Elevated homocysteine levels are associated with increased ischemic myocardial injury in acute coronary syndromes

Journal of the American College of Cardiology

Volumn 36, Issue 4, 2000, Pages 1217-1222

  Al Obaidi, Mohamed K ^a,d   Stubbs, Peter J ^a   Collinson, Paul ^b   Conroy, Ronan ^c   Graham, Ian ^c   Noble, Mark I M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b MAYDAY UNIVERSITY HOSPITAL   (United Kingdom)

^c ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^d ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOCYSTEINE; TROPONIN T;

ADULT; AGE; ARTICLE; BLOOD LEVEL; CORRELATION FUNCTION; DISEASE ASSOCIATION; FEMALE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; PLASMA; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; THROMBOSIS; UNSTABLE ANGINA PECTORIS;

ANGINA, UNSTABLE; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPARATIVE STUDY; CORONARY ANGIOGRAPHY; CREATINE KINASE; ELECTROCARDIOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HOMOCYSTEINE; HUMAN; HYDROXYBUTYRATE DEHYDROGENASE; MALE; MIDDLE AGE; MYOCARDIAL INFARCTION; MYOCARDIUM; PROGNOSIS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SUPPORT, NON-U.S. GOV'T; TROPONIN T;

EID: 0033819959     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(00)00820-2     Document Type: Article

References (27)

1. Hyperhomocysteinemia: An independent risk factor for vascular disease
2. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians
3. Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis
4. Homocysteine and thrombotic disease
5. The natural history of homocystinuria due to cystathionine β-synthase deficiency
6. Plasma homocysteine levels and mortality in patients with coronary artery disease
7. Clinical-pathological correlations of coronary disease progression and regression
8. Relationships between homocysteine, Factor VIIa and thrombin generation in acute coronary syndromes
9. Troponin T for the differential diagnosis of ischaemic myocardial damage
10. Fully automated fluorescence assay for determining total homocysteine in plasma
11. Homocysteine and other thiols in plasma and urine: Automated determination and sample stability
12. Serial measures of plasma homocyst(e)ine after acute myocardial infarction
13. Homocysteine and fibrinolysis in acute occlusive coronary events
14. Cardiac troponin T levels for risk stratification in acute myocardial ischemia
15. Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease. The FRISC study group
16. Prospective study of the role of cardiac troponin T in patients with unstable angina
17. Prognostic significance of admission troponin T concentrations in patients with myocardial infarction
18. Acute and convalescent changes in plasma homocysteine concentrations in the acute coronary syndromes
19. Factors influencing infarct size following experimental coronary artery occlusions
20. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
21. Hyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunction in humans
22. Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults
23. Diagnostic efficiency of troponin T measurements in acute myocardial infarction
24. Analysis of creatine kinase, CK-MB, myoglobin and troponin T time-activity curves for early assessment of coronary artery reperfusion after intravenous thrombolysis
25. Cardiac troponin T release in acute myocardial infarction is associated with scintigraphic estimates of myocardial scar
26. The effect of plasma homocysteine concentration on early and late events in patients with acute coronary syndromes