Prostacyclin deficiency and reduced fetoplacental blood flow in pregnancy-induced hypertension and preeclampsia

Gynecologic and Obstetric Investigation

Volumn 50, Issue 2, 2000, Pages 103-107

  Klockenbusch, Walter ^a,b   Goecke, Tamme W ^a   Krüssel, Jan S ^a   Tutschek, Boris A ^a   Crombach, Gerd ^a   Schrör, Karsten ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Doppler ultrasound; Fetoplacental blood flow; Preeclampsia; Pregnancy induced hypertension; Prostacyclin

Indexed keywords

PROSTACYCLIN;

ADULT; ARTICLE; BIRTH WEIGHT; CLINICAL ARTICLE; DOPPLER ECHOGRAPHY; ENDOTHELIUM CELL; FEMALE; FETOPLACENTAL UNIT; FETUS GROWTH; GESTATIONAL AGE; HUMAN; MATERNAL HYPERTENSION; MEDIATOR RELEASE; PLACENTA CIRCULATION; PREECLAMPSIA; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE;

EID: 0033810320     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000010292     Document Type: Article

References (20)

1. National High Blood Pressure Education Program Working Group Report on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 1990;163:1689-1712.
2. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK: Preeclampsia: An endothelial cell disorder. Am J Obstet Gynecol 1989; 161:1200-1204.
3. Walker JJ, Dekker GA: The etiology and pathophysiology of hypertension in pregnancy: in Walker JJ, Gant NF (eds): Hypertension in Pregnancy. London, Chapman & Hall, 1997, pp 39-75.
4. Fitzgerald DJ, Entman SS, Mulloy K, FitzGerald GA: Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension. Circulation 1987;75:956-963.
5. Klockenbusch W, Somville T, Hafner D, Strobach H, Schrör K: Excretion of prostacyclin and thromboxane metabolites before, during, and after pregnancy-induced hypertension. Eur J Obstet Gynecol Reprod Biol 1994;57:47-50.
6. 2 receptor affinity is reduced in pre-eclampsia. Br J Clin Pharmacol 1996;41:616-618.
7. Thompson RS, Trudinger BJ, Cook CM, Giles WB: Umbilical artery velocity waveforms: Normal reference values for A/B ratio and Pourcelot ratio. Br J Obstet Gynaecol 1988;95: 589-591.
8. Roemer VM, Bühler K, Kieback DG: Gestationszeit und Geburtsgewicht (English abstract). Z Gebursthilfe Perinatol 1990;194: 241-253.
9. Klockenbusch W, Braun MS, Schröder H, Heckenberger RE, Strobach H, Schrör K: Prostacyclin rather than nitric oxide lowers human umbilical artery tone in vitro. Eur J Obstet Gynecol Reprod Biol 1992;47:109-151.
10. Glance DG, Elder MG, Myatt L: The actions of prostaglandins and their interactions with angiotensin II in the isolated perfused human placental cotyledon. Br J Obstet Gynaecol 1986; 93:488-494.
11. Soothill PW: Abnormalities of uteroplacental and fetal Doppler studies: in James DK, Steer PJ, Weiner CP, Gonik B (eds): High Risk Pregnancy - Management Options. London, Saunders, 1994, pp 771-781.
12. Myers SA, Sparks JW, Makowski EI, Meschia G, Battaglia FC: Relationship between placental blood flow and placental and fetal size in guinea pig. Am J Physiol 1982;243:H404-H409.
13. Saldeen P, Olofsson P, Marsal K: Lack of association between Doppler velocimetry and synthesis of prostacyclin and thromboxane in umbilical cord vessels from growth retarded fetuses. Acta Obstet Gynecol Scand 1995;74: 103-108.
14. Wetzka B, Schäfer W. Breckwoldt, Zahradnik HP: Eicosanoid production by frozen tissue in vitro is markedly changed. Prostaglandins Leukot Essent Fatty Acids 1994;50:303-304.
15. 2 in the fetoplacental compartment in patients with pregnancy induced hypertension. Prostaglandins 1993;45:509-515.
16. Schrör K, Smith EF: Dictionary of Prostaglandins. Munich, Medikon, 1990, p 41.
17. Mäkilä UM, Jouppila P, Kirikine P, Viinikka L, Ylikorkala O: Relation between umbilical prostacyclin production and blood-flow in the fetus. Lancet 1983;320:728-729.
18. 1+ cellular fibronectin precede the clinical signs of preeclampsia, Am J Obstet Gynecol 1990;162:358-362.
19. Krauss T, Kuhn W, Lakoma C, Augustin HG: Circulating endothelial cell adhesion molecules as diagnostic markers for the early identification of pregnant women at risk for development of preeclampsia. Am J Obstet Gynecol 1997;177:443-449.
20. Konijenberg A, van der Post JAM, Mol BW, Schaap MCL, Lazarov R, Bleker OP, et al: Can flow cytometric detection of platelet activation early in pregnancy predict the occurrence of preeclampsia? A prospective study. Am J Obstet Gynecol 1997;177:434-442.