Fetal cells in the mother: From genetic diagnosis to diseases associated with fetal cell microchimerism

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 92, Issue 1, 2000, Pages 103-108

  Bianchi, Diana W ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b Division of Newborn Medicine   (United States)

Author keywords

Fetal; Genetic diagnosis; Maternal disease; Microchimerism

Indexed keywords

DIAGNOSTIC VALUE; FETUS CELL; FETUS DISEASE; GENETIC DISORDER; HUMAN; MICROCHIMERISM; PLACENTAL TRANSFER; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; REVIEW;

EID: 0033804933     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-2115(00)00432-2     Document Type: Article

References (29)

1. Bianchi D.W. Fetal cells in the maternal circulation: feasibility for prenatal diagnosis. Br. J. Haematol. 105:1999;574-583.
2. Aractingi S., Berkane N., Berthean P., Le Goue′ C., Dausset J., Uzan S., Carosella E.D. Fetal DNA in skin of polymorphic eruptions of pregnancy. Lancet. 352:1998;1898-1901.
3. Holzgreve W., Ghezzi E., DiNaro E., Ganshirt D., Maymon E., Hahn S. Fetomaternal cell traffic is disturbed in pre-eclampsia. Obstet. Gynecol. 91:1998;669-672.
4. Nelson J.L., Furst D.E., Maloney S., Gooley T., Evans P.C., Smith A., Bean M.A., Ober C., Bianchi D.W. Microchimerism and HLA - compatible relationships of pregnancy in scleroderma. Lancet. 351:1998;559-562.
5. Artlett C.M., Smith J.B., Jimenez S.A. Identification of fetal DNA and cells in skin lesions from women with systemic sclerosis. N. Engl. J. Med. 338:1998;1186-1191.
6. Haddow J.E., Palomaki G.E., Knight G.J., Williams J., Miller W.A., Johnson A. Screening of maternal serum for fetal Down's syndrome in the first trimester. N. Engl. J. Med. 338:1998;955-961.
7. Wald N.J., Walt H.C., Hackshaw A.K. Integrated screening for Down's syndrome on the basis of tests performed during the first and second trimesters. N. Engl. J. Med. 341:1999;461-467.
8. American College of Obstetrics and Gynocology Committee on Genetics. Opinion Number 223, October 1999.
9. Snijders R.J., Noble P., Sebire N., Souka A., Nicolaides K.H. UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10-14 weeks of gestation. Fetal Medicine Foundation First Trimester Screening Group. Lancet. 352:1998;343-346.
10. Farina A., Bianchi D.W. Fetal cells in maternal blood as a second non-invasive step for fetal Down's syndrome screening. Prenat. Diagn. 18:1998;983-984.
11. Ganshirt D., Sneets F.W., Dohr A., Walde C., Steen I., Lapucci C., Falcirelli C., Sant R., Velasco M., Garritsen H.S., Holzgreve W. Enrichment of fetal nucleated red blood cells from the maternal circulation for prenatal diagnosis: experiences with triple density gradient and MACS based on more than 600 cases. Fetal Diagn. Ther. 13:1998;276-286.
12. Lewis D.E., Schober W., Murrel S., Nguyen D., Scott J., Boinoff J., Simpson J.L., Bischoff Z., Elias S. Rare event selection of fetal nucleated erythrocytes in maternal blood by flow cytometry. Cytometry. 23:1996;218-227.
13. Oosterwijk J.C., Mesker W.E., Ouwerkerk M.C., Knepfle C.F., van der Burg M.J., Wiesmeijer C.C., Beverstock G.C., Bernini L.F., van Ommen G.J., Kanhai H.H., Tanke H.J. Development of a preparation and staining method for fetal erythroblasts in maternal blood: simultaneous immunocytochemical staining and FISH analysis. Cytometry. 32:1998;170-177.
14. de la Cruz F., Shifrin H., Elias S., Bianchi D.W., Jackson L., Evans M.I., Holzgreve W., Klinger K. Low false-positive rate of aneuploids detection using fetal cells isolated from maternal blood. Fetal. Diagn. Ther. 13:1998;380.
15. Bianchi D.W., Simpson J.L., Jackson L.G., Evans M.I., Elias S., Holzgreve W., Sullivan L.M., de la Cruz F. Fetal cells in maternal blood: NIFTY clinical trial interim analysis. NICHD fetal cell study (NIFTY) group. Prenat. Diagn. 19:1999;994-995.
16. Bianchi D.W., Williams J.M., Sullivan L.M., Hanson F.W., Klinger K.W., Shuber A.P. PCR quantitation of fetal cells in maternal blood in normal and aneuploid pregnancies. Am. J. Hum. Genet. 61:1997;822-829.
17. Lo Y.M.D., Tein M.S.C., Lan T.K., Haines C.J., Leung T.N., Poon P.M.K., Wainscoat J.S., Johnson P.J., Chang A.M.Z., Hjelm N.M. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for non-invasive prenatal diagnosis. Am. J. Hum. Genet. 62:1998;768-775.
18. Lo Y.M.D., Lau T.K., Zhang J., Leung T.N., Chang A.M.Z., Hjelm N.M., Elmes R.S., Bianchi D.W. Increased fetal DNA concentrations in the plasma of pregnant women carrying fetuses with trisomy 21. Clin. Chem. 45:1999;1747-1751.
19. Lo Y.M., Hjelm N.M., Fidler C., Sargent I.L., Murphy M.F., Chamberlain P.F., Poon P.M., Redman C.W., Wainscoat J.S. Prenatal diagnosis of RhD status by molecular analysis of maternal plasma. N. Engl. J. Med. 339:1998;1734-1738.
20. Lo Y.M., Leung T.N., Tein M.S., Sargent I.L., Zhang J., Lau T.K., Haines C.J., Redman C.W. Quantitative abnormalities of fetal DNA in maternal serum in pre-eclampsia. Clin. Chem. 45:1999;184-188.
21. Leung T.N., Zhang J., Lau T.K., Hjelm N.M., Lo Y.M. Maternal plasma fetal DNA as a marker for preterm labour. Lancet. 352:1998;1904-1905.
22. Lo Y.M., Zhang J., Leung T.N., Lau T.K., Chang A.M., Hjelm N.M. Rapid clearance of fetal DNA from maternal plasma. Am. J. Hum. Genet. 64:1999;218-224.
23. Bianchi D.W., Zickwolf G.K., Weil G.J., Sylvester S., DeMaria M.A. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. Proc. Natl. Acad. Sci. U. S. A. 93:1996;705-708.
24. Bianchi D.W., Farina A., Genova M., Weber W., Williams J.M., Klinger K.W. PCR quantitation of fetal cells in maternal blood after voluntary interruption of pregnancy: implications for diseases associated with microchimerism. Am. J. Human. Genet. 63:1998;A6.
25. Nelson J.L. Viewpoint: Maternal-fetal immunology and autoimmune disease: is some autoimmune disease auto-alloimmune or allo-autoimmune? Arthr. Rheum. 39:1996;191-194.
26. Tanaka A., Lindor K., Gish R., Batts K., Shiratori Y., Omata M., Nelson J.L., Ansari A., Coppel R., Newsome M., Gershwin M.E. Fetal microchimerism alone does not contribute to the induction of primary biliary cirrhosis. Hepatology. 30:1999;833-838.
27. Johnson K.L., Zhen D.K., Srivatsa B., McAlindon T., Nelson J.L., Bianchi D.W. Fetal cell microchimerism: FISH deletion of male cells in females with autoimmune disease. Am. J. Hum. Genet. 65:1999;A23.
28. Aractingi S, Uzan S, Dausset J, Carosella ED. Microchimerism in human diseases. Immun Today 2000;21:116-8.
29. Christner PJ, Artlett CA, Conway RF, Jimenez SA. Increased numbers of microchimeric cells of fetal origin are associated with dermal fibrosis in mice following injection of vinyl chloride. Arth Rheum; in press.