Effectiveness of prenatal chromosomal analysis using multicolour fluorescent in situ hybridisation

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 107, Issue 2, 2000, Pages 262-266

  Thilaganathan, Baskaran ^a   Sairam, Shanthi ^a   Ballard, Terence ^b   Peterson, Caroline ^b   Meredith, Rodney ^b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b TDL Genetics   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SATELLITE DNA;

AMNION FLUID; ANEUPLOIDY; ARTICLE; CENTROMERE; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CLINICAL TRIAL; CONGENITAL DISORDER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEVICE; DIAGNOSTIC ACCURACY; DNA PROBE; FEMALE; FETUS; FETUS ECHOGRAPHY; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC SCREENING; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; PHENOTYPE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; TIME; TRISOMY; X CHROMOSOME; Y CHROMOSOME;

CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; COLOR; FEMALE; GENETIC SCREENING; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; PREGNANCY; PRENATAL DIAGNOSIS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY;

EID: 0033983677     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2000.tb11698.x     Document Type: Article

References (7)

1. Klinger K, Landes G, Shook D et al aneuploidies in uncultured amniocytes by using fluorescence in-situ hybridization (FISH). aneuploidies in uncultured amniocytes by using fluorescence in-situ hybridization (FISH) 1992; 51: 55–65.
2. Ward BE, Gersen S, Carelli MP, McGuire NM, Dackowski WR, Klinger KW. Rapid prenatal diagnosis of chromosomal aneupioidies by fluorescence in situ hybridization: clinical experience with 4500 specimens. Am J Hum Genet 1993; 52: 854–865.
3. D’Alton ME, Malone FD, Chelmow D, Ward BE, Bianchi DW. Defining the role of fluorescence in situ hybridization on uncultured amniocytes for prenatal diagnosis. Am J Obstet Gynecol 1997; 176: 769–776.
4. Bryndorf T, Christensen B, Vad M, Parner J, Brocks V, Philip J. Prenatal detection of chromosome aneuploidies by fluorescence in situ hybridization: experience with 2000 uncultured amniotic fluid sam.
5. Divane A, Carter NP, Spathas DH, Ferguson-Smith MA. Rapid Prenatal diagnosis of aneuploidy from uncultured amniotic fluid cells using five-colour fluorescence in-situ hybridization. Prenat Diagn 1994; 14: 1061–1069.
6. Jalal SM, Law ME, Carlson RO, Dewald GW. Prenatal detection of aneuploidy by directly labelled multicoloured probes and interphase fluorescence in situ hybridization. Mayo Clin Proc 1998; 73: 132–137.
7. Whiteman DAH, Klinger K. Efficiency of rapid in situ hybridization for prenatal diagnosis of chromosomal abnormalities causing birth defects [abstract]. Am J Hum Genet 1991; 49: 234.