Intranasal treatment of cowpox virus respiratory infections in mice with cidofovir

Antiviral Research

Volumn 47, Issue 3, 2000, Pages 171-177

  Smee, Donald F ^a   Bailey, Kevin W ^a   Wong, Min Hui ^a   Sidwell, Robert W ^a  

^a UTAH STATE UNIVERSITY   (United States)

Author keywords

Antiviral; Cidofovir; Cowpox virus; Intranasal treatment

Indexed keywords

ANTIVIRUS AGENT; CIDOFOVIR; ZANAMIVIR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COWPOX VIRUS; DOSE RESPONSE; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SURVIVAL RATE; TREATMENT OUTCOME; VIRUS INFECTION; VIRUS INHIBITION;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; COWPOX; COWPOX VIRUS; CYTOSINE; FEMALE; MICE; MICE, INBRED BALB C; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; PLAQUE ASSAY; RESPIRATORY SYSTEM; RESPIRATORY TRACT INFECTIONS; VERO CELLS;

EID: 0033819235     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(00)00105-4     Document Type: Article

References (15)

1. Bray M., Martinez M., Smee D.F., Kefauver D., Thompson E., Huggins J.W. Cidofovir (HPMPC) protects mice against lethal aerosol or intranasal cowpox virus challenge. J. Infect. Dis. 181:2000;10-19.
2. Breman J.G., Henderson D.A. Poxvirus dilemmas-monkeypox, smallpox and biological terrorism. New Engl. J. Med. 339:1998;556-559.
3. De Clercq E., Luczak M., Shugar D., Torrence P.F., Waters J.A., Witkop B. Effect of cytosine arabinoside, iododeoxyuridine, ethyldeoxyuridine, thiocyanatodeoxyuridine, and ribavirin on tail lesion formation in mice infected with vaccinia virus. Proc. Soc. Exp. Biol. Med. 151:1976;487-490.
4. Hitchcock M.J.M., Jaffe H.S., Martin J.C., Stagg R.J. Cidofovir, a new agent with potent anti-herpesvirus activity. Antiviral Chem. Chemother. 7:1996;115-127.
5. Kesson A.M., Ferguson J.K., Rawlinson W.D., Cunningham A.L. Progressive vaccinia treated with ribavirin and vaccinia immune globulin. Clin. Infect. Dis. 25:1997;911-914.
6. Martinez M.J., Bray M.P., Huggins J.W. A mouse model of aerosol-transmitted orthopoxviral disease: morphology of experimental aerosol-transmitted orthopoxviral disease in a cowpox virus-BA:B/c mouse system. Arch. Pathol. Lab. Med. 124:2000;362-377.
7. Meadows K.P., Tyring S.K., Pavia A.T., Rallis T.M Resolution of recalcitrant molluscum contagiosum virus lesions in human immunodeficiency virus-infected patients treated with cidofovir. Arch. Dermatol. 133:1997;987-990.
8. Monto A.S., Fleming D.M., Henry D. et al. Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenza A and B virus infections. J. Infect. Dis. 180:1999;254-261.
9. Naesens L., Snoeck R., Andrei G., Balzarini J., Neyts J., De Clercq E. HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogues: a review of their pharmacology and clinical potential in the treatment of viral infections. Antiviral Chem. Chemother. 8:1997;1-23.
10. Neyts J., De Clercq E. Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice. J. Med. Virol. 41:1993;242-246.
11. Orent W. Escape from Moscow. The Sciences. 1998:1998;26-31.
12. Smee D.F., Alaghamandan H.A., Bartlett M.L., Robins R.K. Intranasal treatment of picornavirus and coronavirus respiratory infections in rodents using 7-thia-8-oxoguanosine. Antiviral Chem. Chemother. 1:1990;47-52.
13. Smee D.F., Huggins J.W. Potential of the IMP dehydrogenase inhibitors for antiviral therapies of poxvirus infections. Antiviral Res. 37:1998;A89.
14. Wachsman M., Petty B.G., Cundy K.C. et al. Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects. Antiviral Res. 29:1996;153-161.
15. Woods J.M., Bethell R.C., Coates J.A.V et al. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-Acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro. Antimicrob. Agents Chemother. 37:1993;1473-1479.