Evidence of lymphocyte alveolitis by bronchoalveolar lavage in thalassemic patients with pulmonary dysfunction

Acta Haematologica

Volumn 103, Issue 2, 2000, Pages 90-95

  Filosa, Aldo ^a,b   Esposito, V ^a   Meoli, I ^a   Baron, I ^a   Romano, L ^a  

^a CARDARELLI HOSPITAL   (Italy)

^b NONE   (Italy)

Author keywords

Bronchoalveolar lavage; Iron overload; Lung dysfunction; Lymphocyte alveolitis; Thalassemia

Indexed keywords

CARBON MONOXIDE; CD4 ANTIGEN; CD8 ANTIGEN; DEFEROXAMINE; HEMOGLOBIN; CARBOXYHEMOGLOBIN; IRON;

ADOLESCENT; ADULT; ARTICLE; BONE AGE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CYTOLOGY; FEMALE; HUMAN; HUMAN CELL; LUNG ALVEOLITIS; LUNG DIFFUSION CAPACITY; LUNG FUNCTION TEST; LUNG LAVAGE; LYMPHOCYTE; MACROPHAGE; MALE; MICROBIOLOGY; PRIORITY JOURNAL; SCHOOL CHILD; SPIROMETRY; THALASSEMIA; CHILD; CYTODIAGNOSIS; INTERSTITIAL LUNG DISEASE; IRON OVERLOAD; LEUKOCYTE COUNT; MICROBIOLOGICAL EXAMINATION;

EID: 0033839516     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000041026     Document Type: Article

References (26)

1. Hoyt RW, Scarpa N, Wilmott RW, Cohen A, Schwartz E: Pulmonary function abnormalities in homozygous β-thalassemia. J Pediatr 1986; 109:452-455.
2. Keens TG, O'Neal MH, Ortega JA, Hyman CB, Platzker CG: Pulmonary function abnormalities in thalassemia patients on a hypertransfusion program. Pediatrics 1980;65: 1013-1017.
3. Cooper DM, Mansell AL, Weiner MA, Berdon WE, Chetty-Baktaviziam A, Reid L, Mellins RB: Low lung capacity and hypoxemia in children with thalassemia major. Am Rev Respir Dis 1980;21:639-646.
4. Factor JM, Pottipati SR, Rappaport I, Rosner IK, Lesser ML, Giardina PJ: Pulmonary function abnormalities in thalassemia major and the role of iron overload. Am J Respir Crit Care Med 1994;149(6):1570-1574.
5. Fung KP, Chow OKW, So SY, Yuen PMB: Pulmonary function in thalassemia major. J Pediatr 1987;111:534-537.
6. Luyt DK, Richards GA, Roode H, Dowdeswell RJ, van Rensburg AJ, Reinach SG: Thalassemia: Lung function with reference to iron studies and reactive oxidant status. Pediatr Hematol Oncol 1993;10:13-23.
7. Tai DYH, Wang YT, Lou J, Mak KH, Cheng HK: Lung in thalassemia major patients receiving regular transfusion. Eur Respir J 1996;9: 1389-1394.
8. Brittenham GM, Griffith PM, Nienhuis AW, McLaren CE, Young NS, Tucker EE, Allen CE, Farrell DE, Harris JW: Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. N Engl J Med 1994;331(9):567-573.
9. Freedman MH, Grisaru D, Olivieri NF, McLusky I, Thorner PS: Pulmonary syndrome in patients with thalassemia major receiving intravenous desferoxamine infusions. Am J Dis Child 1990;144:565-569.
10. Lerner N, Blei F, Bierman F, Johnson L, Piomelli S: Chelation therapy and cardiac status in older patients with thalassemia major. Am J Pediatr Hematol Oncol 1990;12:56-60.
11. Low LCK: Growth, puberty and endocrine function in beta-thalassemia major. J Pediatr Endocrinol Metab 1997;10:175-184.
12. McIntosh N: Endocrinopathy in thalasscmia major. Arch Dis Child 1976;51:195-201.
13. Greulich WW, Pyle S: Radiographic Atlas of the Skeletal Development of Hand and Wrist, ed 2. Stanford, Stanford University Press, 1959.
14. Mansell A, Bryan C, Levison H: Airway closure in children. J Appl Physiol 1972;33:711.
15. Ogilvie CM, Forster RE, Blakemore WS, Morton JW: A standardised breath holding technique for the clinical measurement of the diffusing capacity of the lung lor carbon monoxide. J Clin Invest 1957;37:1-17.
16. Cotes JE, Dahhs JM, Elwood PC, Hall AM, McDonald A, Saunders MJ: Iron deficiency anemia: Its effect on transfer factor for the lung (diffusing capacity) and the ventilation and cardiac frequency during sub-maximal exercise. Gin Sci 1972;42:325-335.
17. Cotes JE: Lung function: Assessment and Applications in Medicine. Oxford, Blackwell Scientific, 1975.
18. American Thoracic Society: Lung function testing: Selection of reference values and interpretative strategies. Am Rev Respir Dis 1991; 144:1202-1218.
19. Ratjen F, Bredendiek M, Zheng L, Brendel M, Costabel U: Lymphocyte subset s in bronchoalveolar lavage fluid of children without bronchopulmonary disease. Am J Respir Crit Care Med 1995;152(1):174-178.
20. Riedler J, Grigg J, Stone C, Tauro G, Robertson CF: Bronchoalveolar lavage cellularity in healthy children. Am J Respir Crit Care Med 1995;152(1):163-168.
21. Grisaru D, Rachmilewitz EA, Mosseri M, Gatsman M, Lafair JS, Okon E, Goldfarb A, Hasin Y: Cardiopulmonary assessment in beta-thalassemia. Chest 1990;98:1138-1142.
22. Cappel DF, Hutchinson HE, Jowett M: Transfusional siderosis. The effects of excessive iron deposits on the tissue. J Pathol Bacteriol 1957; 74:245-247.
23. Landing BH, Nadorra R, Hyman CB, Ortega JA: Pulmonary lesions of thalassemia major. Perspect Pediatr Pathol 1987;11:82-86.
24. Fan LL, Lung MC, Wagoner JS: The diagnostic value of bronchoalveolar lavage in immunocompetent children with chronic diffuse pulmonary infiltrates. Pediatr Pulmonol 1997;23: 8-13.
25. Tenenbien M, Kowalski S, Sienko A, Bowden DH, Adamson IY: Pulmonary toxic effects of continuous desferoxamine administration in acute iron poisoning. Lancet 1992;339:699-701.
26. Helson L, Helson C, Braverman S, Deb G, Donfrancesco A: Desferrioxamine in acute iron poisoning. Lancet 1992;339:1601-1605.