Antisense inhibition of cyclin D1 in human head and neck squamous cell carcinoma

Archives of Otolaryngology - Head and Neck Surgery

Volumn 126, Issue 8, 2000, Pages 957-961

  Nakashima, Torahiko ^a   Clayman, Gary L ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; COMPLEMENTARY DNA; CYCLIN D1;

ANIMAL MODEL; ARTICLE; CELL CYCLE; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; FLOW CYTOMETRY; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PHENOTYPE; SQUAMOUS CELL CARCINOMA;

EID: 0033840219     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.126.8.957     Document Type: Article

References (26)

1. G1 events and regulation of cell proliferation
2. Mammalian G1 cyclins
3. G1 phase progression: Cycling on cue
4. Control of the G1/S transition
5. DP and E2F proteins: Components of a heterodimeric transcription factor implicated in cell cycle control
6. Cyclins and oncogenesis
7. PRAD-1 (CCND1)/cyclin D1 oncogene amplification in primary head and neck squamous cell carcinoma
8. Heterogeneity of the proliferative fraction and cyclin D1/CCND1 gene amplification in head and neck squamous cell carcinoma
9. Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression
10. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
11. Effect of cyclin D1 overexpression on drug sensitivity in a human fibrosarcoma cell line
12. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
13. Mutations and altered expression of p16lNK4 in human cancer
14. Methylation, a major mechanism of p16/CDKN2 gene inactivation in head and neck squamous carcinoma
15. Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck
16. Cyclin D1 overexpression in primary hypopharyngeal carcinomas
17. Markers for assessment of nodal metastasis in laryngeal carcinoma
18. Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus
19. A transgenic mouse model with cyclin D1 overexpression results in cell cycle, epidermal growth factor receptor, and p53 abnormalities
20. Dysregulated cyclin D1 expression early in head and neck tumorigenesis
21. Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells
22. Antisense to cyclin D1 inhibits growth and reverses the transformed phenotype of human esophageal cancer cells
23. Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum
24. Inhibition of cell proliferation in head and neck squamous cell carcinoma cell lines with antisense cyclin D1
25. Cyclin D1 is a nuclear protein required for cell cycle progression in G1
26. Inhibition of cyclin D1 expression in human pancreatic cancer cells is associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes