A sensitive screening assay for secreted motility-stimulating factors

Cell Motility and the Cytoskeleton

Volumn 46, Issue 4, 2000, Pages 279-284

  Nam, Suk Woo ^a   Clair, Timothy ^a   Schiffmann, Elliott ^a   Liotta, Lance A ^a   Stracke, Mary L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Autocrine motility factor; Autotaxin; Boyden chamber; Chemotaxis; Motility

Indexed keywords

AUTOTAXIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CELL LINE; CELL MOTILITY; CELL STRAIN 3T3; CHEMOTAXIS; CONTROLLED STUDY; DENSITOMETRY; DNA TRANSFECTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SECRETION;

3T3 CELLS; ANIMALS; AUTOCRINE MOTILITY FACTOR; BIOLOGICAL ASSAY; CELL MOVEMENT; CHEMOTAXIS; CULTURE MEDIA, CONDITIONED; GLYCOPROTEINS; HUMANS; MELANOMA; MICE; MULTIENZYME COMPLEXES; PHOSPHODIESTERASE I; PYROPHOSPHATASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033817032     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0169(200008)46:4<279::AID-CM5>3.0.CO;2-P     Document Type: Article

References (23)

1. Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type a and type b transforming growth factors
2. Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities
3. Mechanisms responsible for the origin and distribution of blood-borne tumor metastases: A review
4. The amoeboid motility of human and animal neoplastic cells
5. Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement
6. Nucleotide sequences of cDNAs encoding precursors of human insulin-like growth factor II (IGF-II) and an IGF-II variant
7. Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells
8. Tumor cell autocrine motility factor
9. Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells
10. Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor
11. Cyclocreatine inhibits stimulated motility in tumor cells possessing creatine kinase
12. cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases
13. Molecular cloning and expression of human hepatocyte growth factor
14. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras -transformed cells
15. Expression and secretion of neuroleukin/phosphohexose isomerase/maturation factor as autocrine motility factor by tumor cells
16. Studies of Polynucleotides III. Enzymic degradation, substrate specificity and properties of snake venom phosphodiesterase
17. Primary structure of human insulin-like growth factor II
18. The directed migration of eukaryotic cells
19. Molecular mechanisms of tumor cell metastasis
20. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein
21. Transforming growth factors produced by certain human tumor cells: Polypeptides that interact with epidermal growth factor receptors
22. Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide
23. Autotaxin expression in non-small-cell lung cancer