Assembly, secretion, and vacuolar delivery of a hybrid immunoglobulin in plants

Plant Physiology

Volumn 123, Issue 4, 2000, Pages 1483-1493

  Frigerio, L ^a   Vine, N D ^a   Pedrazzini, E ^a   Hein, M B ^a   Wang, F ^a   Ma, J K C ^a   Vitale, A ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL VACUOLE; ENDOPLASMIC RETICULUM; HYBRID IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; PROTEIN DOMAIN; PROTEIN STRUCTURE;

NICOTIANA TABACUM; TABACUM;

EID: 0033836692     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.123.4.1483     Document Type: Article

References (44)

1. Delivery of a secreted soluble protein to the vacuole via a membrane anchor
2. A carboxyl-terminal propeptide is necessary for proper sorting of barley lectin to vacuoles of tobacco
3. Stacks on tracks: The plant Golgi apparatus traffics on an actin/ER network
4. ER protein quality control and proteasome-mediated protein degradation
5. Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity
6. The maize γ-zein sequesters α-zein and stabilizes its accumulation in protein bodies of transgenic tobacco endosperm
7. Compartment-specific accumulation of recombinant immunoglobulins in plant cells: An essential tool for antibody production and immunomodulation of physiological functions and pathogen activity
8. Saturation of the endoplasmic reticulum retention machinery reveals anterograde bulk flow
9. Protein secretion in plant cells can occur via a default pathway
10. Targeting of proteins to the vacuole
11. Determination of the functional elements within the vacuolar targeting signal of barley lectin
12. Sorting of phaseolin to the vacuole is saturable and requires a short C-terminal peptide
13. Isolation of intracellular membranes by means of sodium carbonate treatment: Application to endoplasmic reticulum
14. Tonoplast and soluble vacuolar proteins are targeted by different mechanisms
15. The efficiency of cysteine-mediated intracellular retention determines the differential fate of secretory IgA and IgM in B and plasma cells
16. Production of antibodies in transgenic plants
17. Isolation of prolegumin from developing pea seeds: Its binding to endomembranes and assembly into prolegumin hexamers in the protein storage vacuole
18. A pathway for targeting soluble misfolded proteins to the yeast vacuole
19. The signal peptide of a vacuolar protein is necessary and sufficient for the efficient secretion of a cytosolic protein
20. Immunotherapeutic potential of antibodies produced in plants
21. Generation and assembly of secretory antibodies in plants
22. Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans
23. Assembly of monoclonal antibodies with IgG1 and IgA heavy chain domains in transgenic tobacco plants
24. Degradation of unassembled soluble Ig subunits by cytosolic proteasomes: Evidence that retrotranslocation and degradation are coupled events
25. Plant vacuoles
26. Different sensitivity to wortmannin of two vacuolar sorting signals indicates the presence of distinct sorting machineries in tobacco cells
27. Propeptide of a precursor to a plant vacuolar protein required for vacuolar targeting
28. Immunoglobulin A (IgA): Molecular and cellular interactions involved in IgA bio-synthesis and immune response
29. Sorting of proteins to vacuoles in plant cells
30. Protein quality control along the route to the plant vacuole
31. Binding of BiP to an assembly-defective protein in plant cells
32. 5 with a lengthened membrane anchor escapes from the endoplasmic reticulum and reaches the plasma membrane
33. Degradation of transport-competent destabilized phaseolin with a signal for retention in the endoplasmic reticulum occurs in the vacuole
34. The protein N-glycosylation in plants
35. Cellular localization of nodule-enhanced aspartate aminotransferase in Medicago sativa L
36. Different legumin protein domains act as vacuolar targeting signals
37. The specificity of vesicle trafficking: Coat proteins and SNAREs
38. Colocalization of barley lectin and sporamin in vacuoles of transgenic tobacco plants
39. Developmental regulation of IgM secretion: The role of the carboxy-terminal cysteine
40. A biotechnological approach to improving the nutritive value of alfalfa
41. Studies on the structural and conformational basis for the relative resistance of serum and secretory immunoglobulin A to proteolysis
42. The endoplasmic reticulum: Gateway of the secretory pathway
43. What do proteins need to reach different vacuoles?
44. Vicilin with carboxy-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants