathol 1997;150:2019-2031.
23. Nangaku M, Quigg RJ, Shankland SJ, Okada N, Johnson RJ, Couser WG: Overexpression of Crry protects mesangial cells from complement-mediated injury. J Am Soc Nephrol 1997;8:223-233.
24. Satriano J, Schlondorff D: Activation and attenuation of transcription factor NF-κB in mouse glomerular mesangial cells in response to tumour necrosis factor-α, immunoglobulin G, and adenosine 3′:5′-cyclic monophosphate. J Clin Invest 1994;94:1629-1636.
25. Satriano JA, Shuldiner M, Hora K, Xing Y, Shan Z, Schlondorff D: Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor. CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G: Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase. J Clin Invest 1993;92:1564-1571.
26. Duque N, Gomez-Guerrero C, Egido J: Interaction of IgA with Fcα receptors of human mesangial cells activates transcription factor-κB and induced expression and synthesis of monocyte chemoattractant protein-1, IL-8 and IFN-inducible protein 10. J Immunol 1997; 159:3474-3482.