Detection of aneuploidy in chromosomes X, Y, 13, 18 and 21 by QF-PCR in 662 selected pregnancies at risk

Molecular Human Reproduction

Volumn 6, Issue 9, 2000, Pages 855-860

  Schmidt, Winfried ^a   Jenderny, Jutta ^a   Hecher, Kurt ^b   Hackelöer, B Joachim ^b   Kerber, Susanne ^a   Kochhan, Lothar ^a   Held, Karsten R ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b ASKLEPIOS HOSPITAL BARMBEK   (Germany)

Author keywords

Amniocyte; Prenatal diagnosis; Quantitative fluorescent polymerase chain reaction (qf pcr); Sex chromosome aberrations; Trisomy 13, 18 and 21

Indexed keywords

AMELOGENIN;

ADULT; AMNION FLUID; ANEUPLOIDY; ARTICLE; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME ABERRATION; FEMALE; HIGH RISK PREGNANCY; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; ROBERTSONIAN CHROMOSOME TRANSLOCATION; TANDEM REPEAT; X CHROMOSOME; Y CHROMOSOME;

EID: 0033841101     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/6.9.855     Document Type: Article

References (16)

1. Prenatal detection of chromosome aneuploidies by fluorescence in situ hybridization: Experience with 2000 uncultured amniotic fluid samples in a prospective preclinical trial
2. Rapid detection of chromosome X and Y aneuploidies by quantitative fluorescent PCR
3. A prospective comparative study on fluorescence in situ hybridisation (FISH) of uncultured amniocytes and standard karyotype analysis
4. Rapid prenatal diagnosis of aneuploidies in uncultured amniocytes by fluorescence in situ hybridisation (FISH)-evaluation of >3000 cases
5. Rapid determination of trisomy 18 parental origin using fluorescent PCR and small tandem repeat markers: Case reports
6. Prenatal detection of aneuploidy by directly labeled multicolored probes and interphase fluorescence in situ hybridization
7. Rapid detection of chromosome aneuploidies in uncultured amniocytes by using fluorescence in situ hybridization (FISH)
8. Defining the efficiency of fluorescence in situ hybridization on uncultured amniocytes on a retrospective cohort of 27407 prenatal diagnoses
9. Diagnosis of Down syndrome and other aneuploidies using quantitative polymerase chain reaction and small tandem repeat polymorphisms
10. PCR detection of structurally abnormal Y chromosomes
11. Rapid detection of trisomies 21 and 18 and sexing by quantitative fluorescent multiplex PCR
12. Rapid detection of chromosome aneuploidies by quantitative fluorescence PCR: First application on 247 chorionic villus samples
13. Effectiveness of prenatal chroniosomal analysis using multicolor fluorescent in situ hybridisation
14. Prenatal detection of trisomy 21 and 18 from amniotic fluid by quantitative fluorescent polymerase reaction
15. Rapid and simple prenatal DNA diagnosis of Down's syndrome
16. Rapid prenatal diagnosis of chromosomal aneuploidies by fluorescence in situ hybridization: Clinical experience with 4,500 specimens