Arsenite-resistant Leishmania donovani promastigotes express an enhanced membrane P-type adenosine triphosphatase activity that is sensitive to verapamil treatment

Parasitology Research

Volumn 86, Issue 8, 2000, Pages 661-664

  Prasad, Vikram ^a   Kaur, Jaspreet ^a   Dey, Chinmoy S ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ARSENITE SODIUM; DOXORUBICIN; PENTAMIDINE;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG TRANSPORT; ENZYME ACTIVITY; IC 50; LEISHMANIA DONOVANI; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN EXPRESSION; STRAIN DIFFERENCE;

EID: 0033826522     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00008548     Document Type: Article

References (25)

1. The beta-aspartyl phosphate intermediate in a Leishmania donovani promastigote plasma membrane P-type ATPase
2. Estimation of population at risk of infection and number of cases of leishmaniasis
3. New mechanisms of drug resistance in parasitic protozoa
4. Heavy metal resistance: A new role for P-glycoproteins in Leishmania
5. Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line
6. Cloning and functional analysis of an extrachromosomally amplified multi-drug resistance-like gene in Leishmania enriettii
7. An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae
8. Leishmania (V.) guyanensis: Isolation and characterization of glucantime-resistant cell lines
9. Pharmacology of drugs that alter multidrug resistance in cancer
10. P-glycoprotein overexpression in methotrexate-resistant Leishmania tropica
11. Characteristics of multidrug resistance in Plasmodium and Leishmania: Detection of P-glycoprotein-like components
12. Leishmania amazonensis: Multidrug resistance in vinblastine-resistant promastigotes is associated with rhodamine 123 efflux, DNA amplification, and RNA overexpression of a Leishmania mdr I gene
13. Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ ADM cells
14. Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr I gene
15. ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells
16. Quantitative in vitro drug potency and drug susceptibility evaluation of Leishmania spp. from patients unresponsive to pentavalent antimony therapy
17. The P-glycoprotein-related gene family in Leishmania
18. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity
19. Evidence for transcriptional control of human mdr I gene expression by verapamil in multidrug-resistant leukemic cells
20. Reversal of drug resistance in Trypanosoma cruzi and Leishmania donovani by verapamil
21. Contribution of the Leishmania P-glycoprotein-related gene ItpgpA to oxyanion resistance
22. Gene disruption of the P-glycoprotein related gene pgpA of Leishmania tarentolae
23. Resistance mechanisms to arsenicals and anti-monials
24. Increased P-type AT-Pase activity in Leishmania tropica resistant to methotrexate
25. Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil