The effects of allopurinol in hepatic ischemia and reperfusion: Experimental study in rats

European Surgical Research

Volumn 32, Issue 4, 2000, Pages 215-222

  Rhoden, E ^a   Pereira Lima, L ^a,d   Lucas, M ^b   Mauri, M ^b   Rhoden, Cláudia ^b   Pereira Lima, J C ^b   Zettler, C ^b   Petteffi, L ^c   Belló Klein, Adriane ^c  

^a HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^b Federal School of Medical Sciences of Porto Alegre   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d NONE   (Brazil)

Author keywords

Allopurinol; Ischemia, hepatic; Lipid peroxidation; Oxygen free radicals

Indexed keywords

ALANINE AMINOTRANSFERASE; ALLOPURINOL; ASPARTATE AMINOTRANSFERASE; OXYGEN RADICAL; TERT BUTYL HYDROPEROXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; XANTHINE OXIDASE; XANTHINE OXIDASE INHIBITOR;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENZYME INHIBITION; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER FUNCTION TEST; LIVER INJURY; LIVER ISCHEMIA; LIVER NECROSIS; LIVER PROTECTION; LIVER SURGERY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TREATMENT OUTCOME;

EID: 0033802891     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000008767     Document Type: Article

References (36)

1. McCord JM: Oxygen-derived free radicals in postischemia tissue injury. N Engl J Med 1985; 312:159-163.
2. Hasselgren P: Prevention and treatment of ischemia of the liver: Surg Gynecol Obstet 1987;164:187-196.
3. Jones DP: Oxidative Stress. San Diego, Academic Press, 1985, pp 151-189.
4. Bulkley GB: The role of oxygen free radicals in human disease process. Surgery 1983;94:407-411.
5. Marubayashi S, Dohi K, Yamada K, Kawasaki T: Role of conversion of xanthine dehydrogenase to oxidase in ischemia rat liver cell injury. Surgery 1991;110:537-543.
6. Marubayashi S, Dohi K, Ochi K, Kawasaki T: Role of free radicals in ischemia rat liver cell injury: Prevention of damage by alpha-tocopherol administration. Surgery 1985;99:184-191.
7. Takemoto Y: Changes in calcium content of liver during hepatic ischemia-reperfusion in dogs. J Hepatol 1994;21:743-747.
8. Cohen PJ: Allopurinol administered prior to hepatic ischemia in the rat prevents chemiluminescence following restoration of circulation. Can J Anaesth 1992;39:1090-1093.
9. Karwinski W, Bolann B, Ulvik R, Farstad M, Soreide O: Normothermic liver ischemia in rats: Xanthine oxidase is not the main source of free radicals. Res Exp Med (Berl) 1993;193: 275-283.
10. Buege JA, Aust SD: Microsomal lipid peroxidation. Methods Enzymol 1978;52:302-309.
11. Gonzalez-Flecha B, Llesuy S, Boveris A: Hydroperoxide-initiated chemiluminescence: An assay for oxidative stress in biopsies of heart, liver and muscle. Free Radic Biol Med 1991; 10:93-100.
12. Llesuy SF, Milei J, Molina H, Boveris A, Milei S: Comparison of lipid peroxidation and myocardial damage induced by adriamycin and 4′-epiadriamycin in mice. Tumori 1985;71:241-249.
13. Lowry OH, Rosebrough MJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
14. Jaeschke H, Bautista AP, Spolarics Z, Spitzer JJ: Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia. Free Radic Res Commun 1991;15:277-284.
15. Mathews WR, Guido DM, Fisher MA, Jaeschke H: Lipid peroxidation as molecular mechanism of liver cell injury during reperfusion after ischemia. Free Radic Biol Med 1994; 16:763-770.
16. Hamer I, Wattiaux R, Wattiaux-De Coninck S: Deleterious effect of xanthine oxidase on rat liver endothelial cells after ischemia-reperfusion. Biochim Biophys Acta 1995;1269:145-152.
17. Müller MJ, Vollmar B, Friedl HP, Menger MD: Xanthine oxidase and superoxide radicals in portal triad crossclamping-induced microvascular reperfusion injury of the liver. Free Radic Biol Med 1996;21:189-197.
18. Hirasawa H, Chaudry IH, Baue AE: Improved hepatic function and survival with adenosine triphosphate-magnesium chloride after hepatic ischemia. Surgery 1978;83:655-662.
19. Fortner JG, Shiu MH, Kinne DW: Major hepatic resection using vascular isolation and hypothermic perfusion. Ann Surg 1974;180:644-652.
20. Rhoden EL, Mauri M, Petteffi L, Kalil AN, Pereira-Lima L, Rhoden CR: Lipid peroxidation of hepatocyte membranes caused by free radicals in liver submitted to ischemia/reperfusion: Experimental model in rats. Rev Bras Cir 1996;86:3-5.
21. Nauta RJ, Tsimoyiannis E, Uribe M: Oxygen-derived free radicals in hepatic ischemia and reperfusion injury in the rat. Surg Gynecol Obstet 1990;171:120-125.
22. Foschi D, Castoli L, Lesma A: Effects of ischaemia and reperfusion on liver regeneration in rats. Eur J Surg 1993;159:393-398.
23. Lucas ML, Sabedotti M, Dacanal FM, Rhoden CR, Rhoden EL: Protector effect of α-tocopherol in damage caused by oxygen free radicals during renal ischemia and reperfusion. Acta Cir Bras 1998; 13(1): 129.
24. Nordström G, Seeman T, Hasselgren PO: Beneficial effect of allopurinol in liver ischemia. Surgery 1985;97:679-684.
25. Durmus O, Aricioglu A, Guven T, Oguz M, Yel M, Turkozkan N: The effect of allopurinol on the liver ultrastructure, reduced glutathione and lipid peroxide levels during liver ischemia in guinea pigs. Gen Pharmacol 1994;25:781-786.
26. Paller MS, Hoidal JR, Ferris TF: Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest 1984;74:1156-1164.
27. Kobayashi H, Nonami T, Kurokawa T, Takeuchi Y, Harad A, Nakao A, Takagi H: Role of endogenous nitric oxide in ischemia-reperfusion inury in rat liver. J Surg Res 1995;59:772-779.
28. Takayama F, Egashira T, Yamanaka Y: Effect of diclofenac, a non-steroidal anti-inflammatory drug, on lipid peroxidation caused by ischemia-reperfusion in ral liver. Jpn J Pharmacol 1994;62:71-78.
29. Lucas ML, Rhoden CR: Therapeutic potential of inhibitors of the enzyme nitric oxide synthase. Rev Bras Clin Ter 1999;25:28-36.
30. Menger MD: Microcirculatory disturbance secondary to ischemia-reperfusion. Transplant Proc 1995;27:2863-2865.
31. Lucas ML, Rhoden EL, Rhoden CR, Belló-Klein A, Telöken C: Interaction between nitric oxide and oxygen active species during renal ischemia-reperfusion in rats. Rev Col Bras Cir 1999;26(suppl.):83.
32. Imamura H, Sutto F, Brault A, Huet PM: Role of Kupffer cells in cold ischemia-reperfusion injury of rat liver. Gastroenterology 1995;109: 189-197.
33. Metzger J, Lauterburg BH: Effect of allopurinol on oxidant stress and hepatic function following ischemia and reperfusion in the rat. Liver 1988;8:344-349.
34. Chavez-Cataya R, Desola GP, Ramirez-Romero P, Calne SRY, Jamieson NV: Ischemia and reperfusion injury of the rat liver: The role of nimodipine. J Surg Res 1996;60:199-206.
35. Karwinski W, Soreide D: Allopurinol improves scavenging of the liver after ischemia-reperfusion injury. Liver 1997;17:139-143.
36. Shito M, Wakabayashi G, Masakaza V, Shimazu, M, Shirasugi N, Endo M, Mukai M, Kitajima M: Interleukin-1-receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia ischemia-reperfusion in the rat. Transplantation 1997; 63:143-148.