Prion-dependent switching between respiratory competence and deficiency in the yeast nam9-1 mutant

Molecular and Cellular Biology

Volumn 20, Issue 19, 2000, Pages 7220-7229

  Chacinska, A ^a   Boguta, M ^a   Krzewska, J ^a   Rospert, S ^a  

^a MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME SUBUNIT; GENE DELETION; GENE MUTATION; GENE SWITCHING; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RESPIRATORY FAILURE; SACCHAROMYCES CEREVISIAE; TEMPERATURE DEPENDENCE; YEAST;

CYTOCHROME-C OXIDASE; CYTOSOL; DNA, FUNGAL; DNA, MITOCHONDRIAL; FUNGAL PROTEINS; GENE DELETION; GUANIDINE; HEAT-SHOCK PROTEINS; MITOCHONDRIA; OXYGEN CONSUMPTION; PHENOTYPE; PLANT PROTEINS; POINT MUTATION; PRIONS; RIBOSOMAL PROTEINS; SACCHAROMYCES CEREVISIAE; SUPPORT, NON-U.S. GOV'T; TRANSLATION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 0033834076     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.19.7220-7229.2000     Document Type: Article

References (83)

1. Two adjacent nuclear genes, ISF1 and NAM7/UPF1, cooperatively participate in mitochondrial functions in Saccharomyces cerevisiae
2. The single amino acid changes in the yeast mitochondrial S4 ribosomal protein cause temperature-sensitive defect in the accumulation of mitochondrial 15S rRNA
3. Expression of the yeast NAM9 gene coding for mitochondrial ribosomal protein
4. NAM9 nuclear suppressor of mitochondrial ochre mutations in Saccharomyces cerevisiae codes for a protein homologous to S4 ribosomal proteins from chloroplasts, bacteria, and eucaryotes
5. OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis
6. One-step transformation of yeast in stationary phase
7. Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor
8. Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae
9. +]
10. Evidence for a protein mutator in yeast: Role of the Hsp70-related chaperone Ssb in formation, stability, and toxicity of the [PSI] prion
11. MTO1 codes for a mitochondrial protein required for respiration in paromomycin resistant mutants of Saccharomyces cerevisiae
12. A mutant of Saccharomyces cerevisiae defective for nuclear fusion
13. The psi factor of yeast: A problem in inheritance
14. The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs
15. MSS1, a nuclear-encoded mitochondrial GTPase involved in the expression of COX1 subunit of cytochrome c oxidase
16. +] prion in Saccharomyces cerevisiae
17. Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae
18. Ribosome-bound EF-1 alpha-like protein of yeast Saccharomyces cerevisiae
19. The NAM9-1 suppressor mutation in a nuclear gene encoding ribosomal mitochondrial protein of Saccharomyces cerevisiae
20. Long range control circuits within mitochondria and between nucleus and mitochondria. I. Methodology and phenomenology of suppressors
21. Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanism
22. Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [PSI(+)] of Saccharomyces cerevisiae
23. Reduced dosage of genes encoding ribosomal protein S18 suppresses a mitochondrial initiation codon mutation in Saccharomyces cerevisiae
24. Translational control of endogenous and recoded nuclear genes in yeast mitochondria: Regulation and membrane targeting
25. Nascent polypeptide-associated complex stimulates protein import into yeast mitochondria
26. In vitro protein translocation across microsomal membranes of Saccharomyces cerevisiae
27. Isolation of highly purified mitochondria from Saccharomyces cerevisiae
28. Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae
29. Mitochondrial ribosomal proteins (MRPs) of yeast
30. Functional interactions between yeast mitochondrial ribosomes and mRNA 5' untranslated leaders
31. Mitochondrial assembly in yeast
32. Immunochemical identification of membrane proteins after sodium dodecyl sulfate-polyacrylamide gel electrophoresis
33. The cytoplasmic chaperone hsp104 is required for conformational repair of heat-denatured proteins in the yeast endoplasmic reticulum
34. Membrane translocation of mitochondrially coded Cox2p: Distinct requirements for export of N and C termini and dependence on the conserved protein Oxa1p
35. Recombinational analysis of OXI1 mutants and preliminary analysis of their translation products in S. cerevisiae
36. Structure and replication of yeast prions
37. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
38. Molecular and biochemical analysis of Saccharomyces cerevisiae cox1 mutants
39. The yeast [PSI+] prion: Making sense of nonsense
40. An essential yeast protein, encoded by duplicated genes TIF1 and TIF2 and homologous to the mammalian translation initiation factor eIF-4A, can suppress a mitochondrial missense mutation
41. Mad cows meet psi-chotic yeast: The expansion of the prion hypothesis
42. Heat-shock protein 104 expression is sufficient for thermotolerance in yeast
43. The role of Hsp104 in stress tolerance and [PSI+] propagation in Saccharomyces cerevisiae
44. Reversion analysis of [psi-] mutations in Saccharomyces cerevisiae
45. Misreading of the ribosomal suppressor SUP46 due to an altered 40 S subunit in yeast
46. Reduced but accurate translation from a mutant AUA initiation codon in the mitochondrial COX2 mRNA of Saccharomyces cerevisiae
47. Multiple genes, including a member of the AAA family, are essential for degradation of unassembled subunit 2 of cytochrome c oxidase in yeast mitochondria
48. Antagonistic interactions between yeast chaperones Hsp104 and Hsp70 in prion curing
49. Protein disaggregation mediated by heat-shock protein Hsp104
50. Support for the prion hypothesis for inheritance of a phenotypic trait in yeast
51. Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor
52. In vitro propagation of the prion-like state of yeast Sup35 protein
53. PET111, a Saccharomyces cerevisiae nuclear gene required for translation of the mitochondrial mRNA encoding cytochrome c oxidase subunit II
54. Protein translocation into mitochondria
55. Hsp104 is required for tolerance to many forms of stress
56. Accumulation of mitochondrially synthesized Saccharomyces cerevisiae Cox2p and Cox3p depends on targeting information in untranslated portions of their mRNAs
57. Molecular basis of a yeast prion species barrier
58. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
59. HSP100/Clp proteins: A common mechanism explains diverse functions
60. Interactions of the chaperone Hsp104 with yeast Sup35 and mammalian PrP
61. [PSI+]: An epigenetic modulator of translation termination efficiency
62. Mitochondrial membrane biogenesis: Identification of a precursor to yeast cytochrome c oxidase subunit II, an integral polypeptide
63. The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae
64. Preparation and use of antibodies against insoluble membrane proteins
65. Recessive suppression in yeast Saccharomyces cerevisiae is mediated by a ribosomal mutation
66. The SUP35 omnipotent suppressor gene is involved in the maintenance of the non-Mendelian determinant [psi+] in the yeast Saccharomyces cerevisiae
67. Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non-overlapping functional regions in the encoded protein
68. Ribosomal recessive suppressors cause a respiratory deficiency in yeast Saccharomyces cerevisiae
69. Sensitivity of sup35 and sup45 suppressor mutants in Saccharomyces cerevisiae to the anti-microtubule drug benomyl
70. Agents that cause a high frequency of genetic change from [psi+] to [psi-] in Saccharomyces cerevisiae
71. The yeast omnipotent suppressor SUP46 encodes a ribosomal protein which is a functional and structural homolog of the Escherichia coli S4 ram protein
72. Isolation and characterization of omnipotent suppressors in the yeast Saccharomyces cerevisiae
73. [URE3] as an altered URE2 protein: Evidence for a prion analog in Saccharomyces cerevisiae
74. [PSI] and [URE3] as yeast prions
75. Prions in Saccharomyces and Podospora spp.: Protein-based inheritance
76. Two nuclear mutations that block mitochondrial protein import in yeast
77. The yeast non-Mendelian factor [ETA+] is a variant of [PSI+], a prion-like form of release factor eRF3
78. Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3