메뉴 건너뛰기




Volumn 7, Issue 5, 2000, Pages 420-428

The action mode of the ribosome-inactivating protein α-sarcin

Author keywords

Ribonuclease; Ribonucleic acid; Ribosome; Ribosome inactivating protein; Rnase T1; Sarcin

Indexed keywords

ALPHA SARCIN; MUTANT PROTEIN; RIBONUCLEASE; RIBOSOME INACTIVATING PROTEIN;

EID: 0033828198     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/BF02255817     Document Type: Article
Times cited : (6)

References (46)
  • 1
    • 0023775256 scopus 로고
    • α-Sarcin causes a specific cut in 28s rRNA when microinjected into Xenopus oocytes
    • Ackerman EJ, Saxena SK, Ulbrich N. α-Sarcin causes a specific cut in 28S rRNA when microinjected into Xenopus oocytes. J Biol Chem 263:17076-17083;1988.
    • (1988) J Biol Chem , vol.263 , pp. 17076-17083
    • Ackerman, E.J.1    Saxena, S.K.2    Ulbrich, N.3
  • 4
    • 0021100286 scopus 로고
    • The sequence of the nucleotides at the α-sarcin cleavage site in rat 28S ribosomal ribonucleic acid
    • Chan YL, Endo Y, Wool IG. The sequence of the nucleotides at the α-sarcin cleavage site in rat 28S ribosomal ribonucleic acid. J Biol Chem 258:12768-12770;1983.
    • (1983) J Biol Chem , vol.258 , pp. 12768-12770
    • Chan, Y.L.1    Endo, Y.2    Wool, I.G.3
  • 5
    • 0029863815 scopus 로고    scopus 로고
    • Substrate specificity of monomeric and dimeric α-sarcin
    • Cheung J-I, Wang Y-R, Lin A. Substrate specificity of monomeric and dimeric α-sarcin. FEBS Lett 386:60-64;1996.
    • (1996) FEBS Lett , vol.386 , pp. 60-64
    • Cheung, J.-I.1    Wang, Y.-R.2    Lin, A.3
  • 6
    • 0345482977 scopus 로고
    • GTP-binding domain: Three consensus sequence elements with distinct spacing
    • Dever TE, Glynias MJ, Merrick W. GTP-binding domain: Three consensus sequence elements with distinct spacing. Proc Natl Acad Sci USA 84:1814-1818;1987.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1814-1818
    • Dever, T.E.1    Glynias, M.J.2    Merrick, W.3
  • 7
    • 0025739807 scopus 로고
    • PCR-mediated chemical mutagenesis of cloned duplex DNAs
    • Diaz J-J, Rhoads DD, Roufad J. PCR-mediated chemical mutagenesis of cloned duplex DNAs. Biotechniques 11:204-209;1991.
    • (1991) Biotechniques , vol.11 , pp. 204-209
    • Diaz, J.-J.1    Rhoads, D.D.2    Roufad, J.3
  • 8
    • 0020479406 scopus 로고
    • The site of action of α-sarcin on eukaryotic ribosomes
    • Endo Y, Wool IG. The site of action of α-sarcin on eukaryotic ribosomes. J Biol Chem 257: 9054-9060;1982.
    • (1982) J Biol Chem , vol.257 , pp. 9054-9060
    • Endo, Y.1    Wool, I.G.2
  • 9
    • 0021111605 scopus 로고
    • The ribonuclease activity of the cytotoxin α-sarcin
    • Endo Y, Huber PW, Wool IG. The ribonuclease activity of the cytotoxin α-sarcin. J Biol Chem 258:2662-2667;1983.
    • (1983) J Biol Chem , vol.258 , pp. 2662-2667
    • Endo, Y.1    Huber, P.W.2    Wool, I.G.3
  • 10
    • 0023917453 scopus 로고
    • The cytotoxins α-sarcin and ricin retain their specificity when tested on a synthetic oligoribonucleotide (35-mer) that mimics a region of 28 S ribosomal ribonucleic acid
    • Endo Y, Chan Y-L, Lin A, Tsurugi K, Wool IG. The cytotoxins α-sarcin and ricin retain their specificity when tested on a synthetic oligoribonucleotide (35-mer) that mimics a region of 28 S ribosomal ribonucleic acid. J Biol Chem 263: 7917-7920;1989.
    • (1989) J Biol Chem , vol.263 , pp. 7917-7920
    • Endo, Y.1    Chan, Y.-L.2    Lin, A.3    Tsurugi, K.4    Wool, I.G.5
  • 11
    • 0025150255 scopus 로고
    • RNA-protein interaction. An analysis with RNA oligonucleotides of the recognition by α-sarcin of a ribosomal domain critical for function
    • Endo Y, Gluck A, Chan Y-L, Tsurugi K, Wool IG. RNA-protein interaction. An analysis with RNA oligonucleotides of the recognition by α-sarcin of a ribosomal domain critical for function. J Biol Chem 265:2216-2222;1990.
    • (1990) J Biol Chem , vol.265 , pp. 2216-2222
    • Endo, Y.1    Gluck, A.2    Chan, Y.-L.3    Tsurugi, K.4    Wool, I.G.5
  • 12
    • 0343898815 scopus 로고    scopus 로고
    • Determination of the 28 S ribosomal RNA identity element (G4319) for alpha-sarcin and the relationship of recognition to selection of the catalytic site
    • Gluck AE, Wool IG. Determination of the 28 S ribosomal RNA identity element (G4319) for alpha-sarcin and the relationship of recognition to selection of the catalytic site. J Mol Biol 256: 838-848;1996.
    • (1996) J Mol Biol , vol.256 , pp. 838-848
    • Gluck, A.E.1    Wool, I.G.2
  • 13
    • 0028864979 scopus 로고
    • Colorimetric investigation of thermal stability and ligand-binding characteristics of disulfide-bond-cleaved ribonuclease T1
    • Haun MF, Wirth M, Ruterjans J. Colorimetric investigation of thermal stability and ligand-binding characteristics of disulfide-bond-cleaved ribonuclease T1. Eur J Biochem 227: 516-523;1995.
    • (1995) Eur J Biochem , vol.227 , pp. 516-523
    • Haun, M.F.1    Wirth, M.2    Ruterjans, J.3
  • 15
    • 0031106798 scopus 로고    scopus 로고
    • Characterization of a new ribotoxin gene (c-sar) from Aspergillus clavatus
    • Huang K-C, Hwang Y-Y, Hwu L, Lin A. Characterization of a new ribotoxin gene (c-sar) from Aspergillus clavatus. Toxicon 35:383-392;1997.
    • (1997) Toxicon , vol.35 , pp. 383-392
    • Huang, K.-C.1    Hwang, Y.-Y.2    Hwu, L.3    Lin, A.4
  • 17
    • 0024995219 scopus 로고
    • Self-splicing group II and nuclear pre-mRNA introns: How similar are they?
    • Jacquier A. Self-splicing group II and nuclear pre-mRNA introns: How similar are they? Trends Biochem Sci 15:351-354;1990.
    • (1990) Trends Biochem Sci , vol.15 , pp. 351-354
    • Jacquier, A.1
  • 18
    • 0029402948 scopus 로고
    • Fungal ribotoxins: A family of naturally engineered targeted toxins
    • Kao R, Davies J. Fungal ribotoxins: A family of naturally engineered targeted toxins. Biochem Cell Biol 73:1151-1169;1995.
    • (1995) Biochem Cell Biol , vol.73 , pp. 1151-1169
    • Kao, R.1    Davies, J.2
  • 19
    • 0031816245 scopus 로고    scopus 로고
    • Probing the active site of mitogillin, a fungal ribotoxin
    • Kao R, Shea JE, Davies J, Holden DW. Probing the active site of mitogillin, a fungal ribotoxin. Mol Microbiol 29:1019-1027;1998.
    • (1998) Mol Microbiol , vol.29 , pp. 1019-1027
    • Kao, R.1    Shea, J.E.2    Davies, J.3    Holden, D.W.4
  • 20
    • 0033617455 scopus 로고    scopus 로고
    • Molecular dissection of mitogillin reveals that the fungal ribotoxins are a family of natural genetically engineered ribonucleases
    • Kao R, Davies J. Molecular dissection of mitogillin reveals that the fungal ribotoxins are a family of natural genetically engineered ribonucleases. J Biol Chem 274:12576-12582; 1999.
    • (1999) J Biol Chem , vol.274 , pp. 12576-12582
    • Kao, R.1    Davies, J.2
  • 21
    • 0025761656 scopus 로고
    • RNA recognition: Towards identifying determinants of specificity
    • Kenan DJ, Query CC, Keene JD. RNA recognition: Towards identifying determinants of specificity. Trends Biochem Sci 16:214-220; 1991.
    • (1991) Trends Biochem Sci , vol.16 , pp. 214-220
    • Kenan, D.J.1    Query, C.C.2    Keene, J.D.3
  • 24
    • 0026062588 scopus 로고
    • Isolation and nucleotide sequence of the Aspergillus restrictus gene coding for the ribonucleolytic toxin restrictocin and its expression in Aspergillus nidulans: The leader sequence protects producing strains from suicide
    • Lamy B, Davies J. Isolation and nucleotide sequence of the Aspergillus restrictus gene coding for the ribonucleolytic toxin restrictocin and its expression in Aspergillus nidulans: The leader sequence protects producing strains from suicide. Nucleic Acids Res 19:1001-1006;1991.
    • (1991) Nucleic Acids Res , vol.19 , pp. 1001-1006
    • Lamy, B.1    Davies, J.2
  • 25
    • 0028198937 scopus 로고
    • Yolk granules are the major compartment for bullfrog (Rana catesbeiana) oocyte-specific ribonuclease
    • Liao Y-D, Wang J-J. Yolk granules are the major compartment for bullfrog (Rana catesbeiana) oocyte-specific ribonuclease. Eur J Biochem 222:215-220;1994.
    • (1994) Eur J Biochem , vol.222 , pp. 215-220
    • Liao, Y.-D.1    Wang, J.-J.2
  • 26
    • 0027997921 scopus 로고
    • Hydrolysis of ribosomes by electrophoretically blotted ribotoxin
    • Lin A, Huang R-G. Hydrolysis of ribosomes by electrophoretically blotted ribotoxin. Biotechniques 17:636-637;1994.
    • (1994) Biotechniques , vol.17 , pp. 636-637
    • Lin, A.1    Huang, R.-G.2
  • 27
    • 0028953955 scopus 로고
    • Production of type II ribotoxins by Aspergillus species and related fungi in Taiwan
    • Lin A, Huang K-C, Hwu L, Tzean SS. Production of type II ribotoxins by Aspergillus species and related fungi in Taiwan. Toxicon 33:105-110;1995.
    • (1995) Toxicon , vol.33 , pp. 105-110
    • Lin, A.1    Huang, K.-C.2    Hwu, L.3    Tzean, S.S.4
  • 28
    • 0028364637 scopus 로고
    • Cleavage of super-coiled double-stranded DNA by several ribosome-inactivating proteins in vitro
    • Ling J, Liu W, Wang TP. Cleavage of super-coiled double-stranded DNA by several ribosome-inactivating proteins in vitro. FEBS Lett 345:143-146;1994.
    • (1994) FEBS Lett , vol.345 , pp. 143-146
    • Ling, J.1    Liu, W.2    Wang, T.P.3
  • 29
    • 0028931195 scopus 로고
    • Predictive study of the conformation of cytotoxic protein α-sarcin: A structural model to explain α-sarcin-membrane interaction
    • Mancheno JM, Gasse M, Lacadena J, Martinez del Pozo A, Onaderra M, Gavilanes JG. Predictive study of the conformation of cytotoxic protein α-sarcin: A structural model to explain α-sarcin-membrane interaction. J Theor Biol 172:259-267;1995.
    • (1995) J Theor Biol , vol.172 , pp. 259-267
    • Mancheno, J.M.1    Gasse, M.2    Lacadena, J.3    Martinez Del Pozo, A.4    Onaderra, M.5    Gavilanes, J.G.6
  • 31
    • 0026357217 scopus 로고
    • Ribonuclease T1 with free recognition and catalytic site: Crystal structure analysis at 1.5 Å resolution
    • Martinez-Oyanedel J, Choe HW, Heinemann U, Saenger W. Ribonuclease T1 with free recognition and catalytic site: Crystal structure analysis at 1.5 Å resolution. J Mol Biol 222: 335-352;1991.
    • (1991) J Mol Biol , vol.222 , pp. 335-352
    • Martinez-Oyanedel, J.1    Choe, H.W.2    Heinemann, U.3    Saenger, W.4
  • 32
    • 0025907657 scopus 로고
    • α-Sarcin cleavage of ribosomal RNA is inhibited by binding of elongation factor G or thiostrepton to the ribosome
    • Miller SP, Bodley JW. α-Sarcin cleavage of ribosomal RNA is inhibited by binding of elongation factor G or thiostrepton to the ribosome. Nucleic Acids Res 19:1657-1660;1991.
    • (1991) Nucleic Acids Res , vol.19 , pp. 1657-1660
    • Miller, S.P.1    Bodley, J.W.2
  • 33
    • 0026509828 scopus 로고
    • An efficient expression system for a variant form of the cytotoxic protein α-sarcin in Escherichia coli
    • Oka T, Aoyama Y, Natori Y, Katano T, Endo Y. An efficient expression system for a variant form of the cytotoxic protein α-sarcin in Escherichia coli. Biochim Biophys Acta 1130:182-188;1992.
    • (1992) Biochim Biophys Acta , vol.1130 , pp. 182-188
    • Oka, T.1    Aoyama, Y.2    Natori, Y.3    Katano, T.4    Endo, Y.5
  • 34
    • 0023783477 scopus 로고
    • Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bonds
    • Pace CN, Grimsley GR, Thomson JA, Barnett BJ. Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bonds. J Biol Chem 263:11820-11825;1988.
    • (1988) J Biol Chem , vol.263 , pp. 11820-11825
    • Pace, C.N.1    Grimsley, G.R.2    Thomson, J.A.3    Barnett, B.J.4
  • 36
    • 0020586939 scopus 로고
    • The primary structure of the cytotoxin α-sarcin
    • Sacco G, Drickamer K, Wool IG. The primary structure of the cytotoxin α-sarcin. J Biol Chem 258:5811-5818;1983.
    • (1983) J Biol Chem , vol.258 , pp. 5811-5818
    • Sacco, G.1    Drickamer, K.2    Wool, I.G.3
  • 37
    • 0017334489 scopus 로고
    • Specific cleavage of ribosomal RNA by alpha sarcin
    • Schindler DG, Davies JE. Specific cleavage of ribosomal RNA by alpha sarcin. Nucleic Acids Res 4:1097-1110;1977.
    • (1977) Nucleic Acids Res , vol.4 , pp. 1097-1110
    • Schindler, D.G.1    Davies, J.E.2
  • 38
    • 0025325256 scopus 로고
    • Comparison of active sites of some microbial ribonucleascs: Structural basis for guanylic specificity
    • Sevcik J, Sanishvili RG, Pavlovsky AG, Polyakov KM. Comparison of active sites of some microbial ribonucleascs: Structural basis for guanylic specificity. Trends Biochem Sci 15: 158-62;1990.
    • (1990) Trends Biochem Sci , vol.15 , pp. 158-162
    • Sevcik, J.1    Sanishvili, R.G.2    Pavlovsky, A.G.3    Polyakov, K.M.4
  • 39
    • 0030877826 scopus 로고    scopus 로고
    • A decade of protein engineering on ribonuclease T1: Atomic dissection of the enzyme-substrate interactions
    • Steyaert J. A decade of protein engineering on ribonuclease T1: Atomic dissection of the enzyme-substrate interactions. Eur J Biochem 247:1-11;1997.
    • (1997) Eur J Biochem , vol.247 , pp. 1-11
    • Steyaert, J.1
  • 40
    • 0025935551 scopus 로고
    • On the conformation of the alpha sarcin stemloop of 28S rRNA
    • Szewczak AA, Chan YL, Moor PB, Wool IG. On the conformation of the alpha sarcin stemloop of 28S rRNA. Biochimie 78:871-877; 1991.
    • (1991) Biochimie , vol.78 , pp. 871-877
    • Szewczak, A.A.1    Chan, Y.L.2    Moor, P.B.3    Wool, I.G.4
  • 41
    • 0028953727 scopus 로고
    • The sarcin/ricin loop, a modular RNA
    • Szewczak AA, Moore PB. The sarcin/ricin loop, a modular RNA. J Mol Biol 247:81-98; 1995.
    • (1995) J Mol Biol , vol.247 , pp. 81-98
    • Szewczak, A.A.1    Moore, P.B.2
  • 42
    • 0027523140 scopus 로고
    • Characterization of the gene encoding α-sarcin, a ribosome-inactivating protein secreted by Aspergillns giganteus
    • Wnendt S, Felske-Zech H, Henze P-PC, Ulbrich N, Stahl U. Characterization of the gene encoding α-sarcin, a ribosome-inactivating protein secreted by Aspergillns giganteus. Gene 124:239-244;1993.
    • (1993) Gene , vol.124 , pp. 239-244
    • Wnendt, S.1    Felske-Zech, H.2    Henze, P.-P.C.3    Ulbrich, N.4    Stahl, U.5
  • 43
    • 48749139837 scopus 로고
    • The mechanism of action of the cytotoxic nuclease α-sarcin and its use to analyse ribosome structure
    • Wool IG. The mechanism of action of the cytotoxic nuclease α-sarcin and its use to analyse ribosome structure. Trends Biochem Sci 9:14-17;1984.
    • (1984) Trends Biochem Sci , vol.9 , pp. 14-17
    • Wool, I.G.1
  • 44
    • 0026690643 scopus 로고
    • Ribotoxin recognition of ribosomal RNA and a proposal for the mechanism of translocation
    • Wool IG, Gluck A, Endo Y. Ribotoxin recognition of ribosomal RNA and a proposal for the mechanism of translocation. Trends Biochem Sci 17:266-269;1992.
    • (1992) Trends Biochem Sci , vol.17 , pp. 266-269
    • Wool, I.G.1    Gluck, A.2    Endo, Y.3
  • 45
    • 0026785718 scopus 로고
    • Effects of amino-terminal extensions and specific mutations on the activity of restrictocin
    • Yang R, Kenealy W. Effects of amino-terminal extensions and specific mutations on the activity of restrictocin. J Biol Chem 267:16801-16805;1992.
    • (1992) J Biol Chem , vol.267 , pp. 16801-16805
    • Yang, R.1    Kenealy, W.2
  • 46
    • 0030586029 scopus 로고    scopus 로고
    • Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin
    • Yang X, Moffat K. Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin. Structure 4:837-852;1996.
    • (1996) Structure , vol.4 , pp. 837-852
    • Yang, X.1    Moffat, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.