Attention-deficit hyperactivity disorder and the gene for the dopamine D5 receptor

Molecular Psychiatry

Volumn 5, Issue 5, 2000, Pages 548-551

  Barr, C L ^a,b   Wigg, K G ^a   Feng, Y ^a   Zai, G ^a   Malone, M ^b   Roberts, W ^b   Schachar, R ^b   Tannock, R ^b   Kennedy, J L ^c  

^a TORONTO WESTERN HOSPITAL   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Attention deficit hyperactivity disorder; Dopamine receptor D5; Genetics; Transmission disequilibrium test

Indexed keywords

DOPAMINE 5 RECEPTOR;

ARTICLE; ATTENTION DEFICIT DISORDER; CAUCASIAN; COSMID; DNA POLYMORPHISM; ETHNOLOGY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

EID: 0033804017     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000777     Document Type: Article

References (23)

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2. Cloning of the human dopamine D5 receptor gene and identification of a highly polymorphic microsatellite for the DRD5 locus that shows tight linkage to the chromosome 4p reference marker RAF1P1
3. Localization of the D5 dopamine receptor gene to human chromosome 4p15.1-p15.3, centromeric to the Huntington's disease locus
4. Multiple human D5 dopamine receptor genes: A functional receptor and two pseudogenes
5. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1
6. Linkage study of the dopamine D5 receptor gene and Gilles de la Tourette syndrome
7. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
8. The D5 dopamine receptor gene in schizophrenia: Identification of a nonsense change and multiple missense changes but lack of association with disease
9. Scanning of the dopamine D1 and D5 receptor genes by REF in neuropsychiatric patients reveals a novel missense change at a highly conserved amino acid
10. Functional analysis of the human D5 dopamine receptor missense and nonsense variants: Differences in dopamine binding affinities
11. Linkage study of catechol-O-methyltransferase and attention-deficit hyperactivity disorder
12. Linkage study of two polymorphisms at the dopamine D3 receptor gene and attention-deficit hyperactivity disorder
13. Identification of DNA variants in the SNAP-25 gene and linkage study of these polymorphisms and attention-deficit hyperactivity disorder
14. Further evidence from haplotype analysis for linkage of the dopamine D4 receptor gene and attention-deficit hyperactivity disorder
15. Deficient inhibitory control in attention deficit hyperactivity disorder
16. Evaluation of the revised Ontario Child Health Study scales
17. A simple salting out procedure for extracting DNA from human nucleated cells