Ischemia and reperfusion injury of the rat liver: The role of nimodipine

Journal of Surgical Research

Volumn 60, Issue 1, 1996, Pages 199-206

  Chav́ez Cartaya, Rafael E ^a   Desola, Gilda Pino ^a   Ramirez Romero, Pablo ^a   Calne, Roy Y ^a   Jamieson, Neville V ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CALCIUM CHANNEL BLOCKING AGENT; GALACTOSE; NIMODIPINE; OXYHEMOGLOBIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER BLOOD FLOW; LIVER ISCHEMIA; LIVER TRANSPLANTATION; MALE; NONHUMAN; ORGAN PRESERVATION; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

EID: 0342313496     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1996.0032     Document Type: Article

References (50)

1. Clavien, P., Harvey, R., and Strasberg, S. Preservation and reperfusion injuries in liver allografts. Transplantation 53(5): 957, 1992.
2. Kerrigan, C., and Stotland, M. Ischaemia reperfusion injury: A review. Microsurgery 14: 166, 1993.
3. Farber, J., Chien, K., and Mittnacht, S. The pathogenesis of irreversible cell injury in ischemia. Am. J. Pathol. 102(2): 271, 1981.
4. Farber, J., and Young, E. Accelerated phospholipid degradation in anoxic rat hepatocytes. Arch. Biochem. Biophys. 211(1): 312, 1981.
5. Kayawake, S., Narbaitz, R., and Kako, K. J. Effects of chloroquine and nifedipine on the phospholipid content and enzyme activity in the subcellular fraction of ischemic rat liver. Basic Res. Cardiol. 77: 140, 1982.
6. Chávez-Cartaya, R., Ramirez, P., and Jamieson, N. V. Liver ischaemia and reperfusion in the rat. The role of chloroquine, a phospholipase inhibitor, in post-ischaemic liver blood flow. Br. J. Surg. 80(Suppl.): S50, 1993.
7. Stein, H., Oosthuyzen, M., Hinder, R., and Lamprechts, H. Effect of verapamil on hepatic ischemia/reperfusion injury. Am. J. Surg. 165: 96, 1993.
8. Caldwell-Kenkel, J., Thurmann, R., and Lemasters, J. Selective loss of nonparenchimal cell viability after cold ischemic storage of rat livers. Transplantation 45(4): 834, 1988.
9. Caldwell-Kenkel, J., Currin, R., Tanaka, Y., Thurman, R., and Lemasters, J. Reperfusion injury to endothelial cells following cold ischemic storage of rat livers. Hepatology 10(3): 292, 1989.
10. Walsh, T., Rao, P., Makowka, L., and Starzl, T. Lipid peroxidation is a nonparenchimal cell event with reperfusion after prolonged liver ischemia. J. Surg. Res. 49: 18, 1990.
11. McKeown, C., Edwards, V., Philips, M., Harvey, P., Petrunka, C., and Strasberg, S. Sinusoidal lining cell damage: The critical injury in cold preservation of liver allografts in the rat. Transplantation 46(2): 178, 1988.
12. Takei, Y., Marzi, I., Kaufmann, F., Currin, R., Lemasters, J., and Thurmann, R. Increase in survival time of liver transplants by protease inhibitors and a calcium channel blocker nisoldipine. Transplantation 50(1): 14, 1990.
13. Crawford, M., Grover, F., Kolb, W., McMahan, A., O'Rourke, R., McManus, L., and Pinckard, N. Complement and neutrophil activation in the pathogenesis of ischemic myocardial injury. Circulation 78: 1449, 1988.
14. Maroko, P., Carpenter, C., Chiarielllo, M., Fishbein, M., Radvani, P., Knostman, J., and Hale, S. Reduction by cobra venom factor of myocardial necrosis after coronary occlussion. J. Clin. Invest. 61: 661, 1978.
15. Jaeschke, H., Farhood, A., and Smith, C. W. Neutrophils contribute to ischemia-reperfusion injury in rat liver in vivo. FASEB J. 4(15): 3355, 1990.
16. Chávez-Cartaya, R., Pino DeSola, G., Horsley, J., Jamieson, N. V., and White, D. J. G. Protective effect of soluble complement receptor 1 (sCR1) on reperfusion injury in the rat liver. Intensive Care Med. 20(Suppl. 1): S95, 1994, [Abstract]
17. Chávez-Cartaya, R., Pino DeSola, G., Wright, L., Jamieson, N., and White, D. J. G. The regulation of the complement cascade by soluble complement receptor type 1 (sCR1). Protective effect in experimental liver ischaemia and reperfusion. Transplantation 59(7): 1047, 1995.
18. Ryan, U. The endothelial surface and responses to injury. Fed. Proc. 45(2): 101, 1986.
19. Ar'Rajab, A., Ahrén, B., and Bengmark, S. Improved liver preservation for transplantation due to calcium channel blockade. Transplantation 51(5): 965, 1991.
20. Tokunaga, Y., Collins, G., Esquivel, C., and Wicomb, W. Calcium antagonists in sodium lactobionate sucrose solution for rat liver preservation. Transplantation 53(4): 723, 1992.
21. Chávez-Cartaya, R., Pifano, E., Vegas, A., Meijomil, P., and Sorio, L. Isquemia y reperfusión hepática en ratas. Efecto de la nimodipina y la clorpromazina. Rev. Venez. Cir. 44(2): 61, 1991.
22. Shinohara, M., Kayashima, K., and Konomi, K. Protective effect of verapamil on ischaemia-induced hepatic damage in the rat. Eur. Surg. Res. 22: 256, 1990.
23. Nauta, R., Tsimoyiannis, E., Uribe, M., Walsh, D., Miller, D., and Butterfield, A. The role of calcium ions and calcium channel entry blockers in experimental ischemia-reperfusion-induced liver injury. Ann. Surg. 213(2): 137, 1991.
24. Baker, H. de C. Isehaemic necrosis in the rat liver. J. Pathol. Bacteriol. 71: 135, 1956.
25. Nilsson, G., Tenland, T., and Oberg, P. A. Evaluation of a laser Doppler flowmeter for measurement of tissue blood flow. IEEE Trans. Biomed. Eng. BME-27(10): 597, 1980.
26. Oberg, P. A. Laser-Doppler flowmetry. Crit. Rev. Biomed. Eng. 18(2): 125, 1990.
27. Almond, N., and Wheatley, A. M. Measurement of hepatic perfusion in rats by laser Doppler flowmetry. Am. J. Physiol. 262 (Gastrointest. Liver Physiol. 25): G203, 1992.
28. Chávez-Cartaya, R., Ramirez, P., Calne, R. Y., and Jamieson, N. V. Laser Doppler flowmetry in the study of in vivo liver ischaemia and reperfusion in the rat. J. Surg. Res. 56: 473, 1994.
29. Pologe, J. Pulse oximetry: Technical aspects of machine design. Int. Anesthesia Clin. 25(3): 137, 1987.
30. Chávez-Cartaya, R., Ramirez, P., and Jamieson, N. V. Heamoglobin saturation in the rat liver after ischaemia and reperfusion: Study using a laser photometry technique, and correlation with changes in liver tissue blood flow. Eur. Surg. Res. 27: 82, 1995.
31. Sevick, E., Chance, B., Leigh, J., Nioka, S., and Maris, M. Quantitation of time- and frequency-resolved optical spectra for the determination of tissue oxygenation. Anal. Biochem. 195: 330, 1991.
32. Chávez-Cartaya, R., Metcalfe, S., Ramirez, P., Calne, R. Y., and Jamieson, N. V. Rat liver blood flow after ischaemia and reperfusion: Effect of the platelet activating factor antagonist WEB-2170 and of removing circulating leukocytes. Transplantation 57(10): 1440, 1994.
33. Diepenbrock, F., Heckler, R., Schickling, H., Engelhard, T., Bock, D., and Sander, J. Colorimetric determination of galactose and galactose 1-phosphate from dried blood. Clin. Biochem. 25: 37, 1992.
34. Karp, G. Cytoskeleton. In G. Karp, (Ed.), Cell Biology. New York: McGraw-Hill, 1984. 2nd ed.
35. Thurmann, R., King, J., and Lemasters, J. Nitrendipine protects the liver against hypoxia-induced damage at submicromolar concentrations in the perfused rat liver. J. Cardiovasc. Pharmacol. 9(Suppl. 4): S71, 1987.
36. Lemons, V., Chehrazi, B., Kauten, R., Hein, L., and Wagner, F. The effect of nimodipine on high energy phosphates and intracellular pH during cerebral ischaemia. J. Neurotrauma 10(1): 73, 1993.
37. Gunn, A., and Gluckmann, P. Flunarizine, a calcium channel antagonist is not neuroprotective when given after hypoxiaischaemia in the infant rat. Dev. Pharmacol. Ther. 17: 205, 1991.
38. Liang, D., and Thurmann, R. Protective effect of the calcium antagonists diltiazem and TA3090 against hepatic injury due to hypoxia. Biochem. Pharmacol. 44(11): 2207, 1992.
39. Marzi, I., Walcher, F., and Buhren, V. Macrophage activation and leukocyte adhesion after liver transplantation. Am. J. Physiol. 265(1): G172, 1993.
40. 2+ antagonists do not protect isolated perfused rat hepatocytes from anoxic injury. Biochim. Biophys. Acta 1177: 1, 1993.
41. Arvidsson, D., Svennson, H., and Haglund, U. Laser-Doppler flowmetry for estimation of liver blood flow. Am. J. Physiol. 254 (Gastrointest. Liver Physiol. 17): G471, 1988.
42. Sjovall, S., and Svensson, H. Effect of hepatic artery or portal vein occlusion on liver tumour blood flow. Eur. Surg. Res. 23: 179, 1991.
43. Vongsavan, N., and Matthews, B. Some aspects of the use of laser doppler flow meters for recording tissue blood flow. Exp. Physiol. 78: 1, 1993.
44. Wheatley, A., Almond, N., Stuart, E., and Zhao, D. Interpretation of the laser Doppler flow signal from the liver of the rat. Microvasc. Res. 45: 290, 1993.
45. Suzuki, S., Toledo-Pereyra, L., Rodriguez, F., and Cejalvo, D. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 55: 1265, 1993.
46. Lindskow, J. The quantitative liver function as measured by the galactose elimination capacity. Acta Med. Scand. 212: 295, 1982.
47. Winkler, K., Henriksen, J., and Tygstrup, N. Hepatic, renal and total body galactose elimination in the pig. Am. J. Physiol. 265(28): G9, 1993.
48. Gross, J., Reichen, J., Zeltner, T., and Zimmermann, A. The evolution of changes in quantitative liver function tests in a rat model of biliary cirrhosis: Correlation with morphometric measurement of hepatocyte mass. Hepatology 7(3): 457, 1987.
49. Reichen, J., Egger, B., Ohara, N., Zeltner, T., Zysset, T., and Zimmermann, A. Determinants of hepatic function in liver cirrhosis in the rat. J. Clin. Invest. 82: 2069, 1988.
50. McKelvey, T. G., Hollwarth, M., Granger, D., Engerson, T., Landler, U., and Jones, H. Mechanism of conversion of xanthine dehydrogenase to xanthine oxidase in ischaemic rat liver and kidney. Am. J. Physiol. 254: G753, 1988.