B cell epitopes of gliadin

Clinical and Experimental Immunology

Volumn 121, Issue 2, 2000, Pages 248-254

  Osman, A A ^a   Gunnel T ^a   Dietl, A ^a   Uhlig, H H ^a   Amin, M ^a   Fleckenstein, B ^b   Richter, T ^a   Mothes, T ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Coeliac disease; Epitopes; Gliadin antibodies; Pepscan; Phage display

Indexed keywords

EPITOPE; GLIADIN; GLIADIN ANTIBODY;

ANTIGEN BINDING; ARTICLE; B LYMPHOCYTE; CELIAC DISEASE; CONTROLLED STUDY; DEAMINATION; DISEASE ASSOCIATION; EPITOPE MAPPING; HUMAN; IMMUNOREACTIVITY; PHAGE DISPLAY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; B-LYMPHOCYTES; CELIAC DISEASE; EPITOPES; GLIADIN; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; SEQUENCE ALIGNMENT;

EID: 0033846974     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01312.x     Document Type: Article

References (33)

1. The immunologic basis for celiac disease and related disorders
2. Coeliac disease
3. The pathogenesis of celiac disease
4. Coeliac disease
5. Identification of tissue transglutaminase as the autoantigen of coeliac disease
6. Role of tissue transglutaminase in gliadin binding to reticular extracellular matrix and relation to coeliac disease autoantibodies
7. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
8. Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity
9. Identification of a gliadin T-cell epitope in coeliac disease: General importance of gliadin deamidation for intestinal T-cell recognition
10. Increased HLA-DQ2-affinity of a synthetic gliadin peptide by acidinduced deamidation of glutamine residues
11. Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin
12. HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope
13. T cells recognize a peptide derived from alpha-gliadin presented by the celiac disease-associated HLA-DQ (alpha 1*0501, beta 1*0201) heterodimer
14. Activation of celiac disease immune system by specific α-gliadin peptides
15. Anti-alpha-gliadin antibodies (AGA) in the serum of coeliac children and controls recognize an identical collection of linear epitopes of alpha-gliadin
16. Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease
17. Nucleic acid (cDNA) and amino acid sequences of alpha-type gliadins from wheat (Triticum aestivum)
18. Evolution and heterogeneity of the alpha-beta-type and gamma-type gliadin DNA sequences
19. The IgA subclass distribution of endomysium and gliadin antibodies in human sera is different
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Electroblotting of multiple gels: A simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose
22. Use of phage display technique for detection of epitopes recognized by polyclonal rabbit gliadin antibodies
23. Comparison of IgA-class reticulin and endomysium antibodies in coeliac disease and dermatitis herpetiformis
24. Epitope mapping by screening of phage display libraries of a monoclonal antibody directed against the receptor binding domain of human α2-23 macroglobulin
25. Nucleotide sequence of a gamma gliadin gene: Comparisons with other gamma gliadin sequences show the structure of gamma gliadin genes and the general primary structure of gamma gliadins
26. Spot synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support
27. Synthesis of peptide libraries on continuous cellulose membranes
28. The prolamin storage proteins of cereal seed: Structure and evolution
29. Conformational studies of peptides corresponding to the coeliac activating regions of wheat α-gliadin
30. Studies on the significance of the R1 anti-reticulin antibody associated with glucen sensitivity
31. Reaction of human noncolagenous polypeptides with coeliac disease autoantibodies
32. Anti-tissue transglutaminase, anti-endomysium and anti-R1-reticulin autoantibodies - The antibody trinity of coeliac disease
33. Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases