Influence of enalapril on the endothelial function of DOCA-salt hypertensive rats

General Pharmacology

Volumn 34, Issue 2, 2000, Pages 117-125

  Nunes, V W ^a   Fortes, Z B ^a   Nigro, D ^a   Carvalho, M H C ^a   Zorn, T M T ^b   Scivoletto, R ^a  

^a Nephrology Division   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

DOCA salt hypertension; Enalapril; Vascular reactivity

Indexed keywords

ACETYLCHOLINE; DEOXYCORTICOSTERONE ACETATE; ENALAPRIL; HYDRALAZINE; NITROPRUSSIDE SODIUM; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; HYPERTENSION; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME; TUNICA MEDIA; VASODILATATION;

ACETYLCHOLINE; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA, THORACIC; BLOOD PRESSURE; DESOXYCORTICOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENALAPRIL; ENDOTHELIUM, VASCULAR; HYPERTENSION; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NITROPRUSSIDE; NOREPINEPHRINE; POTASSIUM CHLORIDE; RATS; RATS, WISTAR; SODIUM CHLORIDE; VASOCONSTRICTOR AGENTS; VASODILATOR AGENTS;

EID: 0033847082     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(00)00053-7     Document Type: Article

References (33)

1. Arvola P., Ruskoaho H., Wuorela H., Pekki A., Vaspastolo H., Pörsti I. Quinapril treatment and arterial smooth muscle response in spontaneously hypertensive rats. Br J Pharmac. 108:1993;980-990.
2. Bossaler C., Auch-Schwelk W., Weber F., Götze S., Gräfe M., Graf K., Fleck E. Endothelium-dependent relaxations are augmented in rats chronically treated with the angiotensin-converting enzyme inhibitor enalapril. J Cardiovasc Pharmac. 20(suppl. 9):1992;591-595.
3. Carvalho M.H.C., Scivoletto R., Fortes Z.B., Nigro D., Cordellini S. Reactivity of aorta and mesenteric microvessels to drugs in spontaneously hypertensive rats. role of the endothelium J Hypertens. 5:1987;377-382.
4. 2 in the altered microvascular reactivity in two-kidney, one-clip hypertension. Endothelium. 5:1997;167-178.
5. Chen K., Zhang X., Dunham E.W., Zimmerman B.G. Kinin-mediated antihypertensive effect of captopril in deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 27:1996;85-89.
6. Clozel M., Kuhn H., Hefti F. Effects of angiotensin converting enzyme inhibitors and of hydralazine on endothelial function in hypertensive rats. Hypertension. 16:1990;532-540.
7. Cordellini S., Carvalho M.H.C., Scivoletto R., Fortes Z.B., Nigro D. Indirect evidence for an endothelium-derived contracting factor release in aorta of deoxycorticosterone acetate-salt hypertensive rats. J Hypertens. 8:1990;53-60.
8. Cuman R.K.N., Nigro D., Carvalho M.H.C., Scivoletto R., Fortes Z.B. Influence of hydralazine treatment on the vascular reactivity of DOCA-salt hypertensive rats. Endothelium. 2:1994;105-111.
9. Furchgott R., Zawadzki J.V. The obligatory role of endothelial cells in relaxation of arterial smooth muscle by acetylcholine. Nature. 288:1980;373-376.
10. Gohlke P., Lambert V., Kuwer I., Bartenbach S., Schenell A., Linz W., Scholkens B.A., Wiemer G., Unger T. Long-term low dose angiotensin converting enzyme inhibitors treatment increases vascular cyclic guanosine 3′,5′-monophosphate. Hypertension. 22:1993;682-687. a.
11. Gohlke P., Lambert V., Kuwer I., Bartenbach S., Schenell A., Unger T. Vascular remodeling in systemic hypertension. Am J Cardiol. 71:1993;2E-7E. b.
12. Hirooka Y., Imaizumi T., Masaki H., Ando S., Harada S., Momohara M., Takeshita A. Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients. Hypertension. 20:1992;175-180.
13. 2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat. Hypertension. 15:1990;475-482.
14. Katusic, Z.S., Shepherd, J.T., 1991. Endothelium-derived vasoactive factors II: endothelium-dependent contraction. Hypertension 18(suppl. III),III-86-III-92.
15. w-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats. J Hypertension. 14:1996;1331-1339.
16. Lüscher T.F., Vanhoutte P.M. Endothelium-dependent contraction to acetylcholine in the aorta of spontaneously hypertensive rat. Hypertension. 8:1986;344-348.
17. Lüscher T.F., Raij L., Vanhoutte P. Endothelium-dependent vascular response in normotensive and hypertensive Dahl rats. Hypertension. 9:1987;157-163.
18. Madeddu P., Anania V., Papaglia P.P., Demontis M.P., Veroni M.V., Fattaccio M.C., Glorioso N. Chronic kinin receptor blockade induces hypertension in desoxycorticosterone-treated rats. Br J Pharmac. 108:1993;651-657.
19. Majima M., Katori M., Hanazuka M., Mizogami S., Nakano T., Nakao Y., Mikami R., Uryu H., Okamura R., Mohsin S.S.J., Oh-Ishi S. Suppression of rat deoxycorticosterone-salt hypertension by kallikrein-kinin system. Hypertension. 17:1991;806-813.
20. Mombouli J.V., Illiano S., Nagao T., Scott-Burden T., Vanhoutte P.M. Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin I converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxings and hyperpolarizing factors. Cir Res. 71:1992;137-144.
21. Naitoh M., Suzuki H., Arakawa K., Matsumoto A., Ichihara A., Matsuda H., Kubota E., Murakami M., Nakamoto H., Saruta T. Role of kinin and renal ANG II blockade in acute effects of ACE inhibitors in low-renin hypertension. Am J Physiol. 272(Part 2):1997;H679-H687.
22. Nigro D., Fortes Z.B., Carvalho M.H.C., Scivoletto R. Chronic but not acute treatment with hydralazine reverses the decreased endothelium-dependent responses in spontaneously hypertensive rats. Clin Exp Hypertens. 9:1989;573-586.
23. Nigro D., Fortes Z.B., Scivoletto R., Barbeiro H.V., Carvalho M.H.C. Sex-related differences in the response of spontaneously hypertensive rats to angiotensin-converting enzyme inhibitor. Endothelium. 5:1997;63-71.
24. Panza J.A., Quyyumi A.A., Brush J.E., Epstein S.E. Abnormal endothelium-dependent relaxation in patients with essential hypertension. N Engl J Med. 323:1990;22-27.
25. Rizzoni D., Castellano M., Porteri E., Bettoni G., Muiesan M.L., Cinelli A., Zulli R., Rosei E.A. Prolonged effects of short-term fosinopril on blood pressure and vascular morphology and function on rats. Am J Hypertens. 10:1997;1034-1043.
26. Rizzoni D., Porteri E., Castellano M., Bettoni G., Muiesan M.L., Tiberio G., Giuliani S.M., Rossi G., Bernini G., Agabiti-Rosei E. Endothelial dysfunction in hypertension is independent from the etiology and from vascular structure. Hypertension. 31(Part 2):1998;335-341.
27. Rubanyi G.M., Kauser K., Graser T. Effect of cilazapril and indomethacin on endothelial dysfunction in the aorta of spontaneously hypertensive rats. J Cardiovasc Pharmac. 2(suppl. 5):1993;523-530.
28. Schiffrin E.L., Deng L.Y. Comparison of effects of angiotensin- converting enzyme inhibition and β blockade for 2 years on function of arteries from hypertensive patients. Hypertension. 25(Part 2):1995;699-703.
29. Schiffrin E.L., Deng L.Y. Structure and function of resistance arteries of hypertensive patients treated with a β-blocker or a calcium channel antagonist. J Hypertens. 14:1996;1247-1255.
30. Shirasaki Y., Su C., Lee T.J.F., Kolm P., Kline W.H.J.R., Nickols G. Endothelial modulation of vascular relaxation to nitrovasodilators in aging and hypertension. J Pharmac Exp Ther. 239:1986;861-866.
31. 2+ efflux in arteries from deoxycorticosterone acetate hypertensive rats. Hypertension. 19:1992;734-738.
32. Taddei S., Virdis A., Mattei P., Salvetti A. Vasodilation to acetylcholine in primary and secondary forms of human hypertension. Hypertension. 21:1993;929-933.
33. Tshudi M.R., Criscione L., Novosel D., Pfeiffer K., Luscher T.F. Antihypertensive therapy augments endothelium-dependent relaxations in coronary arteries of spontaneously hypertensive rats. Circulation. 89:1994;2212-2218.