Mutations in multidrug efflux homologs, sugar isomerases, and antimicrobial biosynthesis genes differentially elevate activity of the σ(x) and σ(w) factors in Bacillus subtilis

Journal of Bacteriology

Volumn 182, Issue 18, 2000, Pages 5202-5210

  Turner, M S ^a   Helmann, J D ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL DNA; CARRIER PROTEIN; DIFFICIDIN; ISOMERASE; MANNOSE PHOSPHATE ISOMERASE; MEMBRANE PROTEIN; MUTANT PROTEIN; OLIGOPEPTIDE; POLYKETIDE; RHAMNOSE; SIGMA FACTOR; UNCLASSIFIED DRUG;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACILLUS SUBTILIS; BACTERIAL MEMBRANE; CARBOHYDRATE METABOLISM; CELL DENSITY; CONTROLLED STUDY; DNA SEQUENCE; DRUG TRANSPORT; GENE INSERTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE HOMOLOGY; TRANSPOSON;

BACILLUS SUBTILIS;

EID: 0033810986     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.18.5202-5210.2000     Document Type: Article

References (69)

1. Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated
2. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
3. Transcriptional regulation of ferric citrate transport in Escherichia coli K·12. FecI belongs to a new subfamily of sigma-70-type factors that respond to extracytoplasmic stimuli
4. Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes
5. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
6. Metalloregulation in Bacillus subtilis: Isolation and characterization of two genes differentially regulated by metal ions
7. Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis
8. The σ(E) and the Cpx signal transduction systems control the synthesis of periplasmic protein-folding enzymes in Escherichia coli
9. Identification of comS, a gene of the srfA operon that regulates the establishment of genetic competence in Bacillus subtilis
10. CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258
11. The sialic acids. IV. N-Acyl-D-glucosamine-6-phosphate 2-epimerase
12. 2+ transport system
13. Bacillus subtilis routs mutL operon: Identification, nucleotide sequence and mutagenesis
14. Complete structure of the adhesin receptor polysaccharide of Streptococcus oralis ATCC 55229 (Streptococcus sanguis H1)
15. The sigma factors of Bacillus subtilis
16. Involvement of superoxide dismutase in spore coat assembly in Bacillus subtilis
17. The algT (algU) gene of Pseudomonas aeruginosa, a key regulator involved in alginate biosynthesis, encodes an alternative sigma factor σ(E)
18. TMbase - A database of membrane spanning protein segments
19. σ(M), an ECF RNA polymerase sigma factor of Bacillus subtilis 168, is essential for growth and survival in high concentrations of salt
20. The Bacillus subtilis σ(X) protein is an extracytoplasmic function sigma factor contributing to the survival of high temperature stress
21. Promoter recognition by Bacillus subtilis σ(W): Autoregulation and partial overlap with the σ(X) regulon
22. Identification of target promoters for the Bacillus subtilis extracytoplasmic function σ factor, σ(W)
23. Identification of target promoters for the Bacillus subtilis σ(X) factor using a consensus-directed search
24. Isolation of a prokaryotic metallothionein locus analysis of transcriptional control by trace metal ions
25. Sigma-E is required for the production of the antibiotic actinomycin in Streptomyces antibioticus
26. Molecular analysis of the phoH gene, belonging to the phosphate regulon in Escherichia coli
27. The complete genome sequence of the gram-positive bacterium Bacillus subtilis
28. An exported peptide functions intracellularly to contribute to cell density signaling in B. subtilis
29. Characterization of the inducible nickel and cobalt resistance determinant cnr from pMOL28 of Alcaligenes eutrophus CH34
30. Role of crotonyl coenzyme A reductase in determining the ratio of polyketides monensin A and monensin B produced by Streptomyces cinnamonensis
31. Analysis of the Streptomyces coelicolor sigE gene reveals the existence of a subfamily of eubacterial σ factors involved in the regulation of extracytoplasmic functions
32. Identification, expression, and DNA sequence of the GDP-mannose biosynthesis genes encoded by the O7 rfb gene cluster of strain VW187 (Escherichia coli O7:K1)
33. Cloning and sequencing of a novel meta-cleavage dioxygenase gene whose product is involved in degradation of gamma-hexachlorocyclohexane in Sphingomonas paucimobilis
34. Sequencing and characterization of a gene duster encoding the enzymes for L-rhamnose metabolism in Escherichia coli
35. SubtiList: A relational database for the Bacillus subtilis genome
36. Expert system for predicting protein localization sites in gram-negative bacteria
37. Identification of a genetic locus required for biosynthesis of the lipopeptide antibiotic surfactin in Bacillus subtilis
38. Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous
39. Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated pvdS gene encoding an alternative sigma factor
40. PcpA, which is involved in the degradation of pentachlorophenol in Sphingomonas chlorophenolica ATCC39723, is a novel type of ring-cleavage dioxygenase
41. σ(R), an RNA polymerase sigma factor that modulates expression of the thioredoxin system in response to oxidative stress in Streptomyces coelicolor A3(2)
42. Evidence that the extracytoplasmic function sigma factor σ(E) is required for normal cell wall structure in Streptomyces coelicolor A3(2)
43. Identification of σ(B)-dependent genes in Bacillus subtills using a promoter consensus-directed search and oligonucleotide hybridization
44. Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases
45. Inventory, assembly and analysis of Bacillus subtilis ABC transport systems
46. Identification and molecular analysis of the gene encoding Rickettsia typhi hemolysin
47. Analysis of genes involved in biosynthesis of coronafacic acid, the polyketide component of the phytotoxin coronatine
48. Novel phosphotransferase system genes revealed by genome analysis - The complete complement of PTS proteins encoded within the genome of Bacillus subtilis
49. Expression and regulation of the antimonite, arsenite, and arsenate resistance operon of Staphylococcus xylosus plasmid pSX267
50. The spoOK locus of Bacillus subtilis is homologous to the oligopeptide permease locus and is required for sporulation and competence
51. Isolation and sequence analysis of the pmi gene encoding phosphomannose isomerase of Streptococcus mutans
52. Identification of a putative metal binding site in a new family of metalloregulatory proteins
53. Mutations that relieve nutritional repression of the Bacillus subtilis dipeptide permease operon
54. Easy cloning of mini-Tn10 insertions from the Bacillus subtilis chromosome
55. Molecular analyses of the lactococcin A gene cluster from Lactococcus lactis subsp. lactis biovar diacetylactis WM4
56. Cloning, nucleotide sequence, and characterization of genes encoding the secretion function of the Pasteurella haemolytica leukotoxin determinant
57. An SmtB-like repressor from Synechocystis PCC 6803 regulates a zinc exporter
58. Characterization of ylbF, a new gene involved in competence development and sporulation in Bacillus subtilis
59. Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168
60. The genes degQ, pps, and lpa-8 (sfp) are responsible for conversion of Bacillus subtilis 168 to plipastatin production
61. A vector for systematic gene inactivation in Bacillus subtilis
62. Bacillus subtilis operon under the dual control of the general stress transcription factor σ(B) and the sporulation transcription factor Σ(H)
63. Molecular characterization of the operon comprising the spoIV gene of Bacillus megaterium DSM319 and generation of a deletion mutant
64. Metalloregulated expression of the ars operon
65. Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones
66. Difficidin and oxydifficidin: Novel broad spectrum antibacterial antibiotics produced by Bacillus subtilis. I. Production, taxonomy and antibacterial activity