Assessment of ret/PTC-I rearrangements in neoplastic thyroid tissue using taqman RT-PCR

Journal of Pathology

Volumn 192, Issue 1, 2000, Pages 32-36

  Sheils, Orla M ^a   O'Leary, John J ^b   Sweeney, Eamon C ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b Molecular Pathology Laboratory   (Ireland)

Author keywords

Paraffin embedded tissue; Ret PTC 1; RT PCR; TaqMan; Thyroid carcinoma; Thyroiditis

Indexed keywords

HISTONE H4; ONCOPROTEIN;

ANAPLASTIC CARCINOMA; ARTICLE; GENE ACTIVATION; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; INFLAMMATORY INFILTRATE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THYROID ADENOMA; THYROID CARCINOMA; THYROID FOLLICULAR CARCINOMA; THYROIDITIS;

CARCINOMA, PAPILLARY; ELECTROPHORESIS, AGAR GEL; GENE REARRANGEMENT; HUMANS; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; PROGNOSIS; PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYROID NEOPLASMS; THYROIDITIS, AUTOIMMUNE; TUMOR MARKERS, BIOLOGICAL;

EID: 0033832617     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH668>3.0.CO;2-F     Document Type: Article

References (26)

1. Papillary and follicular thyroid carcinoma
2. Clinicopathologic and immunohistochemical studies of papillary thyroid microcarcinoma presenting with cervical lymphadenopathy
3. EGF-receptors in human normal and pathological thyroid tissue
4. TSH receptor status of thyroid neoplasms TaqMan RT-PCR analysis of archival material
5. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
6. Involvement of RET oncogene in human tumours: Specificity of RET activation to thyroid tumours
7. Identification of tumour specific translocations in archival material
8. Cloning and characterization of H4 (D10S170), a gone involved in RET rearrangements in vivo
9. The physical map of the human RET proto-oncogene
10. Characterisation of the promoter region and oligomerisation domain of H4 (D10S170), a gene frequently rearranged with the ret proto-oncogene
11. Molecular and cytogenetic characterisation of a t(1;10;21) translocation in the human papillary thyroid cancer cell line TPC-1 expressing the ret/H4 chimeric transcript
12. The ret/PTC oncogene in papillary thyroid carcinoma
13. ret/PTC-1, -2, and -3 oncogene rearrangements in human thyroid carcinomas: Implications for metastatic potential?
14. High prevalence of RET rearrangement in thyroid tumours of children from Belarus after the Chernobyl reactor accident
15. RET/NTRK1 rearrangements in thyroid gland tumours of the papillary carcinoma family: Correlation with clinicopathological features
16. Sporadic ret-rearranged papillary carcinoma of the thyroid: A subset of slow growing, less aggressive thyroid neoplasms
17. RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes
18. Identification of HHV8 in early Kaposi's sarcoma pathogenesis
19. Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure
20. Protein tyrosine phosphorylation influences adhesive junction assembly and follicular organisation of cultured thyroid epithelial cells
21. Oncogenes, growth factors, and autoimmune diseases (review)
22. Pathology of the thyroid
23. The thyroid gland
24. Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis
25. Thyroid gland