Prevalence of CagA and VacA antibodies in children with Helicobacter pylori-associated peptic ulcer compared to prevalence in pediatric patients with active or nonactive chronic gastritis

Clinical and Diagnostic Laboratory Immunology

Volumn 7, Issue 5, 2000, Pages 842-844

  Alarcon, T ^a   Martinez, M J ^a   Urruzuno, P ^a   Cilleruelo, M L ^a   Madruga, D ^a   Sebastian, M ^a   Domingo, D ^a   Sanz, J C ^a   Lopez Brea, M ^a  

^a HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY RESPONSE; ANTIGEN DETECTION; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM DETECTION; BLOOD SAMPLING; CHILD; CHRONIC GASTRITIS; FEMALE; HELICOBACTER PYLORI; HUMAN; MAJOR CLINICAL STUDY; MALE; PEDIATRICS; PEPTIC ULCER; PREVALENCE; PRIORITY JOURNAL; SEROCONVERSION; SEROPREVALENCE;

ADOLESCENT; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BLOTTING, WESTERN; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; FEMALE; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; PEPTIC ULCER; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; SEROEPIDEMIOLOGIC STUDIES; SPAIN;

EID: 0033832121     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.7.5.842-844.2000     Document Type: Article

References (19)

1. Pathogenic properties of Helicobacter pylori
2. Use of immunoblot assay to define serum antibody patterns associated with Helicobacter pylori infection and with H. pylori-related ulcers
3. Validation of a serologic test for the diagnosis of Helicobacter pylori infection and the immune response to urease and CagA in children
4. cag, A pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
5. CagA and VacA Status of Spanish Helicobacter pylori clinical isolates
6. Prevalence of CagA, VacA antibodies in symptomatic and asymptomatic children with Helicobacter pylori infection
7. PCR-based diagnosis of Helicobacter pylori infection in Polish children and adults
8. Usefulness of anti-Helicobacter pylori and anti-CagA antibodies in the selection of patients for gastroscopy
9. Importance in diagnosis of gastritis of detection by PCR of the CagA gene in Helicobacter pylori strains isolated from children
10. CagA antibodies in Japanese children with nodular gastritis or peptic ulcer disease
11. Gastric inflammation is enhanced in children with CagA-positive Helicobacter pylori infection
12. Testing for serum IgG antibodies to Helicobacter pylori cytotoxin-associated protein detects children with higher grades of gastric inflammation
13. Major virulence factors, VacA and CagA are commonly positive in Helicobacter pylori isolates in Japan
14. The prevalence of antibody to CagA in children is not a marker for specific disease
15. Equally high prevalences of infection with CagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia
16. The incidence of Helicobacter pylori infection
17. Helicobacter pylori and nonulcer dyspepsia in childhood: Clinical pattern, diagnostic techniques and bacterial strains
18. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
19. Search for putative virulence factors of Helicobacter pylori. The low-molecular-weight (33-35k) antigen