Differences in degree of trapping between AR-R15896 and other uncompetitive NMDA receptor antagonists

Amino Acids

Volumn 19, Issue 1, 2000, Pages 173-175

  Lanthorn, T H ^a   Mealing, G A R ^b   Morley, P ^b  

^a ASTRAZENECA   (United Kingdom)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Amino acids; NMDA; Partial trapping; Use dependence

Indexed keywords

ALPHA PHENYL 2 PYRIDINEETHANAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

BINDING AFFINITY; DRUG EFFICACY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SCREENING; EPILEPSY; HUMAN; NERVE DEGENERATION; PRIORITY JOURNAL; SHORT SURVEY; SIDE EFFECT;

EXCITATORY AMINO ACID ANTAGONISTS; PYRIDINES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0033805424     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007260070046     Document Type: Short Survey

References (2)

1. Antagonism of N-methyl-D-aspartate-evoked currents in rat cortical cultures by ARL 15896AR
2. Differences in degree of trapping of low-affinity uncompetitive N-methyl-D-aspartic acid receptor antagonists with similar kinetics of block