Distinct signal transduction through the tyrosine-containing domains of the granulocyte colony-stimulating factor receptor

EMBO Journal

Volumn 14, Issue 21, 1995, Pages 5288-5296

  Yoshikawa, Akikazu ^a,b   Murakami, Hiroshi ^a   Nagata, Shigekazu ^a  

^a OSAKA BIOSCIENCE INSTITUTE   (Japan)

^b PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Colony stimulating factor; G CSF receptor; Neutrophilic differentiation; Site directed mutagenesis; Tyrosine phosphorylation

Indexed keywords

CELL PROTEIN; CYTOKINE RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR; INTERLEUKIN 3; MUTANT PROTEIN; MYELOPEROXIDASE; PHENYLALANINE; TYROSINE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ANIMALIA;

EID: 0028872063     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1995.tb00213.x     Document Type: Article

References (44)

1. Akira,S. et al. (1994) Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell, 77, 63-71.
2. Arai,K.-I., Lee,R., Miyajima,A., Miyatake,S., Arai,N. and Yokota,Y. (1990) Cytokines: Coordinators of immune and inflammatory responses. Annu. Rev. Biochem., 59, 783-836.
3. Bazan,J.F. (1990) Haemopoietic receptors and helical cytokines. Immunol. Today, 11, 350-354.
4. Chomczynski,P. and Sacchi,N. (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
5. Copper,J.A., Esch,F.S., Taylor,S.S. and Hunter,T. (1984) Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro. J. Biol. Chem., 259, 7835-7841.
6. Corey,S.J., Burkhardt,A.L., Bolen,J.B., Geahlen,R.L., Tkatch,L.S. and Tweardy,D.J. (1994) Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases. Proc. Natl Acad. Sci. USA, 91, 4683-4687.
7. Darnell,J.E.,Jr, Kerr,I.M. and Stark,G.R. (1994) Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science, 264, 1415-1421.
8. Demetri,G.D. and Griffin,J.D. (1991) Granulocyte colony-stimulating factor and its receptor. Blood, 78, 2791-2808.
9. Dong,F., van Buitenen,C., Pouwels,K., Hoefsloot,L.H., Löwenberg,B. and Touw,I.P. (1993) Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturation. Mol. Cell. Biol., 13, 7774-7781.
10. Fukunaga,R., Ishizaka-Ikeda,E., Seto,Y. and Nagata,S. (1990a) Expression cloning of a receptor for murine granulocyte colony-stimulating factor. Cell, 61, 341-350.
11. Fukunaga,R., Seto,Y., Mizushima,S. and Nagata,S. (1990b) Three different mRNAs encoding human granulocyte colony-stimulating factor receptor. Proc. Natl Acad. Sci. USA, 87, 8702-8706.
12. Fukunaga,R., Ishizaka-Ikeda,E. and Nagata,S. (1990c) Purification and characterization of the receptor for murine granulocyte colony-stimulating factor. J. Biol. Chem., 265, 14008-14015.
13. Fukunaga,R., Ishizaka-Ikeda,E., Pan,C.-X., Seto,Y. and Nagata,S. (1991) Functional domains of the granulocyte colony-stimulating factor receptor. EMBO J., 10, 2855-2865.
14. Fukunaga,R., Ishizaka-Ikeda,E. and Nagata,S. (1993) Growth and differentiation signals mediated by two distinct regions in the cytoplasmic domain of G-CSF receptor. Cell, 14, 1079-1087.
15. Heldin,C.-H. (1995) Dimerization of cell surface receptors in signal transaction. Cell, 80, 213-223.
16. Hilton,D.J. (1992) LIF: lots of interesting functions. Trends Biochem. Sci., 17, 72-76.
17. Ihle,J.N. and Kerr,I.M. (1995) Jaks and Stats in signaling by the cytokine receptor superfamily. Trends Genet., 11, 69-74.
18. Ihle,J.N., Witthuhn,B.A., Quelle,F.W., Yamamoto,K., Thierfelder,W.E., Kreider,B. and Silvennoinen,O. (1994) Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem. Sci, 19, 222-227.
19. Ishizaka-Ikeda,E., Fukunaga,R., Wood,W.I., Goeddel,D.V. and Nagata,S. (1993) Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptor. Proc. Natl. Acad. Sci. USA, 90, 123-127.
20. Kishimoto,T. (1989) The biology of interleukin-6. Blood, 74, 1-10.
21. Kishimoto,T., Taga,T. and Akira,S. (1994) Cytokine Signal Transduction. Cell, 76, 253-262.
22. Larsen,A. et al. (1990) Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains. J. Exp. Med., 172, 1559-1570.
23. Lee,K.H., Kinashi,T., Tohyama,K., Tashiro,K., Funato,N., Hama,K. and Honjo,T. (1991) Different stromal cell lines support lineage-selective differentiation of the multipotential bone marrow stem cell clone LyD9. J. Exp. Med., 173, 1257-1266.
24. Lieschke,G.J. et al. (1994) Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impared neutrophil mobilization. Blood, 84, 1737-1746.
25. Marshall,C.J. (1995) Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell, 80, 179-185.
26. Metcalf,D. (1989) The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature, 339, 27-30.
27. Metcalf,D. (1992) Hemopoietic regulators. Trends Biochem. Sci., 17, 286-289.
28. Muî,A.L.-F. and Miyajima,A. (1994) Cytokine receptors and signal transduction. Progr. Growth Factor Res., 5, 15-35.
29. Nagata,S. (1994). Granulocyte colony-stimulating factor. In Thomson, A.W. (ed.). The Cytokine Handbook. Academic Press, London, pp. 371-385
30. Nagata,S. and Fukunaga.R. (1991) Granulocyte colony-stimulating factor and its receptor. Progr. Growth Factor Res., 3, 131-141.
31. Nicholson,S.E., Oates,A.C., Harpur,A.G., Ziemiecki,A., Wilks,A.F. and Layton,J.E. (1994) Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation. Proc. Natl Acad. Sci. USA, 91, 2985-2988.
32. Pan,C.-X., Fukunaga,R., Yonehara,S. and Nagata,S. (1993) Unidirectional cross-phosphorylation between the G-CSF and IL-3 receptors. J. Biol. Chem., 268, 25818-25823.
33. Pawson,T. (1995) Protein modules and signalling networks. Nature, 373, 573-580.
34. Schlessinger,J. and Ullrich,A. (1992) Growth factor signaling by receptor tyrosine kinases. Neuron, 9, 383-391.
35. Seldin,D.C. and Leder,P. (1994) Mutational analysis of a critical signaling domain of the human interleukin 4 receptor. Proc. Natl Acad. Sci. USA, 91, 2140-2144.
36. Shimoda,K. et al. (1992) Granulocyte colony-stimulating factor receptors on human acute leukemia: biphenotypic leukemia cell possess granulocytes colony-stimulating factor receptors. Cancer Res., 52, 3052-3055.
37. Shimoda,K., Iwasaki,H., Okamura,S., Ohno,Y., Kubota,A., Arimura,F., Otsuka,T. and Niho,Y. (1994) G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils. Biochem. Biophys. Res. Commun., 203, 922-928.
38. Songyang,Z. et al. (1995) Catalytic specificity of protein-tyrosine kinases is critical for selecting signaling. Nature. 373, 536-539.
39. Stahl,N., Farruggella,T.J., Boulton,T.G., Zhong,Z., Darnell,J.E.,Jr and Yancopoulos,G.D. (1995) Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science, 267, 1349-1353.
40. Tian,S.-S., Lamb,P, Seidel,H.M., Stein,R.B. and Rosen,J. (1994) Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor. Blood, 84, 1760-1764.
41. Tsuchiya,M., Asano,S., Kaziro,Y. and Nagata,S. (1986) Isolation and characterization of the cDNA for murine granulocyte colony stimulating factor. Proc. Natl Acad. Sci. USA, 83, 7633-7637.
42. Uetsuki,T., Naito,A., Nagata,S. and Kaziro,Y. (1989) Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor 1α. J. Biol. Chem., 264, 5791-5798.
43. Venturelli,D., Shirsat,N., Gemperlein,I., Bittenbender,S., Hudson,S. and Rovera,G. (1989) Nucleotide sequence of cDNA for murine myeloperoxidase. Nucleic Acids Res., 17, 5852.
44. Ziegler,S.F., Bird,T.A., Morella,K.K., Mosley,B., Gearing,D.P. and Baumann,H. (1993) Distinct regions of the human granulocyte-colony-stimulating factor receptor cytoplasmic domain are required for proliferation and gene induction. Mol. Cell. Biol., 13, 2384-2390.