Induction of p53 in the glutamate-induced cell death program

Amino Acids

Volumn 19, Issue 1, 2000, Pages 253-261

  Uberti, D ^a   Grilli, M ^a   Memo, M ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Amino acids; Cerebellar neurons; Cyclin dependent kinase; Excitotoxicity; Glutamate; Neurodegenerative diseases; Tumour suppressor gene

Indexed keywords

ACETYLSALICYLIC ACID; CYCLIN DEPENDENT KINASE; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CONTROLLED STUDY; DEGENERATIVE DISEASE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; TUMOR SUPPRESSOR GENE;

ANIMAL; APOPTOSIS; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; PROTEIN P53; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION, GENETIC;

EID: 0033806857     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007260070056     Document Type: Article

References (42)

1. High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro
2. Stimulation of HIV type 1 gene expression and induction of NF-kappa B (p50/p65)-binding activity in tumor necrosis factor alpha-treated human fetal glial cells
3. Kainic acid activation of the DNA mismatch repair protein MSH2 in rat brain
4. Induction of two DNA mismatch reair proteins, MSH2 and MSH6, in differentiated human neuroblastoma SH-SY5Y cells exposed to doxorubicin
5. DNA repair and Alzheimer's disease
6. Glutamate neurotoxicity and diseases of the nervous system
7. p53 Expression in brain after middle cerebral artery occlusion in the rat
8. Drug-induced neuroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-κB in rats
9. Activation of nuclear factor-kappa B in brains from children with HIV-1 encephalitis
10. Changes in brain gene expression shared by scrapie and Alzheimer's disease
11. p53 Plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells
12. WAF1, a potent mediator of p53 tumor suppression
13. Possible role of NF-κB and p53 in glutamate-induced pro-apoptotic neuronal pathway
14. Interleukin-1β and glutamate activate the NF-κB/Rel binding site from the regulatory region of the amyloid precursor protein gene in primary neuronal cultures
15. Neuroprotection by salicylate through blockade of NF-κB activation
16. Bcl-2 down-regulates the activity of transcription factor NF-kappa B induced upon apoptosis
17. Methamphetamine-induced serotonin neurotoxicity is attenuated in p53-knockout mice
18. Nuclear translocation of NF-κB is increased in dopaminergic neurons of patients with Parkinson's disease
19. Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis
20. Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease
21. Cytokine-induced programmed cell death of cultured sympathetic neurons
22. p53-Immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats
23. Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B
24. Excitatory amino acids as a final common pathway for neurologic disorders
25. Damage, repair, and mutagenesis in nuclear genes after mouse forebrain ischemia-reperfusion
26. DNA repair mechanism in neurological diseases: Facts and hypoteses
27. Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death
28. Neuronal necrosis and apoptosis: Two distinct events induced by exposure to glutamate or oxidative stress
29. Mismatch repair and cancer
30. Evidence of apoptotic cell death in Huntington disease and excitotoxic animal model
31. Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum
32. Parkinson's disease and Alzheimer's disease: Hypersensitivity to X rays in cultured cell lines
33. p53 Induction is associated with neuronal damage in the central nervous system
34. Specific in vitro binding of p53 to the promoter region of the human mismatch repair hMSH2
35. Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: Protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crm-A
36. Transcription factor DNA binding activity in PC12 cells undergoing apoptosis after glucose deprivation
37. Induction of tumour suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurons triggered by excitatory aminoacids
38. Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons
39. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide
40. Increased cortical nuclear factor-kappa B (NF-kappa B) DNA binding activity after traumatic brain injury in rats
41. The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB Kinase-β
42. Evidence for p53-mediated modulation of neuronal viability