Homozygous HLA-G*0105N healthy individuals indicate that membrane-anchored HLA-G1 molecule is not necessary for survival

Tissue Antigens

Volumn 56, Issue 3, 2000, Pages 232-239

  Castro, M J ^a   Morales, P ^a   Rojo Amigo, R ^a   Martinez Laso, J ^a   Allende, L ^a   Varela, P ^a   Garcia Berciano, M ^a   Guillen Perales, J ^a   Arnaiz Villena, A ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Alternative splicing; Evolution; HLA G; Null allele

Indexed keywords

HLA G ANTIGEN; MEMBRANE PROTEIN; MESSENGER RNA;

ADULT; ALTERNATIVE RNA SPLICING; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNITY; CHILD; FEMALE; FETUS DEVELOPMENT; HOMOZYGOSITY; HUMAN; IMMUNE DEFICIENCY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PRIORITY JOURNAL; PROTEIN DOMAIN; STOP CODON;

ALLELES; ALTERNATIVE SPLICING; BASE SEQUENCE; DNA, COMPLEMENTARY; FAMILY HEALTH; FEMALE; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-C ANTIGENS; HOMOZYGOTE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; PEDIGREE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTEIN ISOFORMS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE DELETION;

EID: 0033811849     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0039.2000.560305.x     Document Type: Article

References (39)

1. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment
2. Identification of a thymic epithelial cell subset sharing expression of the class Ib HLA-G molecule with fetal trophoblasts
3. Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA class I molecule
4. Characterization of an expressible nonclassical class I HLA gene
5. Lack of HLA-G soluble isoforms in Graves-Basedow thyrocytes and complete cDNA sequence of the HLA-G*01012 allele
6. Three new HLA-G alleles and their linkage disequilibria with HLA-A
7. Population genetics studies of HLA-G: Allele frequencies and linkage disequilibrium with HLA-A
8. HLA-G gene polymorphism in a Japanese population
9. A new HLA-G allele (HLA-G*0105N) and its distribution in the Spanish population
10. Re-examination of HLA-G polymorphism in African American
11. Little evidence of HLA-G mRNA polymorphism in Caucasian or Afro-Caribbean population
12. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens
13. The functionality of HLA-G is emerging
14. The ILT2 (LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells
15. Human myelomonocytic cells extress an inhibitory receptor for classical and nonclassical MHC class I molecules
16. p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily
17. HLA-G: A tolerance molecule from the major histocompatibility complex
18. Nonclassical HLA-G molecules are classical peptide presenters
19. HLA-E bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: Preferential response to an HLAG derived nonamer
20. HLA-G1 protein expression is not essential for fetal survival
21. Primate HLA-E and -G alleles
22. HLA-G gene polymorphism segregation within CEPH reference families
23. HLA-G polymorphism: Neutral evolution or novel function?
24. HLA-G polymorphism and allelic association with HLA-A in Finnish population
25. HLA-G polymorphism: 12th International Histocompatibility Workshop study
26. B lymphocyte isolation by thrombinnylonwool
27. Detection of HLA-E and -G alleles for population and disease studies
28. Molecular clonning: A laboratory manual
29. The HLA-G gene is expressed at a low mRNA level in different human cells and tissues
30. Primary immunodeficiency caused by mutations in the gene encoding the CD3-γ subunit of the T lymphocyte receptor
31. HLA-G and HLA-C at the feto-maternal interface: Lessons learned from pathogenic viruses
32. The contribution of the HLA-A, -B, -C and -DR, -DQ DNA typing to the study of the origins of Spaniards and Basques
33. HLA allele and haplotype frecuencies in Algerians. Relatedness to Spaniards and Basques
34. The origin of Cretan populations as determined by characterization of HLA alleles
35. The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association
36. HLA·G polymorphisms in African American
37. Identification of the Rhesus monkey HLA-G ortolog. Mamu-G is a pseudogene
38. Allelic diversity at the primate Mhc-G locus: Exon 3 bears stop codons in all Cercopithecinae sequences
39. An evolutive overview of the MHC·G polymorphism: Clues about the unknown function(s)