Hypoxia reduces atrial natriuretic peptide clearance receptor gene expression in ANP knockout mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 279, Issue 3 23-3, 2000, Pages

  Sun, Ju Zhong ^a   Chen, Shi Juan ^a   Li, Guohong ^a   Chen, Yiu Fai ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Pulmonary hypertension

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; MESSENGER RNA;

ADAPTATION; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART RIGHT VENTRICLE HYPERTROPHY; HYPOXIA; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033834466     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.279.3.l511     Document Type: Article

References (35)

1. Clearance of human brain natriuretic peptide in rabbit; effect of the kidney, the natriuretic peptide clearance receptor, and peptidase activity
2. The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia
3. The biochemistry of atrial natriuretic peptides
4. The guanylyl cyclase-A receptor
5. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
6. Brain natriuretic peptide: Possible role in the modulation of hypoxic pulmonary hypertension
7. Basic FGF decreases clearance receptor of natriuretic peptide in feto-placental artery endothelium
8. Atrial natriuretic peptide clearance receptor agonist lowers pulmonary pressure in hypoxic rats
9. ANP in acute hypoxia-induced pulmonary hypertension in rats
10. ANP attenuates the development of pulmonary hypertension in rats adapted to chronic hypoxia
11. Atrial natriuretic peptide lowers pulmonary arterial pressure in hypoxia-adapted rats
12. Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension
13. Increased expression of PDGF A- and B-chain genes in rat lungs with hypoxic pulmonary hypertension
14. Cyclic GMP down-regulates atrial natriuretic peptide receptors on cultured vascular endothelial cells
15. Downregulation of C-receptor by natriuretic peptides via ANP-B receptor in vascular smooth muscle cells
16. Natriuretic peptide clearance receptor is transcriptionally down-regulated by β2-adrenergic stimulation in vascular smooth muscle cells
17. Downregulation of pulmonary atrial natriuretic peptide receptors in rats exposed to chronic hypoxia
18. Cardiopulmonary responses to chronic hypoxia in transgenic mice that over-express ANP
19. C-type natriuretic peptide expression and pulmonary vasodilation in hypoxia-adapted rats
20. Brain natriuretic peptide inhibits hypoxic pulmonary hypertension in rats
21. Genetic disruption of atrial natriuretic peptide causes pulmonary hypertension in normoxic and hypoxic mice
22. Atrial natriuretic peptide expression in rats with different pulmonary hypertensive responses to hypoxia
23. Selective activation of the B type natriuretic peptide receptor by C-type natriuretic peptide (CNP)
24. Effects of chronic hypoxia and altered hemodynamic on endothelial nitric oxide synthase expression in the adult rat lung
25. Molecular determinants of natriuretic peptide clearance receptor function
26. Regulation of ANP-C receptor gene expression in human pulmonary vascular smooth muscle cells
27. Selective downregulation of ANP-clearance-receptor gene expression in lung of rats adapted to hypoxia
28. Atrial natriuretic peptide in acute hypoxia-exposed healthy subjects and in hypoxaemic patients
29. The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system
30. Plasma brain natriuretic peptide levels increase in proportion to the extent of right ventricular dysfunction in pulmonary hypertension
31. Atrial and brain natriuretic peptides in cardiovascular diseases
32. Inhibition of hypoxic pulmonary vasoconstriction in isolated rat resistance arteries by atrial natriuretic peptide
33. Physiology of the clearance receptor
34. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice
35. Regulation of atrial natriuretic peptide receptors in vascular smooth muscle cells: Role of cGMP