Differential coupling of α1-adrenoreceptor subtypes to phospholipase C and mitogen activated protein kinase in neonatal rat cardiac myocytes

European Journal of Pharmacology

Volumn 339, Issue 1, 1997, Pages 77-86

  Wenham, Dean ^a   Rahmatullah, Rownak J ^a   Rahmatullah, Mohammed ^a   Hansen, Carl A ^a   Robishaw, Janet D ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

1 Adrenoreceptor subtype; Cardiac myocyte, rat,neonatal; Mitogen activated protein kinase; Phosphatidylinositol hydrolysis

Indexed keywords

8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN BASIC PROTEIN; PHENYLEPHRINE; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; RECEPTOR SUBTYPE; ALPHA 1 ADRENERGIC RECEPTOR; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL CELL; ARTICLE; BINDING COMPETITION; BINDING SITE; CONTROLLED STUDY; HEART MUSCLE CELL; HYDROLYSIS; NEWBORN; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; HEART MUSCLE; METABOLISM; RADIOASSAY; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; BINDING, COMPETITIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; HYDROLYSIS; MYOCARDIUM; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 0031578458     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01359-9     Document Type: Article

References (52)

1. Berridge M.J., Dawson R.M., Downes C.P., Heslop J.P., Irvine R.F. Changes in the level of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides. Biochem. J. 212:1983;473-482.
2. Bogoyevitch M.A., Glennon P.E., Andersson M.B., Clerk A., Lazou A., Marshall C.J., Parker P.J., Sugden P.H. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. J. Biol. Chem. 269:1994;1110-1119.
3. Bogoyevitch M.A., Clerk A., Sugden P.H. Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes. Biochem. J. 309:1995;437-443.
4. 50) of an enzymatic reaction. Biochem. Pharmacol. 22:1973;3099-3108.
5. Clerk A., Bogoyevitch M.A., Andersson M.B., Sugden P.H. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rats. J. Biol. Chem. 269:1994;32848-32857.
6. 1-adrenergic receptor. Proc. Natl. Acad. Sci. USA. 85:1988;7159-7163.
7. D'Angelo D.D., Sakata Y., Lorenz J.N., Boivin G.P., Walsh R.A., Liggett S.B., Dorn II G.W. Transgenic Gαq overexpression induces cardiac contractile failure in mice. Proc. Natl. Acad. Sci. USA. 94:1997;8121-8126.
8. Dostal D.E., Rothblum K.N., Baker K.M. An improved method for the absolute quantification of mRNA using multiplex polymerase chain reaction: Determination of renin and angiotensinogen mRNA levels in various tissues. Anal. Biochem. 223:1994;239-250.
9. ras upon T-cell activation. Nature. 346:1990;719-723.
10. 1c-subtype. Mol. Pharmacol. 45:1994;703-708.
11. Gilman A. Nobel Lecture: G proteins and regulation of adenylyl cyclase. Biosci. Rep. 15:1995;65-97.
12. Goetz A.S., Lutz M.W., Rimele T.J., Saussy D.L. Characterization of alpha-1 adrenoreceptor subtypes in human and canine prostate membranes. J. Pharmacol. Exp. Ther. 271:1994;1228-1233.
13. 1-adrenoceptors. Eur. J. Pharmacol. 272:1995;R5-R6.
14. 1-adrenoceptor recognition sites by urapidil derivatives and other selective antagonists. Br. J. Pharmacol. 97:1989;691-700.
15. 2+ signaling in quiescent neonatal cardiac myoctes. Biochim. Biophys. Acta. 1224:1994;517-526.
16. Hansen C.A., Schroering A.G., Robishaw J.D. Subunit expression of signal transducing G proteins in cardiac tissue: Implications for phospholipase C-β regulation. J. Mol. Cell Cardiol. 27:1995;471-484.
17. Harrington E.O., Ware J.A. Diversity of the protein kinase C gene family. T. Cardiovasc. Med. 5:1995;193-199.
18. Hieble J.P., Bylund D.B., Clarke D.E., Eikenburg D.C., Langer S.Z., Lefkowitz R.J., Minneman K.P., Ruffolo R.R. Pharmacol. Rev. 47:1995;267270.
19. Kameshita I., Fujisawa H. A sensitive method for the detection of calmodulin-dependent protein kinase II activity in sodium dodecyl sulfate-polyacrylamide gel. Anal. Biochem. 183:1989;139-143.
20. 1A-adrenergic receptor subtype mediates biochemical, molecular and morphological features of cultured myocardial cell hypertrophy. J. Biol. Chem. 268:1993;15374-15380.
21. ras. Proc. Natl. Acad. Sci. USA. 91:1994;12706-12710.
22. Kolch W., Heidecker G., Kochs G., Hummel R., Vahidi H., Mischak H., Finkenzeller G., Marme D., Rapp U.R. Protein kinase Cα activates RAF-1 by direct phosphorylation. Nature. 364:1993;249-252.
23. 1A-subtype. Mol. Pharmacol. 46:1994;414-422.
24. Lazareno S., Birdsall N.J.N. Estimation of antagonist Kb from inhibition curves in functional experiments: Alternatives to the Cheng-Prusoff equation. Trends Pharmacol. Sci. 14:1993;237-239.
25. 1-adrenergic agonists in adult rat hearts. Am. J. Physiol. 267:1994;H970-H978.
26. Leff P., Dougall I.G. Further concerns over Cheng-Prusoff analysis. Trends Pharmacol. Sci. 14:1993;110-112.
27. 1A-adrenergic receptor. J. Biol. Chem. 266:1991;6365-6369.
28. 1A-subtype in rat submaxillary gland. Br. J. Pharmacol. 98:1989;883-889.
29. 1-adrenoceptor subtypes. Naunyn-Schmiedeberg's Arch. Pharmacol. 350:1994;136-142.
30. 1-adrenoceptor subtypes in rat heart. Br. J. Pharmacol. 111:1994;533-538.
31. 1B-adrenergic receptor in transgenic mice induced cardiac hypertrophy. Proc. Natl. Acad. Sci. USA. 91:1994;10109-10113.
32. 1-adrenergic receptor subtypes. Mol. Pharmacol. 46:1994;929-936.
33. Morgan H.E., Baker K.M. Cardiac hypertrophy. Mechanical, neural, and endocrine dependence. Circulation. 83:1991;13-25.
34. Nakafuku M., Satoh T., Kaziro Y. Differentiation factors, including nerve growth factor, fibroblast growth factor and interleukin-6, induce an accumulation of an active Ras. GTP complex in rat pheochromocytoma PC12 cells. J. Biol. Chem. 267:1992;19448-19454.
35. Neer E.J. Heterotrimeric G-proteins: Organizers of transmembrane signals. Cell. 80:1995;249-257.
36. 1D-adrenergic receptor cDNA. Mol. Pharmacol. 40:1991;876-883.
37. 1D-adrenergic receptors to multiple signaling pathways is both G protein and cell type specific. Mol. Pharmacol. 44:1993;784-795.
38. 1-adrenoceptors in vascular smooth muscle. Mol. Pharmacol. 46:1994;30-40.
39. 1C-. J. Biol. Chem. 271:1996;5839-5843.
40. 1D-AR subtype. Can. J. Physiol. Pharmacol. 72 (Suppl. 1):1994;13.1.8.
41. Schaffner W., Weissmann C. A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal. Biochem. 56:1973;502-514.
42. 1-adrenergic receptor subtype. J. Biol. Chem. 265:1990;8183-8189.
43. Schwinn D.A., Page S.O., Middleton J.P., Lorenz W., Ligget S.B., Yamamoto K., Lepetina E.G., Caron M.G., Lefkowitz R.J., Cotecchia S. The α1c-adrenergic receptor:Characterization of signal transduction pathways and mammalian tissue heterogeneity. Mol. Pharm. 40:1991;619-626.
44. Schwinn D.A., Johnston G.I., Page S.O., Mosley M.J., Wilson K.H., Worman N.P., Campbell S., Fidock M.D., Furness L.M., Parry-Smith D.J., Peter B., Bailey D.S. Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: Sequence corrections and direct comparison with other species homologues. J. Pharm. Exp. Therap. 272:1995;134-142.
45. Smrcka A.V., Sternweis P.C. Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits. J. Biol. Chem. 268:1993;9667-9674.
46. 1C-adrenergic receptor from cardiac myocytes. Circ. Res. 75:1994;796-802.
47. Sugden P.H., Bogoyevitch M.A. Intracellular signaling through protein kinases in the heart. Cardiovasc. Res. 30:1995;478-492.
48. 1-adrenergic receptor subtypes. Mol. Pharmacol. 37:1990;526-534.
49. 1-adrenoceptors: An overview. Pharmacol. Rev. 45:1993;147-175.
50. Thorburn J., McMahon M., Thorburn A. Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy. J. Biol. Chem. 269:1994;30580-30586.
51. van Biesen T., Hawes B.E., Luttrell D.K., Krueger K.M., Touhara K., Porfiri E., Sakaue M., Luttrell L.M., Lefkowitz R.J. Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signaling pathway. Nature. 376:1995;781-784.
52. Voigt M.M., Kispert J., Chin H. Sequence of a rat brain cDNA encoding an alpha-1B adrenergic receptor. Nucleic Acids Res. 18:1990;1053.