Improvement of pharmacokinetic, immunological and stability properties of asparaginase by conjugation to linear and branched monomethoxy poly(ethylene glycol)

Journal of Controlled Release

Volumn 40, Issue 3, 1996, Pages 199-209

  Veronese, Francesco M ^a   Monfardini, Cristina ^a   Caliceti, Paolo ^a   Schiavon, Oddone ^a   Scrawen, Michael D ^b   Beer, David ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

Asparaginase; Cancer therapy; Enzyme modification; Monomethoxy poly(ethylene glycol); mPEG

Indexed keywords

ASPARAGINASE; MACROGOL DERIVATIVE; POLYCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; DRUG ANTIGENICITY; DRUG CONJUGATION; DRUG DEGRADATION; ENZYME ACTIVITY; ENZYME MODIFICATION; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029888326     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00185-9     Document Type: Article

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