Combination of granulocyte colony-stimulating factor and low-dose cytosine arabinoside further enhances myeloid differentiation in leukemia cells in vitro

Leukemia and Lymphoma

Volumn 39, Issue 1-2, 2000, Pages 173-184

  Katagiri, T ^a   Miyazawa, K ^a   Nishimaki, J ^a   Yaguchi, M ^a   Kawanishi, Y ^a   Ohyashiki, K ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Acute myeloid leukemia; Cytosine arabinoside; Differentiation; G CSF; Myelodysplastic syndromes

Indexed keywords

CYTARABINE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL ISOLATION; CELL KILLING; CELL STIMULATION; CELL SUSPENSION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MALE; MALIGNANT TRANSFORMATION; MOUSE; MYELODYSPLASTIC SYNDROME; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL;

EID: 0033837782     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009053552     Document Type: Article

References (37)

1. Differentiation therapy of leukemia: Achievements, limitations and future prospects
2. All-trans retinoic acid and hematopoietic growth factors regulating the growth and differentiation of blast progenitors in acute promyelocytic leukemia
3. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
4. Acute promyelocytic leukemia: Biology and treatment
5. Low-dose cytarabine versus intensive chemotherapy in the treatment of acute nonlymphocytic leukemia in the elderly
6. Review of clinical and haematological response to low-dose cytosine arabinoside in acute myeloid leukemia
7. Concurrent use of granulocyte colony-stimulating factor with low-dose cytosine arabinoside and aclarubicin for previously treated acute myelogenous leukemia: A pilot study
8. Priming with G-CSF effectively enhances low-dose Ara-C-induced in vivo apoptosis in myeloid leukemia cells
9. Granulocyte-macrophage colony-stimulating factor enhances the cytotoxic effects of cytosine arabinoside in acute myeloblastic leukemia and in the myeloid blast crisis phase of chronic myeloid leukemia
10. Growth factors influence the sensitivity of leukemic stem cells to cytosine arabinoside in culture
11. Megakaryocytic maturation is regulated by maintaining a balance against cytokine induced-cell proliferation: Steel factor retards thrombopoietin-induced megakaryocytic differentiation while synergistically stimulating mitogenesis
12. Recombinant human granulocyte colony-stimulating factor: Effects on normal and leukemic myeloid cells
13. Proposals for the classification of acute leukemias
14. Proposals for the classification of the myelodysplastic syndromes
15. Autoinduction of differentiation in WEHI-3B leukemia cells
16. Effects of recombinant IL-3, GM-CSF, and G-CSF on proliferation of leukemic clonogenic cells in short-term and long-term cultures
17. Growth response of human myeloid leukemia cells to colony-stimulationg factors
18. Growth regulations of human acute myeloid leukemia: Effect of five recombinant hematopoietic factors in a serum-free culture system
19. Interleukin-3, GM-CSF, and G-CSF receptor expression on cell lines and primary leukemia cells: Receptor heterogeneity and relationship to growth factor responsiveness
20. Human granulocyte colony-stimulating factor receptors in acute myelogenous leukemia
21. Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation
22. Functional differentiation signals mediated by distinct regions of the cytoplasmic domain of the granulocyte colony-stimulation factor receptor
23. Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor
24. Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for STAT3 activation
25. Distinct signal transduction through the tyrosine-containing domains of the granulocyte colony-stimulating factor receptor
26. Stat3 and G-CSF-induced myeloid differentiation
27. The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitors
28. Murine puluripotent hematopoietic progenitors constitutively expressing a normal erythropoietin receptor proliferate in response to erythropoietin without preferential erythroid cell differentiation
29. Multi-colony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor α subunit constitutively
30. A human GM-CSF receptor expressed in transgenic mice stimulates proliferation and differentiation of hemopoietic progenitors to all lineages in response to human GM-SCF
31. Human granulocyte colony-stimulating factor (G-CSF) stimulates the in vitro and in vivo development but not commitment of primitive multipotential progenitors from transgenic mice expressing the human G-CSF receptor
32. Specific signals generated by the cytoplasmic domain of the granulocyte colony-stimulating factor (G-CSF) receptor are not required for G-CSF-dependent granulocytic differentiation
33. Apoptosis is a common histopathological finding in myelodysplasia. The correlate of ineffective hematopoiesis
34. Use of colony-stimulation factors in ther treatment of acute myeloid leukemia
35. Effect of 1-β-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function
36. Substrate-specific deoxycytidine kinase deficiency in 1-β-D-arabinofuranosyl-cytosine-resistant leukemia cells
37. Leukemic blasts differ from normal bone marrow mononuclear cells and CD34+ hemopoietic stem cells in their metabolism of cytosine arabinoside