Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells

Journal of Biological Chemistry

Volumn 271, Issue 41, 1996, Pages 25107-25116

  MacDonald, Nicholas J ^a   Freije, José M P ^a,b   Stracke, Mary L ^a   Manrow, Richard E ^a,c   Steeg, Patricia S ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b Span Min de Educacion Y Cie ^*

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; NUCLEOSIDE DIPHOSPHATE KINASE;

AMINO ACID SEQUENCE; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; METASTASIS INHIBITION; PRIORITY JOURNAL; PROTEIN DETERMINATION; SITE DIRECTED MUTAGENESIS;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; BREAST NEOPLASMS; CELL DIVISION; CHEMOTAXIS; DROSOPHILA; FEMALE; GLYCINE; HISTIDINE; HUMANS; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; MUTAGENESIS, SITE-DIRECTED; NEUROBLASTOMA; NUCLEOSIDE-DIPHOSPHATE KINASE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROLINE; RECOMBINANT PROTEINS; SERINE; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0029819176     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.41.25107     Document Type: Article

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