Effect of dilute acetic acid on rat gastric mucosa following acute and chronic administration - Induction of adaptive cytoprotection

Japanese Pharmacology and Therapeutics

Volumn 28, Issue 6, 2000, Pages 473-480

  Kawauchi, S ^a   Mimaki, H ^a   Kitazaki, H ^a   Takeuchi, K ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Acetic acid; Adaptive cytoprotection; Ethanol; Prostaglandins; Stomach

Indexed keywords

ACETIC ACID; ALCOHOL; HYDROCHLORIC ACID; INDOMETACIN; N(G) NITROARGININE METHYL ESTER;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; NONHUMAN; RAT; STOMACH BLOOD FLOW; STOMACH MUCOSA LESION; STOMACH PROTECTION;

EID: 0033815744     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Cytoprotection by prostaglandins in rats: Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl and thermal injury
2. Role of locally generated prostaglandins in adaptive gastric cytoprotection
3. Mild irritants prevent gastric necrosis through 'adaptive cytoprotection' mediated by prostaglandins
4. Irritative and protective activity of mild irritants in the rat stomach
5. Regulation of gastric mucosal integrity by endogenous nitric oxide: Interactions with prostanoids and sensory neuropeptides in the rat
6. Vinega is a dietary mild irritant to the rat gastric mucosa
7. Role of capsaicin-sensitive afferent neurons in alkaline secretory response to luminal acid in the rat duodenum
8. A continuous monitoring of mucosal integrity and secretory activity in rat stomach : A preparation using a lucite chamber
9. Cyclooxygenase isozymes in acute mucosal ulcerogenic and functional responses following barrier disruption in rat stomachs
10. Effects of prostaglandins on the digestive system
11. Aspirin-induced human antral injury is reduced by vodka pretreatment
12. The differential mechanisms of mild irritants on adaptive cytoprotection
13. Role of eicosanoids, nitric oxide, and afferent neurons in antacid induced protection in the rat stomach
14. Effects of chronic superficial injury on the rat gastric mucosa
15. 2
16. Role of nitric oxide in restitution of injured guinea pig gastric mucosa in vitro
17. Restitution of frog gastric mucosa in vitro : Effect of basic fibroblast growth factor
18. Role of capsaicin-sensitive afferent neurons in mucosal blood flow response of rat stomach induced by mild irritants
19. Sensory neurons mediate protective vasodilatation in rat gastric mucosa
20. Calcitonin gene-related peptide mediates the gastric hyperemic response to acid back-diffusion
21. Participation of endothelium-derived nitric oxide but not prostacyclin in the gastric mucosa hyperemia due to acid back-diffusion
22. The role of capsaicin-sensitive sensory neurons in healing of HCl-induced gastric mucosal lesions in rats
23. The capsaicin receptor : A heat-activated ion channel in the pain pathway
24. Stimulation of prostaglandin output from rat stomach by hypertonic solutions
25. Antiulcer activity of hypertonic solutions in the rat : Possible role of prostaglandins